Výsledky vyhledávání - "van den Bosch MT"

Akademický článek

Epigenetic Regulation of F2RL3 Associates With Myocardial Infarction and Platelet Function.

Autor: Corbin LJ; MRC Integrative Epidemiology Unit at University of Bristol, United Kingdom (L.J.C., L.F., A.G., L.P., M.R.M., C.R., J.L.M., G.D.S., N.J.T.).; Population Health Sciences, Bristol Medical School (L.J.C., A.E.T., K.T., L.F., A.G., L.P., C.R., J.L.M., G.D.S., N.J.T.), University of Bristol, United Kingdom., White SJ; Department of Life Sciences, Manchester Metropolitan University, United Kingdom (S.J.W.)., Taylor AE; Population Health Sciences, Bristol Medical School (L.J.C., A.E.T., K.T., L.F., A.G., L.P., C.R., J.L.M., G.D.S., N.J.T.), University of Bristol, United Kingdom.; NIHR Biomedical Research Centre at the University Hospitals Bristol NHS Foundation Trust and the University of Bristol, United Kingdom (A.E.T.)., Williams CM; Population Health Sciences, Bristol Medical School (L.J.C., A.E.T., K.T., L.F., A.G., L.P., C.R., J.L.M., G.D.S., N.J.T.), University of Bristol, United Kingdom.; School of Physiology, Pharmacology and Neuroscience (C.M.W., M.T.v.d.B., A.W.P.), University of Bristol, United Kingdom., Taylor K; Population Health Sciences, Bristol Medical School (L.J.C., A.E.T., K.T., L.F., A.G., L.P., C.R., J.L.M., G.D.S., N.J.T.), University of Bristol, United Kingdom., van den Bosch MT; School of Physiology, Pharmacology and Neuroscience (C.M.W., M.T.v.d.B., A.W.P.), University of Bristol, United Kingdom., Teasdale JE; Translational Health Sciences, Bristol Medical School (J.E.T., M.J., M.B.), University of Bristol, United Kingdom., Jones M; Translational Health Sciences, Bristol Medical School (J.E.T., M.J., M.B.), University of Bristol, United Kingdom., Bond M; Translational Health Sciences, Bristol Medical School (J.E.T., M.J., M.B.), University of Bristol, United Kingdom., Harper MT; Department of Pharmacology, University of Cambridge, Tennis Court Road (M.T.H., G.G.J.H.)., Falk L; MRC Integrative Epidemiology Unit at University of Bristol, United Kingdom (L.J.C., L.F., A.G., L.P., M.R.M., C.R., J.L.M., G.D.S., N.J.T.).; Population Health Sciences, Bristol Medical School (L.J.C., A.E.T., K.T., L.F., A.G., L.P., C.R., J.L.M., G.D.S., N.J.T.), University of Bristol, United Kingdom., Groom A; MRC Integrative Epidemiology Unit at University of Bristol, United Kingdom (L.J.C., L.F., A.G., L.P., M.R.M., C.R., J.L.M., G.D.S., N.J.T.).; Population Health Sciences, Bristol Medical School (L.J.C., A.E.T., K.T., L.F., A.G., L.P., C.R., J.L.M., G.D.S., N.J.T.), University of Bristol, United Kingdom., Hazell GGJ; Department of Pharmacology, University of Cambridge, Tennis Court Road (M.T.H., G.G.J.H.)