Aberrant PRDM2 methylation as an early event in serrated lesions destined to evolve into microsatellite-instable colorectal cancers.

Autor: van Toledo DE; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, location Academic Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology and Metabolism, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam University Medical Centers, Location Academic Medical Center, Amsterdam, The Netherlands., Bleijenberg AG; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, location Academic Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology and Metabolism, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam University Medical Centers, Location Academic Medical Center, Amsterdam, The Netherlands., Venema A; Department of Human Genetics, Epigenetics of disease, Amsterdam Gastroenterology Endocrinology and Metabolism, Amsterdam University Medical Centers, Location Academic Medical Center, Amsterdam, The Netherlands., de Wit MJ; Department of Pathology, Amsterdam, Amsterdam University Medical Centers, Location Academic Medical Center, The Netherlands., van Eeden S; Department of Pathology, Amsterdam, Amsterdam University Medical Centers, Location Academic Medical Center, The Netherlands., Meijer GA; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Carvalho B; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Dekker E; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, location Academic Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology and Metabolism, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam University Medical Centers, Location Academic Medical Center, Amsterdam, The Netherlands., Henneman P; Department of Human Genetics, Epigenetics of disease, Amsterdam Gastroenterology Endocrinology and Metabolism, Amsterdam University Medical Centers, Location Academic Medical Center, Amsterdam, The Netherlands., IJspeert JE; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, location Academic Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology and Metabolism, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam University Medical Centers, Location Academic Medical Center, Amsterdam, The Netherlands., van Noesel CJ; Department of Pathology, Amsterdam, Amsterdam University Medical Centers, Location Academic Medical Center, The Netherlands.

Publikováno v: The journal of pathology. Clinical research [J Pathol Clin Res] 2024 Mar; Vol. 10 (2), pp. e348.