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A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase

Autor: Buchan, K.D., Prajsnar, T.K., Ogryzko, N.V., de Jong, N.W.M., van Gent, M., Kolata, J., Foster, S.J., Van Strijp, J.A.G., Renshaw, S.A.

The neutrophil enzyme myeloperoxidase (MPO) is a major enzyme made by neutrophils to generate antimicrobial and immunomodulatory compounds, notably hypochlorous acid (HOCl), amplifying their capacity for destroying pathogens and regulating inflammati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::02fe44d65bcb26b7b412cfc2fba89038
https://eprints.whiterose.ac.uk/145245/1/journal.pone.0215592.pdf

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Bovine Staphylococcus aureus Secretes the Leukocidin LukMF′ To Kill Migrating Neutrophils through CCR1

Autor: Vrieling, M., Koymans, K.J., Heesterbeek, D.A.C., Aerts, P.C., Rutten, V.P.M.G., de Haas, C.J.C., van Kessel, K.P.M., Koets, A.P., Nijland, R, van Strijp, J.A.G., Infection & Immunity, Risk Assessment, dI&I RA-I&I I&I, LS Immunologie, Sub Immunologie, LS Theoretische Epidemiologie

Publikováno v: mBio, Vol 6, Iss 3 (2015)
mBio, 6(3). American Society for Microbiology
MBio [E], 6(3). American Society for Microbiology
mBio 6 (2015) 3
mBio
mBio, 6(3)

Although Staphylococcus aureus is best known for infecting humans, bovine-specific strains are a major cause of mastitis in dairy cattle. The bicomponent leukocidin LukMF′, exclusively harbored by S. aureus of ruminant origin, is a virulence factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09c495d054eb47f6c8634eed57510bb
https://journals.asm.org/doi/10.1128/mBio.00335-15

Pseudomonas syringae evades host Immunity by degrading flagellin monomers with alkaline protease AprA

Autor: Pel, M.J.C., Van Dijken, A.J.H., Bardoel, B.W., Seidl, M.F, Van der Ent, S., Van Strijp, J.A.G.

Publikováno v: Molecular Plant-Microbe Interactions, 27, 603. The American Phytopathological Society

Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c2fa9a3626ec8841e3539e43948d3d39
https://dspace.library.uu.nl/handle/1874/294540