., Paternoster L; MRC Integrative Epidemiology Unit at University of Bristol, United Kingdom (L.J.C., L.F., A.G., L.P., M.R.M., C.R., J.L.M., G.D.S., N.J.T.).; Population Health Sciences, Bristol Medical School (L.J.C., A.E.T., K.T., L.F., A.G., L.P., C.R., J.L.M., G.D.S., N.J.T.), University of Bristol, United Kingdom., Munafò MR; MRC Integrative Epidemiology Unit at University of Bristol, United Kingdom (L.J.C., L.F., A.G., L.P., M.R.M., C.R., J.L.M., G.D.S., N.J.T.).; UK Centre for Tobacco and Alcohol Studies and School of Experimental Psychology (M.R.M.), University of Bristol, United Kingdom., Nordestgaard BG; Department of Clinical Biochemistry, Herlev and Gentofte Hospital (B.G.N., S.E.B.), Copenhagen University Hospital, Denmark.; The Copenhagen City Heart Study, Frederiksberg Hospital (B.G.N., A.T.-H., S.E.B.), Copenhagen University Hospital, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (B.G.N., A.T.-H., S.E.B.)., Tybjærg-Hansen A; The Copenhagen City Heart Study, Frederiksberg Hospital (B.G.N., A.T.-H., S.E.B.), Copenhagen University Hospital, Denmark.; Department of Clinical Biochemistry, Rigshospitalet (A.T.-H.), Copenhagen University Hospital, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (B.G.N., A.T.-H., S.E.B.)., Bojesen SE; Department of Clinical Biochemistry, Herlev and Gentofte Hospital (B.G.N., S.E.B.), Copenhagen University Hospital, Denmark.; The Copenhagen City Heart Study, Frederiksberg Hospital (B.G.N., A.T.-H., S.E.B.), Copenhagen University Hospital, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (B.G.N., A.T.-H., S.E.B.)., Relton C; MRC Integrative Epidemiology Unit at University of Bristol, United Kingdom (L.J.C., L.F., A.G., L.P., M.R.M., C.R., J.L.M., G.D.S., N.J.T.).; Population Health Sciences, Bristol Medical School (L.J.C., A.E.T., K.T., L.F., A.G., L.P., C.R., J.L.M., G.D.S., N.J.T.), University of Bristol, United Kingdom., Min JL; MRC Integrative Epidemiology Unit at University of Bristol, United Kingdom (L.J.C., L.F., A.G., L.P., M.R.M., C.R., J.L.M., G.D.S., N.J.T.).; Population Health Sciences, Bristol Medical School (L.J.C., A.E.T., K.T., L.F., A.G., L.P., C.R., J.L.M., G.D.S., N.J.T.), University of Bristol, United Kingdom., Davey Smith G; MRC Integrative Epidemiology Unit at University of Bristol, United Kingdom (L.J.C., L.F., A.G., L.P., M.R.M., C.R., J.L.M., G.D.S., N.J.T.).; Population Health Sciences, Bristol Medical School (L.J.C., A.E.T., K.T., L.F., A.G., L.P., C.R., J.L.M., G.D.S., N.J.T.), University of Bristol, United Kingdom., Mumford AD; School of Cellular and Molecular Medicine (A.D.M.), University of Bristol, United Kingdom., Poole AW; School of Physiology, Pharmacology and Neuroscience (C.M.W., M.T.v.d.B., A.W.P.), University of Bristol, United Kingdom., Timpson NJ; MRC Integrative Epidemiology Unit at University of Bristol, United Kingdom (L.J.C., L.F., A.G., L.P., M.R.M., C.R., J.L.M., G.D.S., N.J.T.).; Population Health Sciences, Bristol Medical School (L.J.C., A.E.T., K.T., L.F., A.G., L.P., C.R., J.L.M., G.D.S., N.J.T.), University of Bristol, United Kingdom.

