Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression

Autor: Komor, MA, Wit, M, Berg, J, de Kemp, SRM, Delis-van Diemen, PM, Bolijn, AS, Tijssen, M, Schelfhorst, T, Piersma, SR, Chiasserini, D, Sanders, J, Rausch, C, Hoogstrate, Youri, Stubbs, Andrew, Jong, M, Jenster, Guido, Carvalho, B, Meijer, GA, Jimenez, CR, Fijneman, RJA, Dits, Natasja, Böttcher, René, Hiemstra, AC, Ylstra, B, Sie, D, Broek, E, van Grieken, N, Meer, D, Pepers, F, Caldenhoven, E, Janssen, B, van Workum, W, van Lieshout, S, Bangma, C.H., van Leenders, Arno, van de Werken, Harmen

Publikováno v: International Journal of Cancer, 146(7), 1979-1992. Wiley-Liss Inc.
Komor, M A, de Wit, M, van den Berg, J, Martens de Kemp, S R, Delis-van Diemen, P M, Bolijn, A S, Tijssen, M, Schelfhorst, T, Piersma, S R, Chiasserini, D, Sanders, J, Rausch, C, Hoogstrate, Y, Stubbs, A P, de Jong, M, Jenster, G, Carvalho, B, Meijer, G A, Jimenez, C R, Fijneman, R J A & In collaboration with the NGS-ProToCol Consortium 2020, ' Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression ', International Journal of Cancer, vol. 146, no. 7, pp. 1979-1992 . https://doi.org/10.1002/ijc.32627
International Journal of Cancer

Removal of colorectal adenomas is an effective strategy to reduce colorectal cancer (CRC) mortality rates. However, as only a minority of adenomas progress to cancer, such strategies may lead to overtreatment. The present study aimed to characterize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f18edb5b8a61777493b094f6c33b9d
https://doi.org/10.1002/ijc.32627

Paternally InheritedIGF2Mutation and Growth Restriction

Autor: Büttel Hm, Matthias Begemann, Gijs W. E. Santen, Gerhard Binder, Zirn B, Schweizer R, Lukas Soellner, Thomas Eggermann, van Workum W, Elisa Wirthgen

Publikováno v: New England Journal of Medicine, 373(4), 349-356

In humans, mutations in IGF1 or IGF1R cause intrauterine and postnatal growth restriction; however, data on mutations in IGF2, encoding insulin-like growth factor (IGF) II, are lacking. We report an IGF2 variant (c.191C→A, p.Ser64Ter) with evidence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8122e4373bf5f6d2fcdacaf4c39a4147
https://doi.org/10.1056/nejmoa1415227

Illumina Sequencing Technology as a Method of Identifying T-DNA Insertion Loci in Activation-Tagged Arabidopsis thaliana Plants

Autor: Polko, J.K., Temanni, M.R., van Zanten, M., van Workum, W., Iburg, Sven, Pierik, R., Voesenek, L.A.C.J., Peeters, A.J.M., Plant Ecophysiology, Sub Plant Ecophysiology, Sub Molecular Plant Physiology

Publikováno v: Molecular Plant, 5(4), 948. Cell Press

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ea697ddab68b20369462f9e32b6c31

Kinome profiling of Arabidopsis using arrays of kinase consensus substrates

Autor: Ritsema, T., Joore, J., van Workum, W., Pieterse, C.M.J., Phytopathology, Dep Biologie

Publikováno v: Plant Methods, 3(3). BioMed Central

Background Kinome profiling aims at the parallel analysis of kinase activities in a cell. Novel developed arrays containing consensus substrates for kinases are used to assess those kinase activities. The arrays described in this paper were already u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::d11eb8c1d53abca5e446adbd25a8a407
https://dspace.library.uu.nl/handle/1874/388027

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