Tissue damaging toxins in snake venoms: mechanisms of action, pathophysiology and treatment strategies.

Autor: Bittenbinder MA; Naturalis Biodiversity Center, 2333 CR, Leiden, The Netherlands.; AIMMS, Division of BioAnalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081HV, Amsterdam, The Netherlands.; Centre for Analytical Sciences Amsterdam (CASA), 1098 XH, Amsterdam, The Netherlands., van Thiel J; Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, Liverpool, United Kingdom.; Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE, Leiden, The Netherlands.; Howard Hughes Medical Institute and Department of Biology, University of Maryland, College Park, MD, 20742, USA., Cardoso FC; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland, Australia.; Centre for Innovations in Peptide and Protein Science, The University of Queensland, St Lucia, Brisbane, Queensland, Australia., Casewell NR; Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, Liverpool, United Kingdom., Gutiérrez JM; Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, 11501, Costa Rica. jose.gutierrez@ucr.ac.cr., Kool J; AIMMS, Division of BioAnalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081HV, Amsterdam, The Netherlands. j.kool@vu.nl.; Centre for Analytical Sciences Amsterdam (CASA), 1098 XH, Amsterdam, The Netherlands. j.kool@vu.nl., Vonk FJ; Naturalis Biodiversity Center, 2333 CR, Leiden, The Netherlands.; AIMMS, Division of BioAnalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081HV, Amsterdam, The Netherlands.; Centre for Analytical Sciences Amsterdam (CASA), 1098 XH, Amsterdam, The Netherlands.

Publikováno v: Communications biology [Commun Biol] 2024 Mar 22; Vol. 7 (1), pp. 358. Date of Electronic Publication: 2024 Mar 22.

Distinct regulatory networks control toxin gene expression in elapid and viperid snakes.

Autor: Modahl CM; Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore. Cassandra.Modahl@lstmed.ac.uk.; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, U.K.. Cassandra.Modahl@lstmed.ac.uk., Han SX; Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore.; Fulcrum Therapeutics, Cambridge, MA, U.S.A., van Thiel J; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, U.K.; Institute of Biology Leiden, Leiden University, Leiden, The Netherlands., Vaz C; Human Development, Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Dunstan NL; Venom Supplies, Tanunda, South Australia, Australia., Frietze S; Department of Biomedical and Health Sciences, University of Vermont, Burlington, VT, U.S.A., Jackson TNW; Australian Venom Research Unit, Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, Australia., Mackessy SP; Department of Biological Sciences, University of Northern Colorado, Greeley, CO, U.S.A., Kini RM; Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore. dbskinim@nus.edu.sg.; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. dbskinim@nus.edu.sg.; Singapore Eye Research Institute, Singapore, Singapore. dbskinim@nus.edu.sg.; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, VA, U.S.A.. dbskinim@nus.edu.sg.

Publikováno v: BMC genomics [BMC Genomics] 2024 Feb 16; Vol. 25 (1), pp. 186. Date of Electronic Publication: 2024 Feb 16.

Highly Evolvable: Investigating Interspecific and Intraspecific Venom Variation in Taipans ( Oxyuranus spp.) and Brown Snakes ( Pseudonaja spp.).

Autor: van Thiel J; Division of Bioanalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.; Institute of Biology Leiden, Leiden University, 2333 BE Leiden, The Netherlands.; Naturalis Biodiversity Center, 2333 CR Leiden, The Netherlands., Alonso LL; Division of Bioanalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.; Centre for Analytical Sciences Amsterdam (CASA), 1012 WX Amsterdam, The Netherlands., Slagboom J; Division of Bioanalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.; Centre for Analytical Sciences Amsterdam (CASA), 1012 WX Amsterdam, The Netherlands., Dunstan N; Venom Supplies Pty. Ltd., Tanunda, SA 5352, Australia., Wouters RM; Institute of Biology Leiden, Leiden University, 2333 BE Leiden, The Netherlands., Modahl CM; Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., Vonk FJ; Division of Bioanalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.; Naturalis Biodiversity Center, 2333 CR Leiden, The Netherlands.; Centre for Analytical Sciences Amsterdam (CASA), 1012 WX Amsterdam, The Netherlands., Jackson TNW; Australian Venom Research Unit, Department of Pharmacology and Therapeutics, University of Melbourne, Parkville, VIC 3010, Australia., Kool J; Division of Bioanalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.; Centre for Analytical Sciences Amsterdam (CASA), 1012 WX Amsterdam, The Netherlands.

