Metabolites of the plasticizer di (2-ethylhexyl) phthalate in urine samples of workers in polyvinylchloride processing industries

Autor: van den Broek Ph, Arends Am, de Lepper Aj, P. T. Henderson, Frans J. Jongeneelen, Hubert Dirven, Nordkamp Hh

Publikováno v: International Archives of Occupational and Environmental Health. 64:549-554

Little is known about occupational exposure to the plasticizer di(2-ethylhexyl)phthalate (CAS number 117-81-7), a compound widely used in polyvinylchloride (PVC) plastics. We have studied the uptake of DEHP in workers by determining the concentration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0daa7774271414ded45ce35ae10d8b48
https://doi.org/10.1007/bf00517699

Uremic Solutes in Chronic Kidney Disease and Their Role in Progression.

Autor: van den Brand JA; Department of Nephrology, Radboud Institute of Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Mutsaers HA; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen, The Netherlands., van Zuilen AD; Department of Nephrology and Hypertension, University Medical Centre Utrecht, Utrecht, The Netherlands., Blankestijn PJ; Department of Nephrology and Hypertension, University Medical Centre Utrecht, Utrecht, The Netherlands., van den Broek PH; Department of Pharmacology and Toxicology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Russel FG; Department of Pharmacology and Toxicology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Masereeuw R; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands., Wetzels JF; Department of Nephrology, Radboud Institute of Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

Publikováno v: PloS one [PLoS One] 2016 Dec 29; Vol. 11 (12), pp. e0168117. Date of Electronic Publication: 2016 Dec 29 (Print Publication: 2016).

Bioengineered kidney tubules efficiently excrete uremic toxins.

Autor: Jansen J; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.; Physiology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.; Department of Pediatrics, Radboud university medical center, Nijmegen, The Netherlands.; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands., Fedecostante M; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.; Physiology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.; Department of Pediatrics, Radboud university medical center, Nijmegen, The Netherlands.; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands., Wilmer MJ; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., Peters JG; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., Kreuser UM; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., van den Broek PH; Department of Pharmacology and Toxicology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., Mensink RA; Cluster for Molecular Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands., Boltje TJ; Cluster for Molecular Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands., Stamatialis D; Department of Biomaterials Science and Technology, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, The Netherlands., Wetzels JF; Nephrology, Radboud university medical center, Nijmegen, The Netherlands., van den Heuvel LP; Department of Pediatrics, Radboud university medical center, Nijmegen, The Netherlands.; Department of Pediatric Nephrology &Growth and Regeneration, Catholic University Leuven, Leuven, Belgium., Hoenderop JG; Physiology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., Masereeuw R; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands.

Publikováno v: Scientific reports [Sci Rep] 2016 May 31; Vol. 6, pp. 26715. Date of Electronic Publication: 2016 May 31.

The Influence of Dietary Protein Intake on Mammalian Tryptophan and Phenolic Metabolites.

Autor: Poesen R; Department of Microbiology and Immunology, Division of Nephrology, University Hospitals Leuven, Leuven, Belgium., Mutsaers HA; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands; Department of Physiology and Pediatrics, Radboud University Medical Center, Nijmegen, The Netherlands; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen, The Netherlands., Windey K; Translational Research for Gastrointestinal Disorders (Targid) and Leuven Food Science and Nutrition Research Centre (LFoRCe), University of Leuven, Leuven, Belgium., van den Broek PH; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., Verweij V; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., Augustijns P; Department of Pharmaceutical and Pharmacological Sciences, Drug Delivery and Disposition, University of Leuven, Leuven, Belgium., Kuypers D; Department of Microbiology and Immunology, Division of Nephrology, University Hospitals Leuven, Leuven, Belgium., Jansen J; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands; Department of Physiology and Pediatrics, Radboud University Medical Center, Nijmegen, The Netherlands., Evenepoel P; Department of Microbiology and Immunology, Division of Nephrology, University Hospitals Leuven, Leuven, Belgium., Verbeke K; Translational Research for Gastrointestinal Disorders (Targid) and Leuven Food Science and Nutrition Research Centre (LFoRCe), University of Leuven, Leuven, Belgium., Meijers B; Department of Microbiology and Immunology, Division of Nephrology, University Hospitals Leuven, Leuven, Belgium., Masereeuw R; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands.

Publikováno v: PloS one [PLoS One] 2015 Oct 15; Vol. 10 (10), pp. e0140820. Date of Electronic Publication: 2015 Oct 15 (Print Publication: 2015).

Proximal tubular efflux transporters involved in renal excretion of p-cresyl sulfate and p-cresyl glucuronide: Implications for chronic kidney disease pathophysiology.

Autor: Mutsaers HA; Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands; Department of Physiology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands; Department of Pediatrics, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen, The Netherlands., Caetano-Pinto P; Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, The Netherlands., Seegers AE; Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., Dankers AC; Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., van den Broek PH; Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., Wetzels JF; Department of Nephrology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., van den Brand JA; Department of Nephrology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., van den Heuvel LP; Department of Pediatrics, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands; Department of Pediatrics, Catholic University Leuven, Leuven, Belgium., Hoenderop JG; Department of Physiology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., Wilmer MJ; Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands., Masereeuw R; Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, The Netherlands. Electronic address: r.masereeuw@uu.nl.

Publikováno v: Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2015 Oct; Vol. 29 (7), pp. 1868-77. Date of Electronic Publication: 2015 Jul 26.