An interconnected data infrastructure to support large-scale rare disease research.

Autor: Johansson LF; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Laurie S; Centro Nacional de Análisis Genómico, C/Baldiri Reixac 4, 08028, Barcelona, Spain.; Universitat de Barcelona (UB), Gran Via de les Corts Catalanes, 585, L'Eixample, 08007, Barcelona, Spain., Spalding D; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CV10 1SD, UK., Gibson S; Department of Genetics, Genomics and Cancer Sciences, University of Leicester, University Road, Leicester, Leicester, LE1 7RH, UK., Ruvolo D; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Thomas C; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CV10 1SD, UK., Piscia D; Centro Nacional de Análisis Genómico, C/Baldiri Reixac 4, 08028, Barcelona, Spain.; Universitat de Barcelona (UB), Gran Via de les Corts Catalanes, 585, L'Eixample, 08007, Barcelona, Spain., de Andrade F; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Been G; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Bijlsma M; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Brunner H; Department of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, Nijmegen, 6525 GA, The Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, P.O.Box 9103, Nijmegen, 6500 HD, The Netherlands.; Department of Clinical Genetics, Maastricht University Medical Centre, P. Debyelaan 25, Maastricht, 6229 HX, The Netherlands., Cimerman S; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Dizjikan FY; Department of Genetics, Genomics and Cancer Sciences, University of Leicester, University Road, Leicester, Leicester, LE1 7RH, UK., Ellwanger K; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstraße 7, Tübingen 72076, Germany., Fernandez M; Centro Nacional de Análisis Genómico, C/Baldiri Reixac 4, 08028, Barcelona, Spain.; Universitat de Barcelona (UB), Gran Via de les Corts Catalanes, 585, L'Eixample, 08007, Barcelona, Spain., Freeberg M; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CV10 1SD, UK., van de Geijn GJ; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Kanninga R; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Maddi V; Department of Genetics, Genomics and Cancer Sciences, University of Leicester, University Road, Leicester, Leicester, LE1 7RH, UK., Mehtarizadeh M; Department of Genetics, Genomics and Cancer Sciences, University of Leicester, University Road, Leicester, Leicester, LE1 7RH, UK., Neerincx P; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Ossowski S; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstraße 7, Tübingen 72076, Germany.; Institute for Bioinformatics and Medical Informatics (IBMI), University of Tübingen, Geschwister-Scholl-Platz, Tübingen 72074, Germany., Rath A; INSERM, US-14 Orphanet, 96 rue Didot, Paris 75014, France., Roelofs-Prins D; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Stok-Benjamins M; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., van der Velde KJ; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Veal C; Department of Genetics, Genomics and Cancer Sciences, University of Leicester, University Road, Leicester, Leicester, LE1 7RH, UK., van der Vries G; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Wadsley M; Department of Genetics, Genomics and Cancer Sciences, University of Leicester, University Road, Leicester, Leicester, LE1 7RH, UK., Warren G; Department of Genetics, Genomics and Cancer Sciences, University of Leicester, University Road, Leicester, Leicester, LE1 7RH, UK., Zurek B; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstraße 7, Tübingen 72076, Germany., Keane T; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CV10 1SD, UK., Graessner H; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstraße 7, Tübingen 72076, Germany.; Centre for Rare Diseases, University of Tübingen, Geschäftsstelle Eisenbahnstraße 63, Tübingen 72072, Germany., Beltran S; Centro Nacional de Análisis Genómico, C/Baldiri Reixac 4, 08028, Barcelona, Spain.; Departament de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona (UB), Diagonal, 643, 08028, Barcelona, Spain., Swertz MA; Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, P.O. Box 30001, Groningen, 9700 RB, The Netherlands., Brookes AJ; Department of Genetics, Genomics and Cancer Sciences, University of Leicester, University Road, Leicester, Leicester, LE1 7RH, UK.

Publikováno v: GigaScience [Gigascience] 2024 Jan 02; Vol. 13.

MOLGENIS research: advanced bioinformatics data software for non-bioinformaticians.

Autor: van der Velde KJ; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Imhann F; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands.; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Charbon B; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Pang C; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., van Enckevort D; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Slofstra M; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Barbieri R; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands.; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Alberts R; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands.; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Hendriksen D; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Kelpin F; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., de Haan M; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., de Boer T; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Haakma S; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Stroomberg C; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Scholtens S; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., van de Geijn GJ; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Festen EAM; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands.; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands., Swertz MA; Genomics Coordination Center, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands.

Publikováno v: Bioinformatics (Oxford, England) [Bioinformatics] 2019 Mar 15; Vol. 35 (6), pp. 1076-1078.

