Molecular hallmarks of heterochronic parabiosis at single-cell resolution

Autor: Pálovics, Róbert, Keller, Andreas, Schaum, Nicholas, Tan, Weilun, Fehlmann, Tobias, Borja, Michael, Kern, Fabian, Bonanno, Liana, Calcuttawala, Kruti, Webber, James, McGeever, Aaron, Almanzar, Nicole, Antony, Jane, Baghel, Ankit S., Bakerman, Isaac, Bansal, Ishita, Barres, Ben A., Beachy, Philip A., Berdnik, Daniela, Bilen, Biter, Brownfield, Douglas, Cain, Corey, Chan, Charles K. F., Chen, Michelle B., Clarke, Michael F., Conley, Stephanie D., Demers, Aaron, Demir, Kubilay, de Morree, Antoine, Divita, Tessa, du Bois, Haley, Ebadi, Hamid, Espinoza, F. Hernán, Fish, Matt, Gan, Qiang, George, Benson M., Gillich, Astrid, Gòmez-Sjöberg, Rafael, Green, Foad, Genetiano, Geraldine, Gu, Xueying, Gulati, Gunsagar S., Hahn, Oliver, Haney, Michael Seamus, Hang, Yan, Harris, Lincoln, He, Mu, Hosseinzadeh, Shayan, Huang, Albin, Huang, Kerwyn Casey, Iram, Tal, Isobe, Taichi, Ives, Feather, Jones, Robert C., Kao, Kevin S., Karnam, Guruswamy, Kershner, Aaron M., Khoury, Nathalie, Kim, Seung K., Kiss, Bernhard M., Kong, William, Krasnow, Mark A., Kumar, Maya E., Kuo, Christin S., Lam, Jonathan, Lee, Davis P., Lee, Song E., Lehallier, Benoit, Leventhal, Olivia, Li, Guang, Li, Qingyun, Liu, Ling, Lo, Annie, Lu, Wan-Jin, Lugo-Fagundo, Maria F., Manjunath, Anoop, May, Andrew P., Maynard, Ashley, McKay, Marina, McNerney, M. Windy, Merrill, Bryan, Metzger, Ross J., Mignardi, Marco, Min, Dullei, Nabhan, Ahmad N., Ng, Katharine M., Nguyen, Patricia K., Noh, Joseph, Nusse, Roel, Patkar, Rasika, Peng, Weng Chuan, Penland, Lolita, Pollard, Katherine, Puccinelli, Robert, Qi, Zhen, Rando, Thomas A., Rulifson, Eric J., Segal, Joe M., Sikandar, Shaheen S., Sinha, Rahul, Sit, Rene V., Sonnenburg, Justin, Staehli, Daniel, Szade, Krzysztof, Tan, Michelle, Tato, Cristina, Tellez, Krissie, Torrez Dulgeroff, Laughing Bear, Travaglini, Kyle J., Tropini, Carolina, Tsui, Margaret, Waldburger, Lucas, Wang, Bruce M., van Weele, Linda J., Weinberg, Kenneth, Weissman, Irving L., Wosczyna, Michael N., Wu, Sean M., Xiang, Jinyi, Xue, Soso, Yamauchi, Kevin A., Yang, Andrew C., Yerra, Lakshmi P., Youngyunpipatkul, Justin, Yu, Brian, Zanini, Fabio, Zardeneta, Macy E., Zee, Alexander, Zhao, Chunyu, Zhang, Fan, Zhang, Hui, Zhang, Martin Jinye, Zhou, Lu, Zou, James, Luo, Jian, Pisco, Angela Oliveira, Karkanias, Jim, Neff, Norma F., Darmanis, Spyros, Quake, Stephen R., Wyss-Coray, Tony

Publikováno v: Nature
Pálovics, R, Keller, A, Schaum, N, Tan, W, Fehlmann, T, Borja, M, Kern, F, Bonanno, L, Calcuttawala, K, Webber, J, McGeever, A, Tabula Muris Consortium, Luo, J, Pisco, A O, Karkanias, J, Neff, N F, Darmanis, S, Quake, S R & Wyss-Coray, T 2022, ' Molecular hallmarks of heterochronic parabiosis at single-cell resolution ', Nature, vol. 603, no. 7900, pp. 309-314 . https://doi.org/10.1038/s41586-022-04461-2

The ability to slow or reverse biological ageing would have major implications for mitigating disease risk and maintaining vitality1. Although an increasing number of interventions show promise for rejuvenation2, their effectiveness on disparate cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd4792daef95a04ce6dabca873901af
https://doi.org/10.1038/s41586-022-04461-2

Mesenchymal tumor cells drive adaptive resistance of Trp53^-/- breast tumor cells to inactivated mutant Kras.