Publikováno v: Circulation research [Circ Res] 2022 Feb 04; Vol. 130 (3), pp. 384-400. Date of Electronic Publication: 2022 Jan 11.

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Akademický článek

Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis.

Autor: Agbani EO; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, Bristol, United Kingdom.; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Williams CM; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, Bristol, United Kingdom., Li Y; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, Bristol, United Kingdom., van den Bosch MT; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, Bristol, United Kingdom., Moore SF; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, Bristol, United Kingdom., Mauroux A; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, Bristol, United Kingdom., Hodgson L; Wolfson Bioimaging Facility, University of Bristol, Biomedical Sciences Building, Bristol, United Kingdom., Verkman AS; Departments of Medicine and Physiology, University of California San Francisco, San Francisco, California, USA., Hers I; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, Bristol, United Kingdom., Poole AW; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, Bristol, United Kingdom.

Publikováno v: JCI insight [JCI Insight] 2018 May 17; Vol. 3 (10). Date of Electronic Publication: 2018 May 17 (Print Publication: 2018).

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Akademický článek

Integrin α IIb β 3 outside-in signaling.

Autor: Durrant TN; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, United Kingdom., van den Bosch MT; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, United Kingdom., Hers I; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, United Kingdom.

Publikováno v: Blood [Blood] 2017 Oct 05; Vol. 130 (14), pp. 1607-1619. Date of Electronic Publication: 2017 Aug 09.

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Akademický článek

Platelet-Associated Matrix Metalloproteinases Regulate Thrombus Formation and Exert Local Collagenolytic Activity.

