A three-dimensional vessel-on-chip model to study Puumala orthohantavirus pathogenesis.

Autor: Noack D; Department of Viroscience, Erasmus University Medical Center, s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. b.rockx@erasmusmc.nl., van Haperen A; Department of Viroscience, Erasmus University Medical Center, s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. b.rockx@erasmusmc.nl., van den Hout MCGN; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Center for Biomics, Erasmus University Medical Center, Rotterdam, the Netherlands., Marshall EM; Department of Viroscience, Erasmus University Medical Center, s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. b.rockx@erasmusmc.nl., Koutstaal RW; Department of Viroscience, Erasmus University Medical Center, s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. b.rockx@erasmusmc.nl., van Duinen V; Department of Internal Medicine, Division of Nephrology and the Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands., Bauer L; Department of Viroscience, Erasmus University Medical Center, s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. b.rockx@erasmusmc.nl., van Zonneveld AJ; Department of Internal Medicine, Division of Nephrology and the Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands., van IJcken WFJ; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Center for Biomics, Erasmus University Medical Center, Rotterdam, the Netherlands., Koopmans MPG; Department of Viroscience, Erasmus University Medical Center, s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. b.rockx@erasmusmc.nl., Rockx B; Department of Viroscience, Erasmus University Medical Center, s-Gravendijkwal 230, 3015 CE, Rotterdam, the Netherlands. b.rockx@erasmusmc.nl.

Publikováno v: Lab on a chip [Lab Chip] 2024 Sep 18. Date of Electronic Publication: 2024 Sep 18.

Unraveling the impact of AXIN1 mutations on HCC development: Insights from CRISPR/Cas9 repaired AXIN1-mutant liver cancer cell lines.

Autor: Zhang R; Department of Gastroenterology and Hepatology, Erasmus Medical Center Cancer Institute, University Medical Center, Rotterdam, The Netherlands.; Yunnan Key Laboratory of Chiral Functional Substance Research and Application, School of Chemistry & Environment, Yunnan Minzu University, Kunming, China., Li S; Department of Gastroenterology and Hepatology, Erasmus Medical Center Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Schippers K; Department of Gastroenterology and Hepatology, Erasmus Medical Center Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Eimers B; Department of Gastroenterology and Hepatology, Erasmus Medical Center Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Niu J; Department of Gastroenterology and Hepatology, Erasmus Medical Center Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Hornung BVH; Erasmus Center for Biomics, Erasmus University Medical Center, Rotterdam, The Netherlands., van den Hout MCGN; Erasmus Center for Biomics, Erasmus University Medical Center, Rotterdam, The Netherlands., van Ijcken WFJ; Erasmus Center for Biomics, Erasmus University Medical Center, Rotterdam, The Netherlands., Peppelenbosch MP; Department of Gastroenterology and Hepatology, Erasmus Medical Center Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Smits R; Department of Gastroenterology and Hepatology, Erasmus Medical Center Cancer Institute, University Medical Center, Rotterdam, The Netherlands.

Publikováno v: PloS one [PLoS One] 2024 Jun 07; Vol. 19 (6), pp. e0304607. Date of Electronic Publication: 2024 Jun 07 (Print Publication: 2024).

Comparison of Single Cell Transcriptome Sequencing Methods: Of Mice and Men.

Autor: Hornung BVH; Department of Cell Biology, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands.; Genomics Core Facility, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands., Azmani Z; Department of Cell Biology, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands.; Genomics Core Facility, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands., den Dekker AT; Department of Cell Biology, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands.; Genomics Core Facility, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands., Oole E; Department of Cell Biology, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands.; Genomics Core Facility, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands., Ozgur Z; Department of Cell Biology, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands.; Genomics Core Facility, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands., Brouwer RWW; Department of Cell Biology, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands.; Genomics Core Facility, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands., van den Hout MCGN; Department of Cell Biology, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands.; Genomics Core Facility, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands., van IJcken WFJ; Department of Cell Biology, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands.; Genomics Core Facility, Erasmus University Medical Center Rotterdam, Wytemaweg 80, 3015CN Rotterdam, The Netherlands.