Autor: van Weele, Linda J., Djomehri, Sabra I., Cai, Shang, Antony, Jane, Sikandar, Shaheen S., Qian, Dalong, Ho, William H. D., West, Robert B., Scheeren, Ferenc A., Clarke, Michael F.

Publikováno v: Molecular Oncology; Sep2022, Vol. 16 Issue 17, p3128-3145, 18p

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

Autor: Schaum, Nicholas, Karkanias, Jim, Neff, Norma F., May, Andrew P., Quake, Stephen R., Wyss-Coray, Tony, Darmanis, Spyros, Batson, Joshua, Botvinnik, Olga, Chen, Michelle B., Chen, Steven, Green, Foad, Jones, Robert C., Maynard, Ashley, Penland, Lolita, Pisco, Angela Oliveira, Sit, Rene V., Stanley, Geoffrey M., Webber, James T., Zanini, Fabio, Baghel, Ankit S., Bakerman, Isaac, Bansal, Ishita, Berdnik, Daniela, Bilen, Biter, Brownfield, Douglas, Cain, Corey, Cho, Min, Cirolia, Giana, Conley, Stephanie D., Demers, Aaron, Demir, Kubilay, Morree, Antoinette, Divita, Tessa, Bois, Haley, Torrez Dulgeroff, Laughing Bear, Ebadi, Hamid, Espinoza, F. Hernán, Fish, Matt, Gan, Qiang, George, Benson M., Gillich, Astrid, Genetiano, Geraldine, Gu, Xueying, Gulati, Gunsagar S., Hang, Yan, Hosseinzadeh, Shayan, Huang, Albin, Iram, Tal, Isobe, Taichi, Ives, Feather, Kao, Kevin S., Karnam, Guruswamy, Kershner, Aaron M., Kiss, Bernhard M., Kong, William, Kumar, Maya E., Lam, Jonathan Y., Lee, Davis P., Lee, Song E., Li, Guang, Li, Qingyun, Liu, Ling, Lo, Annie, Lu, Wan-Jin, Manjunath, Anoop, May, Kaia L., May, Oliver L., McKay, Marina, Metzger, Ross J., Mignardi, Marco, Min, Dullei, Nabhan, Ahmad N., Ng, Katherine M., Noh, Joseph, Patkar, Rasika, Peng, Weng Chuan, Puccinelli, Robert, Rulifson, Eric J., Sikandar, Shaheen S., Sinha, Rahul, Szade, Krzysztof, Tan, Weilun, Tato, Cristina, Tellez, Krissie, Travaglini, Kyle J., Tropini, Carolina, Waldburger, Lucas, van Weele, Linda J., Wosczyna, Michael N., Xiang, Jinyi, Xue, Soso, Youngyunpipatkul, Justin, Zardeneta, Macy E., Zhang, Fan, Zhou, Lu, Castro, Paola, Croote, Derek, DeRisi, Joseph L., Kuo, Christin S., Lehallier, Benoit, Nguyen, Patricia K., Tan, Serena Y., Wang, Bruce M., Yousef, Hanadie, Beachy, Philip A., Chan, Charles K. F., Huang, Kerwyn Casey, Weinberg, Kenneth, Barres, Ben A., Clarke, Michael F., Kim, Seung K., Krasnow, Mark A., Nusse, Roel, Rando, Thomas A., Sonnenburg, Justin, Weissman, Irving L., Wu, Sean M.

Publikováno v: Nature. 562:367-372

Here we present a compendium of single-cell transcriptomic data from the model organism Mus musculus that comprises more than 100,000 cells from 20 organs and tissues. These data represent a new resource for cell biology, reveal gene expression in po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ec78863850994a7e6817d91ba36a25
https://doi.org/10.1038/s41586-018-0590-4

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