Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial

Autor: Davidson, Aj, Frawley, G, Hardy, P, Arnup, Sj, Schuster, T, Lee, K, Hunt, Rw, Stargatt, R, Sheppard, S, Ormond, Gd, Hartmann, Pl, Takagi, Mj, Malarbi, S, Doyle, M, Ragg, P, Backstrom, M, Costi, D, von Ungern Sternberg, Bs, Wilton, Nc, Knottenbelt, G, Disma, NICOLA MASSIMO, Montobbio, G, Mameli, L, Tuo, P, Girbaldi, G, PINI PRATO, Alessio, Mattioli, Girolamo, Wolfler, A, Izzo, F, Salvo, I, Sonzogni, V, Locatelli, Bg, Khotcholava, M, de Graaff, Jc, van Gool, Jt, Numan, Sc, van Veldhuijzen, D, Kalkman, Cj, van Baar, Al, Steenis, Lj, Hagenaars, Jh, Absalom, Ar, Hoekstra, Fm, Volkers, M, Withington, D, Furue, K, Gaudreault, J, Mccann, Me, Berde, C, Soriano, S, Young, V, Sethna, N, Kovatsis, P, Cravero, J, Bellinger, D, Marmor, J, Lynn, A, Ivanova, I, Hunyady, A, Verma, S, Polaner, D, Thomas, J, Mueller, M, Haret, D, Szmuk, P, Steiner, J, Kravitz, B, Surantham, S, Hays, S, Taenzer, A, Maxwell, L, Williams, Rk, Morton, Ns, Bell, G, Dorris, L, Adey, C, Pownall, J, Bagshaw, O, Chisakuta, A, Eissa, A, Stoddart, P, Davis, A, Myles, P, Withngton, De, Degraaff, Jc, Bellinger, Dc, Wolf, A, Mcintosh, N, Carlin, J, Leslie, K, de Lima, J, Hammer, G, Field, D, Gebski, V, Tibboel, D.

Publikováno v: The Lancet, 387(10015), 239. Lancet Publishing Group
The Lancet, 387(10015), 239-250. ELSEVIER SCIENCE INC
The Lancet, 387(10015), 239. Elsevier Limited

Background Preclinical data suggest that general anaesthetics affect brain development. There is mixed evidence from cohort studies that young children exposed to anaesthesia can have an increased risk of poor neurodevelopmental outcome. We aimed to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e8a18f3d6b0e8518d7e05027ec1409
https://doi.org/10.1016/s0140-6736(15)00608-x