Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Chickens with a Truncated Light Chain Transgene Express Single-Domain H Chain-Only Antibodies.

Autor: Leighton PA; OmniAb, Emeryville, CA., Ching K, Reynolds K; OmniAb, Emeryville, CA., Vuong CN; OmniAb, Emeryville, CA., Zeng B; OmniAb, Emeryville, CA., Zhang Y; OmniAb, Emeryville, CA., Gupta A; OmniAb, Emeryville, CA., Morales J, Rivera GS; OmniAb, Emeryville, CA., Srivastava DB; OmniAb, Emeryville, CA., Cotter R, Pedersen D; OmniAb, Emeryville, CA., Collarini E; OmniAb, Emeryville, CA., Izquierdo S; OmniAb, Emeryville, CA., van de Lavoir MC; OmniAb, Emeryville, CA., Harriman W; OmniAb, Emeryville, CA.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2024 Jun 01; Vol. 212 (11), pp. 1744-1753.

Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets.

Autor: Ching KH; a Ligand Pharmaceuticals Incorporated , 5980 Horton Street, Suite 405, Emeryville , CA , USA., Collarini EJ; a Ligand Pharmaceuticals Incorporated , 5980 Horton Street, Suite 405, Emeryville , CA , USA., Abdiche YN; b Carterra, Inc. , 825 N. 300 W., Suite C309, Salt Lake City , UT , USA., Bedinger D; b Carterra, Inc. , 825 N. 300 W., Suite C309, Salt Lake City , UT , USA., Pedersen D; a Ligand Pharmaceuticals Incorporated , 5980 Horton Street, Suite 405, Emeryville , CA , USA., Izquierdo S; a Ligand Pharmaceuticals Incorporated , 5980 Horton Street, Suite 405, Emeryville , CA , USA., Harriman R; a Ligand Pharmaceuticals Incorporated , 5980 Horton Street, Suite 405, Emeryville , CA , USA., Zhu L; a Ligand Pharmaceuticals Incorporated , 5980 Horton Street, Suite 405, Emeryville , CA , USA., Etches RJ; a Ligand Pharmaceuticals Incorporated , 5980 Horton Street, Suite 405, Emeryville , CA , USA., van de Lavoir MC; a Ligand Pharmaceuticals Incorporated , 5980 Horton Street, Suite 405, Emeryville , CA , USA., Harriman WD; a Ligand Pharmaceuticals Incorporated , 5980 Horton Street, Suite 405, Emeryville , CA , USA., Leighton PA; a Ligand Pharmaceuticals Incorporated , 5980 Horton Street, Suite 405, Emeryville , CA , USA.

Publikováno v: MAbs [MAbs] 2018 Jan; Vol. 10 (1), pp. 71-80. Date of Electronic Publication: 2017 Nov 02.

Expression of heavy chain-only antibodies can support B-cell development in light chain knockout chickens.

Autor: Schusser B; Reproductive Biotechnology, Technische Universität München, WZW Center of Life Science, Freising-Weihenstephan, Germany., Collarini EJ; Crystal Bioscience Inc, Emeryville, CA, USA., Pedersen D; Crystal Bioscience Inc, Emeryville, CA, USA., Yi H; Crystal Bioscience Inc, Emeryville, CA, USA., Ching K; Crystal Bioscience Inc, Emeryville, CA, USA., Izquierdo S; Crystal Bioscience Inc, Emeryville, CA, USA., Thoma T; Reproductive Biotechnology, Technische Universität München, WZW Center of Life Science, Freising-Weihenstephan, Germany., Lettmann S; Department of Veterinary Science, Institute for Animal Physiology, Ludwig-Maximilians-Universitaet Muenchen, Munich, Germany., Kaspers B; Department of Veterinary Science, Institute for Animal Physiology, Ludwig-Maximilians-Universitaet Muenchen, Munich, Germany., Etches RJ; Crystal Bioscience Inc, Emeryville, CA, USA., van de Lavoir MC; Crystal Bioscience Inc, Emeryville, CA, USA., Harriman W; Crystal Bioscience Inc, Emeryville, CA, USA., Leighton PA; Crystal Bioscience Inc, Emeryville, CA, USA. pal@crystalbioscience.com.

Publikováno v: European journal of immunology [Eur J Immunol] 2016 Sep; Vol. 46 (9), pp. 2137-48. Date of Electronic Publication: 2016 Aug 02.

Inserting random and site-specific changes into the genome of chickens.

Autor: Collarini E; Crystal Bioscience Inc., 5980 Horton Street Suite 405, Emeryville, CA 94608., Leighton P; Crystal Bioscience Inc., 5980 Horton Street Suite 405, Emeryville, CA 94608., Pedersen D; Crystal Bioscience Inc., 5980 Horton Street Suite 405, Emeryville, CA 94608., Harriman B; Crystal Bioscience Inc., 5980 Horton Street Suite 405, Emeryville, CA 94608., Jacob R; Crystal Bioscience Inc., 5980 Horton Street Suite 405, Emeryville, CA 94608., Mettler-Izquierdo S; Crystal Bioscience Inc., 5980 Horton Street Suite 405, Emeryville, CA 94608., Yi H; Crystal Bioscience Inc., 5980 Horton Street Suite 405, Emeryville, CA 94608., van de Lavoir MC; Crystal Bioscience Inc., 5980 Horton Street Suite 405, Emeryville, CA 94608., Etches RJ; Crystal Bioscience Inc., 5980 Horton Street Suite 405, Emeryville, CA 94608 RobEtches@CrystalBioscience.com.

Publikováno v: Poultry science [Poult Sci] 2015 Apr; Vol. 94 (4), pp. 799-803.