Autor: Mastenbroek TG; From the Department of Biochemistry (T.G.M., M.A.H.F., R.M.W.K., M.T.J.v.d.B., F.S., P.E.J.v.d.M., J.M.E.M.C.) and Synapse BV (R.M.W.K.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; School of Physiology and Pharmacology (M.T.J.v.d.B.) and School of Clinical Sciences (J.L.J.), University of Bristol, Bristol, United Kingdom; Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium (L.D.G., L.M.); Department of Haematology, University of Cambridge, Cambridge, United Kingdom (C.B., C.G.); and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom (C.B., C.G.)., Feijge MA; From the Department of Biochemistry (T.G.M., M.A.H.F., R.M.W.K., M.T.J.v.d.B., F.S., P.E.J.v.d.M., J.M.E.M.C.) and Synapse BV (R.M.W.K.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; School of Physiology and Pharmacology (M.T.J.v.d.B.) and School of Clinical Sciences (J.L.J.), University of Bristol, Bristol, United Kingdom; Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium (L.D.G., L.M.); Department of Haematology, University of Cambridge, Cambridge, United Kingdom (C.B., C.G.); and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom (C.B., C.G.)., Kremers RM; From the Department of Biochemistry (T.G.M., M.A.H.F., R.M.W.K., M.T.J.v.d.B., F.S., P.E.J.v.d.M., J.M.E.M.C.) and Synapse BV (R.M.W.K.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; School of Physiology and Pharmacology (M.T.J.v.d.B.) and School of Clinical Sciences (J.L.J.), University of Bristol, Bristol, United Kingdom; Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium (L.D.G., L.M.); Department of Haematology, University of Cambridge, Cambridge, United Kingdom (C.B., C.G.); and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom (C.B., C.G.)., van den Bosch MT; From the Department of Biochemistry (T.G.M., M.A.H.F., R.M.W.K., M.T.J.v.d.B., F.S., P.E.J.v.d.M., J.M.E.M.C.) and Synapse BV (R.M.W.K.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; School of Physiology and Pharmacology (M.T.J.v.d.B.) and School of Clinical Sciences (J.L.J.), University of Bristol, Bristol, United Kingdom; Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium (L.D.G., L.M.); Department of Haematology, University of Cambridge, Cambridge, United Kingdom (C.B., C.G.); and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom (C.B., C.G.)., Swieringa F; From the Department of Biochemistry (T.G.M., M.A.H.F., R.M.W.K., M.T.J.v.d.B., F.S., P.E.J.v.d.M., J.M.E.M.C.) and Synapse BV (R.M.W.K.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; School of Physiology and Pharmacology (M.T.J.v.d.B.) and School of Clinical Sciences (J.L.J.), University of Bristol, Bristol, United Kingdom; Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium (L.D.G., L.M.); Department of Haematology, University of Cambridge, Cambridge, United Kingdom (C.B., C.G.); and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom (C.B., C.G.)., De Groef L; From the Department of Biochemistry (T.G.M., M.A.H.F., R.M.W.K., M.T.J.v.d.B., F.S., P.E.J.v.d.M., J.M.E.M.C.) and Synapse BV (R.M.W.K.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; School of Physiology and Pharmacology (M.T.J.v.d.B.) and School of Clinical Sciences (J.L.J.), University of Bristol, Bristol, United Kingdom; Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium (L.D.G., L.M.); Department of Haematology, University of Cambridge, Cambridge, United Kingdom (C.B., C.G.); and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom (C.B., C.G.)., Moons L; From the Department of Biochemistry (T.G.M., M.A.H.F., R.M.W.K., M.T.J.v.d.B., F.S., P.E.J.v.d.M., J.M.E.M.C.) and Synapse BV (R.M.W.K.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; School of Physiology and Pharmacology (M.T.J.v.d.B.) and School of Clinical Sciences (J.L.J.), University of Bristol, Bristol, United Kingdom; Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium (L.D.G., L.M.); Department of Haematology, University of Cambridge, Cambridge, United Kingdom (C.B., C.G.); and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom (C.B., C.G.)., Bennett C; From the Department of Biochemistry (T.G.M., M.A.H.F., R.M.W.K., M.T.J.v.d.B., F.S., P.E.J.v.d.M., J.M.E.M.C.) and Synapse BV (R.M.W.K.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; School of Physiology and Pharmacology (M.T.J.v.d.B.) and School of Clinical Sciences (J.L.J.), University of Bristol, Bristol, United Kingdom; Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium (L.D.G., L.M.); Department of Haematology, University of Cambridge, Cambridge, United Kingdom (C.B., C.G.); and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom (C.B., C.G.)., Ghevaert C; From the Department of Biochemistry (T.G.M., M.A.H.F., R.M.W.K., M.T.J.v.d.B., F.S., P.E.J.v.d.M., J.M.E.M.C.) and Synapse BV (R.M.W.K.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; School of Physiology and Pharmacology (M.T.J.v.d.B.) and School of Clinical Sciences (J.L.J.), University of Bristol, Bristol, United Kingdom; Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium (L.D.G., L.M.); Department of Haematology, University of Cambridge, Cambridge, United Kingdom (C.B., C.G.); and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom (C.B., C.G.)., Johnson JL; From the Department of Biochemistry (T.G.M., M.A.H.F., R.M.W.K., M.T.J.v.d.B., F.S., P.E.J.v.d.M., J.M.E.M.C.) and Synapse BV (R.M.W.K.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; School of Physiology and Pharmacology (M.T.J.v.d.B.) and School of Clinical Sciences (J.L.J.), University of Bristol, Bristol, United Kingdom; Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium (L.D.G., L.M.); Department of Haematology, University of Cambridge, Cambridge, United Kingdom (C.B., C.G.); and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom (C.B., C.G.)., van der Meijden PE; From the Department of Biochemistry (T.G.M., M.A.H.F., R.M.W.K., M.T.J.v.d.B., F.S., P.E.J.v.d.M., J.M.E.M.C.) and Synapse BV (R.M.W.K.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; School of Physiology and Pharmacology (M.T.J.v.d.B.) and School of Clinical Sciences (J.L.J.), University of Bristol, Bristol, United Kingdom; Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium (L.D.G., L.M.); Department of Haematology, University of Cambridge, Cambridge, United Kingdom (C.B., C.G.); and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom (C.B., C.G.)., Cosemans JM; From the Department of Biochemistry (T.G.M., M.A.H.F., R.M.W.K., M.T.J.v.d.B., F.S., P.E.J.v.d.M., J.M.E.M.C.) and Synapse BV (R.M.W.K.), Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; School of Physiology and Pharmacology (M.T.J.v.d.B.) and School of Clinical Sciences (J.L.J.), University of Bristol, Bristol, United Kingdom; Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium (L.D.G., L.M.); Department of Haematology, University of Cambridge, Cambridge, United Kingdom (C.B., C.G.); and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom (C.B., C.G.). judith.cosemans@maastrichtuniversity.nl.