Publikováno v: Toxins [Toxins (Basel)] 2023 Jan 13; Vol. 15 (1). Date of Electronic Publication: 2023 Jan 13.

Intraspecific venom variation in the medically important puff adder (Bitis arietans): Comparative venom gland transcriptomics, in vitro venom activity and immunological recognition by antivenom.

Autor: Dawson, Charlotte A.^1,2 (AUTHOR) Charlotte.Dawson@lstmed.ac.uk, Bartlett, Keirah E.^1,2 (AUTHOR), Wilkinson, Mark C.^1,2 (AUTHOR), Ainsworth, Stuart^1,2,3 (AUTHOR), Albulescu, Laura-Oana^1,2 (AUTHOR), Kazandijan, Taline^1,2 (AUTHOR), Hall, Steven R.⁴ (AUTHOR), Westhorpe, Adam^1,2 (AUTHOR), Clare, Rachel^1,2 (AUTHOR), Wagstaff, Simon² (AUTHOR), Modahl, Cassandra M.^1,2,5 (AUTHOR), Harrison, Robert A.^1,2 (AUTHOR), Casewell, Nicholas R.^1,2 (AUTHOR)

Publikováno v: PLoS Neglected Tropical Diseases. 10/18/2024, Vol. 18 Issue 10, p1-22. 22p.

Convergent evolution of pain-inducing defensive venom components in spitting cobras.

Autor: Kazandjian TD; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., Petras D; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA.; Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093, USA., Robinson SD; Centre for Advanced Imaging, University of Queensland, St Lucia, QLD 4072, Australia.; Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD 4072, Australia., van Thiel J; Institute of Biology, University of Leiden, Leiden 2333BE, Netherlands., Greene HW; Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY 14853, USA., Arbuckle K; Department of Biosciences, College of Science, Swansea University, Swansea SA2 8PP, UK., Barlow A; School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK.; Molecular Ecology and Fisheries Genetics Laboratory, School of Natural Sciences, Bangor University, Bangor LL57 2UW, UK., Carter DA; Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD 4072, Australia., Wouters RM; Institute of Biology, University of Leiden, Leiden 2333BE, Netherlands., Whiteley G; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., Wagstaff SC; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.; Research Computing Unit, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., Arias AS; Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José 11501, Costa Rica., Albulescu LO; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., Plettenberg Laing A; Molecular Ecology and Fisheries Genetics Laboratory, School of Natural Sciences, Bangor University, Bangor LL57 2UW, UK., Hall C; Molecular Ecology and Fisheries Genetics Laboratory, School of Natural Sciences, Bangor University, Bangor LL57 2UW, UK., Heap A; Molecular Ecology and Fisheries Genetics Laboratory, School of Natural Sciences, Bangor University, Bangor LL57 2UW, UK., Penrhyn-Lowe S; Molecular Ecology and Fisheries Genetics Laboratory, School of Natural Sciences, Bangor University, Bangor LL57 2UW, UK., McCabe CV; School of Earth Sciences, University of Bristol, Bristol BS8 1RL, UK., Ainsworth S; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., da Silva RR; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA.; Núcleo de Pesquisa em Produtos Naturais e Sintéticos (NPPNS), Molecular Sciences Department, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil., Dorrestein PC; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA., Richardson MK; Institute of Biology, University of Leiden, Leiden 2333BE, Netherlands., Gutiérrez JM; Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José 11501, Costa Rica., Calvete JJ; Evolutionary and Translational Venomics Laboratory, Consejo Superior de Investigaciones Científicas, 46010 Valencia, Spain., Harrison RA; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., Vetter I; Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD 4072, Australia.; School of Pharmacy, University of Queensland, Woolloongabba, QLD 4102, Australia., Undheim EAB; Centre for Advanced Imaging, University of Queensland, St Lucia, QLD 4072, Australia.; Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD 4072, Australia.; Centre for Biodiversity Dynamics, Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway.; Centre for Ecological and Evolutionary Synthesis, Department of Biosciences, University of Oslo, Blindern, 0316 Oslo, Norway., Wüster W; Molecular Ecology and Fisheries Genetics Laboratory, School of Natural Sciences, Bangor University, Bangor LL57 2UW, UK., Casewell NR; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK. nicholas.casewell@lstmed.ac.uk.

Publikováno v: Science (New York, N.Y.) [Science] 2021 Jan 22; Vol. 371 (6527), pp. 386-390.