Leucocyte-bound apolipoprotein B in the circulation is inversely associated with the presence of clinical and subclinical atherosclerosis.

Autor: de Vries MA; Department of Internal Medicine, Center for Diabetes and Vascular Medicine, St. Franciscus Gasthuis, Rotterdam, The Netherlands., Klop B; Department of Internal Medicine, Center for Diabetes and Vascular Medicine, St. Franciscus Gasthuis, Rotterdam, The Netherlands., van der Meulen N; Department of Internal Medicine, Center for Diabetes and Vascular Medicine, St. Franciscus Gasthuis, Rotterdam, The Netherlands., van de Geijn GJ; Department of Clinical Chemistry, St. Franciscus Gasthuis, Rotterdam, The Netherlands., Prinzen L; Department of Clinical Chemistry, St. Franciscus Gasthuis, Rotterdam, The Netherlands., van der Zwan E; Department of Clinical Chemistry, St. Franciscus Gasthuis, Rotterdam, The Netherlands., Birnie E; Department of Statistics and Education, St. Franciscus Gasthuis, Rotterdam, The Netherlands., Cohen Tervaert JW; Department of Statistics and Education, St. Franciscus Gasthuis, Rotterdam, The Netherlands., Liem AH; Department of Cardiology, St. Franciscus Gasthuis, Rotterdam, The Netherlands., de Herder WW; Department of Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands., Castro Cabezas M; Department of Internal Medicine, Center for Diabetes and Vascular Medicine, St. Franciscus Gasthuis, Rotterdam, The Netherlands.

Publikováno v: European journal of clinical investigation [Eur J Clin Invest] 2016 Aug; Vol. 46 (8), pp. 690-7. Date of Electronic Publication: 2016 Jul 08.

In vivo evidence for chylomicrons as mediators of postprandial inflammation.

Autor: de Vries MA; Department of Internal Medicine, Center for Diabetes and Vascular Medicine, Rotterdam, The Netherlands., Klop B; Department of Internal Medicine, Center for Diabetes and Vascular Medicine, Rotterdam, The Netherlands., Alipour A; Department of Internal Medicine, Center for Diabetes and Vascular Medicine, Rotterdam, The Netherlands., van de Geijn GJ; Department of Clinical Chemistry, Rotterdam, The Netherlands., Prinzen L; Department of Clinical Chemistry, Rotterdam, The Netherlands., Liem AH; Department of Cardiology, Sint Franciscus Gasthuis, Rotterdam, The Netherlands., Valdivielso P; Internal Medicine Unit, Hospital Virgen de la Victoria and Department of Medicine and Dermatology, IBIMA, University Málaga, Campus de Teatinos s/n, 29010 Málaga, Spain., Rioja Villodres J; Internal Medicine Unit, Hospital Virgen de la Victoria and Department of Medicine and Dermatology, IBIMA, University Málaga, Campus de Teatinos s/n, 29010 Málaga, Spain., Ramírez-Bollero J; Internal Medicine Unit, Hospital Virgen de la Victoria and Department of Medicine and Dermatology, IBIMA, University Málaga, Campus de Teatinos s/n, 29010 Málaga, Spain., Castro Cabezas M; Department of Internal Medicine, Center for Diabetes and Vascular Medicine, Rotterdam, The Netherlands. Electronic address: m.castrocabezas@sfg.nl.

Publikováno v: Atherosclerosis [Atherosclerosis] 2015 Dec; Vol. 243 (2), pp. 540-5. Date of Electronic Publication: 2015 Oct 23.

Effect of bariatric surgery on asthma control, lung function and bronchial and systemic inflammation in morbidly obese subjects with asthma.

Autor: van Huisstede A; Department of Pulmonology, Sint Franciscus Gasthuis, Rotterdam, The Netherlands., Rudolphus A; Department of Pulmonology, Sint Franciscus Gasthuis, Rotterdam, The Netherlands., Castro Cabezas M; Department of Internal Medicine, Sint Franciscus Gasthuis, Rotterdam, The Netherlands., Biter LU; Department of Surgery, Sint Franciscus Gasthuis, Rotterdam, The Netherlands., van de Geijn GJ; Department of Clinical Chemistry, Sint Franciscus Gasthuis, Rotterdam, The Netherlands., Taube C; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Hiemstra PS; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Braunstahl GJ; Department of Pulmonology, Sint Franciscus Gasthuis, Rotterdam, The Netherlands.

Publikováno v: Thorax [Thorax] 2015 Jul; Vol. 70 (7), pp. 659-67. Date of Electronic Publication: 2015 Apr 30.