Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model

Autor: Rockx, Barry, Kuiken, Thijs, Herfst, Sander, Bestebroer, Theo, Lamers, Mart M., Munnink, Bas B. Oude, de Meulder, Dennis, van Amerongen, Geert, van den Brand, Judith, Okba, Nisreen M. A., Schipper, Debby, van Run, Peter, Leijten, Lonneke, Sikkema, Reina, Verschoor, Ernst, Verstrepen, Babs, Bogers, Willy, Langermans, Jan, Drosten, Christian, van Vlissingen, Martje Fentener, Fouchier, Ron, de Swart, Rik, Koopmans, Marion, Haagmans, Bart L., VPDC pathologie, dPB I&I, dPB CR, AISS LAS/3'R Centre ULS

Publikováno v: Science, 368(6494), 1012. American Association for the Advancement of Science
Science, 368(6494), 1012-1015. American Association for the Advancement of Science
Science (New York, N.y.)
Science

Coronavirus in nonhuman primates We urgently need vaccines and drug treatments for coronavirus disease 2019 (COVID-19). Even under these extreme circumstances, we must have animal models for rigorous testing of new strategies. Rockx et al. have under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50407d59ea5f87e41b8bcbce8d9245b
https://doi.org/10.1126/science.abb7314

A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection

Autor: Li, Tingting, Cai, Hongmin, Yao, Hebang, Zhou, Bingjie, Zhang, Ning, van Vlissingen, Martje Fentener, Kuiken, Thijs, Han, Wenyu, GeurtsvanKessel, Corine H, Gong, Yuhuan, Zhao, Yapei, Shen, Quan, Qin, Wenming, Tian, Xiao-Xu, Peng, Chao, Lai, Yanling, Wang, Yanxing, Hutter, Cedric A J, Kuo, Shu-Ming, Bao, Juan, Liu, Caixuan, Wang, Yifan, Richard, Audrey S, Raoul, Hervé, Lan, Jiaming, Seeger, Markus A, Cong, Yao, Rockx, Barry, Wong, Gary, Bi, Yuhai, et al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408492e58fe6482c0bcf77a3643b01a5

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Approaches to animal research project evaluation in Europe after implementation of Directive 2010/63/EU

Autor: Guillén, Javier, Robinson, Sally, Decelle, Thierry, Exner, Cornelia, van Vlissingen, Martje Fentener

Publikováno v: Lab Animal; December 2014, Vol. 44 Issue: 1 p23-31, 9p

A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection.

Autor: Li T; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), Shanghai, China., Cai H; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), Shanghai, China., Yao H; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), Shanghai, China., Zhou B; University of CAS, Beijing, China.; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai CAS, Shanghai, China., Zhang N; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), CAS, Beijing, China., van Vlissingen MF; Erasmus Laboratory Animal Science Center, Erasmus University Medical Center, Rotterdam, Netherlands.; European Research Infrastructure on Highly Pathogenic Agents (ERINHA-AISBL), Paris, France., Kuiken T; European Research Infrastructure on Highly Pathogenic Agents (ERINHA-AISBL), Paris, France.; Department of Viroscience, Erasmus University Medical Center, Rotterdam, Netherlands., Han W; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), Shanghai, China.; University of CAS, Beijing, China., GeurtsvanKessel CH; European Research Infrastructure on Highly Pathogenic Agents (ERINHA-AISBL), Paris, France.; Department of Viroscience, Erasmus University Medical Center, Rotterdam, Netherlands., Gong Y; University of CAS, Beijing, China.; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), CAS, Beijing, China., Zhao Y; University of CAS, Beijing, China.; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai CAS, Shanghai, China., Shen Q; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), CAS, Beijing, China., Qin W; National Facility for Protein Science in Shanghai, Shanghai Advanced Research Institute (Zhangjiang Laboratory), CAS, Shanghai, China., Tian XX; National Facility for Protein Science in Shanghai, Shanghai Advanced Research Institute (Zhangjiang Laboratory), CAS, Shanghai, China., Peng C; National Facility for Protein Science in Shanghai, Shanghai Advanced Research Institute (Zhangjiang Laboratory), CAS, Shanghai, China., Lai Y; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), Shanghai, China.; University of CAS, Beijing, China., Wang Y; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), Shanghai, China., Hutter CAJ; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland., Kuo SM; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai CAS, Shanghai, China., Bao J; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), Shanghai, China., Liu C; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), Shanghai, China.; University of CAS, Beijing, China., Wang Y; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), Shanghai, China.; University of CAS, Beijing, China., Richard AS; European Research Infrastructure on Highly Pathogenic Agents (ERINHA-AISBL), Paris, France., Raoul H; European Research Infrastructure on Highly Pathogenic Agents (ERINHA-AISBL), Paris, France., Lan J; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai CAS, Shanghai, China., Seeger MA; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland., Cong Y; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), Shanghai, China., Rockx B; European Research Infrastructure on Highly Pathogenic Agents (ERINHA-AISBL), Paris, France.; Department of Viroscience, Erasmus University Medical Center, Rotterdam, Netherlands., Wong G; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai CAS, Shanghai, China. garyckwong@ips.ac.cn.; Département de microbiologie-infectiologie et d'immunologie, Université Laval, Québec, QC, Canada. garyckwong@ips.ac.cn., Bi Y; University of CAS, Beijing, China. beeyh@im.ac.cn.; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), CAS, Beijing, China. beeyh@im.ac.cn., Lavillette D; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai CAS, Shanghai, China. dlaville@ips.ac.cn.; Pasteurien College, Soochow University, Jiangsu, China. dlaville@ips.ac.cn., Li D; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences (CAS), Shanghai, China. dianfan.li@sibcb.ac.cn.

Publikováno v: Nature communications [Nat Commun] 2021 Jul 30; Vol. 12 (1), pp. 4635. Date of Electronic Publication: 2021 Jul 30.