Synthesis of Cluster Galactosides with High Affinity for the Hepatic Asialoglycoprotein Receptor

Autor: Roelen Hc, van Berkel Tj, Beuting Dm, van de Marel Ga, E.A.L. Biessen, van Boom Jh

Publikováno v: Journal of Medicinal Chemistry. 38:1538-1546

High-affinity ligands for the asialoglycoprotein receptor, which is uniquely localized on the parenchymal liver cell and recognizes oligoantennary galactosides, might be utilized as homing device to specifically target drugs or genes to parenchymal l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd66f5e92e05d77587600530317fad9
https://doi.org/10.1021/jm00009a014

Synthesis of cluster galactosides with high affinity for the hepatic asialoglycoprotein receptor.

Autor: Biessen EA; Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research, Sylvius Laboratories, University of Leiden, The Netherlands., Beuting DM, Roelen HC, van de Marel GA, van Boom JH, van Berkel TJ

Publikováno v: Journal of medicinal chemistry [J Med Chem] 1995 Apr 28; Vol. 38 (9), pp. 1538-46.