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2015 Dec; Vol. 35 (12), pp. 2554-61. Date of Electronic Publication: 2015 Oct 15.

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Akademický článek

Coordinated Membrane Ballooning and Procoagulant Spreading in Human Platelets.

Autor: Agbani EO; From School of Physiology & Pharmacology, University of Bristol, United Kingdom (E.O.A., M.T.J.v.d.B., E.B., C.M.W., I.H., A.W.P.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, The Netherlands (N.J.A.M., J.M.E.M.C., J.W.M.H.); and Welsh Blood Service and Arthur Bloom Haemophilia Centre, School of Medicine, Cardiff University, United Kingdom (P.W.C.). a.poole@bristol.ac.uk e.agbani@bristol.ac.uk., van den Bosch MT; From School of Physiology & Pharmacology, University of Bristol, United Kingdom (E.O.A., M.T.J.v.d.B., E.B., C.M.W., I.H., A.W.P.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, The Netherlands (N.J.A.M., J.M.E.M.C., J.W.M.H.); and Welsh Blood Service and Arthur Bloom Haemophilia Centre, School of Medicine, Cardiff University, United Kingdom (P.W.C.)., Brown E; From School of Physiology & Pharmacology, University of Bristol, United Kingdom (E.O.A., M.T.J.v.d.B., E.B., C.M.W., I.H., A.W.P.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, The Netherlands (N.J.A.M., J.M.E.M.C., J.W.M.H.); and Welsh Blood Service and Arthur Bloom Haemophilia Centre, School of Medicine, Cardiff University, United Kingdom (P.W.C.)., Williams CM; From School of Physiology & Pharmacology, University of Bristol, United Kingdom (E.O.A., M.T.J.v.d.B., E.B., C.M.W., I.H., A.W.P.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, The Netherlands (N.J.A.M., J.M.E.M.C., J.W.M.H.); and Welsh Blood Service and Arthur Bloom Haemophilia Centre, School of Medicine, Cardiff University, United Kingdom (P.W.C.)., Mattheij NJ; From School of Physiology & Pharmacology, University of Bristol, United Kingdom (E.O.A., M.T.J.v.d.B., E.B., C.M.W., I.H., A.W.P.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, The Netherlands (N.J.A.M., J.M.E.M.C., J.W.M.H.); and Welsh Blood Service and Arthur Bloom Haemophilia Centre, School of Medicine, Cardiff University, United Kingdom (P.W.C.)., Cosemans JM; From School of Physiology & Pharmacology, University of Bristol, United Kingdom (E.O.A., M.T.J.v.d.B., E.B., C.M.W., I.H., A.W.P.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, The Netherlands (N.J.A.M., J.M.E.M.C., J.W.M.H.); and Welsh Blood Service and Arthur Bloom Haemophilia Centre, School of Medicine, Cardiff University, United Kingdom (P.W.C.)., Collins PW; From School of Physiology & Pharmacology, University of Bristol, United Kingdom (E.O.A., M.T.J.v.d.B., E.B., C.M.W., I.H., A.W.P.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, The Netherlands (N.J.A.M., J.M.E.M.C., J.W.M.H.); and Welsh Blood Service and Arthur Bloom Haemophilia Centre, School of Medicine, Cardiff University, United Kingdom (P.W.C.)., Heemskerk JW; From School of Physiology & Pharmacology, University of Bristol, United Kingdom (E.O.A., M.T.J.v.d.B., E.B., C.M.W., I.H., A.W.P.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, The Netherlands (N.J.A.M., J.M.E.M.C., J.W.M.H.); and Welsh Blood Service and Arthur Bloom Haemophilia Centre, School of Medicine, Cardiff University, United Kingdom (P.W.C.)., Hers I; From School of Physiology & Pharmacology, University of Bristol, United Kingdom (E.O.A., M.T.J.v.d.B., E.B., C.M.W., I.H., A.W.P.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, The Netherlands (N.J.A.M., J.M.E.M.C., J.W.M.H.); and Welsh Blood Service and Arthur Bloom Haemophilia Centre, School of Medicine, Cardiff University, United Kingdom (P.W.C.)., Poole AW; From School of Physiology & Pharmacology, University of Bristol, United Kingdom (E.O.A., M.T.J.v.d.B., E.B., C.M.W., I.H., A.W.P.; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University of Maastricht, The Netherlands (N.J.A.M., J.M.E.M.C., J.W.M.H.); and Welsh Blood Service and Arthur Bloom Haemophilia Centre, School of Medicine, Cardiff University, United Kingdom (P.W.C.). a.poole@bristol.ac.uk e.agbani@bristol.ac.uk.

Publikováno v: Circulation [Circulation] 2015 Oct 13; Vol. 132 (15), pp. 1414-24. Date of Electronic Publication: 2015 Sep 01.

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Report

Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4-deficient platelets.

Autor: Harper MT; School of Physiology and Pharmacology, University of Bristol, Bristol, United Kingdom., van den Bosch MT; School of Physiology and Pharmacology, University of Bristol, Bristol, United Kingdom., Hers I; School of Physiology and Pharmacology, University of Bristol, Bristol, United Kingdom., Poole AW; School of Physiology and Pharmacology, University of Bristol, Bristol, United Kingdom.

Publikováno v: Blood [Blood] 2015 May 07; Vol. 125 (19), pp. 3034-6.

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Akademický článek

Cytohesin-2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP-ribosylation factor 6.

Autor: van den Bosch MT; School of Physiology and Pharmacology, University of Bristol, Bristol, UK., Poole AW, Hers I

Publikováno v: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2014 May; Vol. 12 (5), pp. 726-35.

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Akademický článek

Dual regulation of glycogen synthase kinase 3 (GSK3)α/β by protein kinase C (PKC)α and Akt promotes thrombin-mediated integrin αIIbβ3 activation and granule secretion in platelets.

Autor: Moore SF; School of Physiology and Pharmacology, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom., van den Bosch MT, Hunter RW, Sakamoto K, Poole AW, Hers I

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2013 Feb 08; Vol. 288 (6), pp. 3918-28. Date of Electronic Publication: 2012 Dec 13.

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Akademický článek

Absence of platelet phenotype in mice lacking the motor protein myosin Va.

Autor: Harper MT; School of Physiology and Pharmacology, University of Bristol, Bristol, United Kingdom., van den Bosch MT, Hers I, Poole AW

Publikováno v: PloS one [PLoS One] 2013; Vol. 8 (1), pp. e53239. Date of Electronic Publication: 2013 Jan 18.

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