Publikováno v: Genes [Genes (Basel)] 2023 Dec 16; Vol. 14 (12). Date of Electronic Publication: 2023 Dec 16.

Molecular analysis of the erythroid phenotype of a patient with BCL11A haploinsufficiency.

Autor: Wessels MW; Department of Clinical Genetics., Cnossen MH; Department of Pediatric Hematology.; Academic Center for Hemoglobinopathies and Rare Anemias., van Dijk TB; Academic Center for Hemoglobinopathies and Rare Anemias.; Department of Cell Biology, and., Gillemans N; Academic Center for Hemoglobinopathies and Rare Anemias.; Department of Cell Biology, and., Schmidt KLJ; Academic Center for Hemoglobinopathies and Rare Anemias.; Department of Cell Biology, and., van Lom K; Academic Center for Hemoglobinopathies and Rare Anemias.; Department of Hematology, Erasmus MC, Rotterdam, The Netherlands., Vinjamur DS; Division of Hematology/Oncology, Department of Pediatric Oncology, Boston Children's Hospital, Boston, MA.; Dana-Farber Cancer Institute, Boston, MA.; Harvard Stem Cell Institute, Boston, MA.; Broad Institute, Boston, MA.; Department of Pediatrics, Harvard Medical School, Boston, MA., Coyne S; Division of Hematology/Oncology, Department of Pediatric Oncology, Boston Children's Hospital, Boston, MA.; Dana-Farber Cancer Institute, Boston, MA.; Harvard Stem Cell Institute, Boston, MA.; Broad Institute, Boston, MA.; Department of Pediatrics, Harvard Medical School, Boston, MA., Kurita R; Department of Research and Development, Central Blood Institute, Blood Service Headquarters, Japanese Red Cross Society, Tokyo, Japan., Nakamura Y; Cell Engineering Division, RIKEN, BioResource Center, Tsukuba, Japan., de Man SA; Department of Pediatrics, Amphia Hospital, Breda, The Netherlands., Pfundt R; Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands; and., Azmani Z; Department of Cell Biology, and.; Center for Biomics, Erasmus MC, Rotterdam, The Netherlands., Brouwer RWW; Department of Cell Biology, and.; Center for Biomics, Erasmus MC, Rotterdam, The Netherlands., Bauer DE; Division of Hematology/Oncology, Department of Pediatric Oncology, Boston Children's Hospital, Boston, MA.; Dana-Farber Cancer Institute, Boston, MA.; Harvard Stem Cell Institute, Boston, MA.; Broad Institute, Boston, MA.; Department of Pediatrics, Harvard Medical School, Boston, MA., van den Hout MCGN; Department of Cell Biology, and.; Center for Biomics, Erasmus MC, Rotterdam, The Netherlands., van IJcken WFJ; Department of Cell Biology, and.; Center for Biomics, Erasmus MC, Rotterdam, The Netherlands., Philipsen S; Academic Center for Hemoglobinopathies and Rare Anemias.; Department of Cell Biology, and.

Publikováno v: Blood advances [Blood Adv] 2021 May 11; Vol. 5 (9), pp. 2339-2349.

Exome Sequencing Analysis Identifies Rare Variants in ATM and RPL8 That Are Associated With Shorter Telomere Length.

Autor: van der Spek A; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.; SkylineDx B.V., Rotterdam, Netherlands., Warner SC; Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom., Broer L; Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom., Vojinovic D; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands., Ahmad S; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands., Arp PP; Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands., Brouwer RWW; Center for Biomics, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands., Denniff M; Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom., van den Hout MCGN; Center for Biomics, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands., van Rooij JGJ; Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.; Department of Neurology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands., Kraaij R; Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands., van IJcken WFJ; Center for Biomics, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom., Ikram MA; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands., Uitterlinden AG; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.; Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands., Codd V; Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom., Amin N; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom., van Duijn CM; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

Publikováno v: Frontiers in genetics [Front Genet] 2020 Apr 30; Vol. 11, pp. 337. Date of Electronic Publication: 2020 Apr 30 (Print Publication: 2020).