Increased interleukin (IL)-7R[alpha] expression in salivary glands of patients with primary Sjogren's syndrome is restricted to T cells and correlates with IL-7 expression, lymphocyte numbers and activity.

Autor: Bikker A, Kruize AA, Wenting M, Versnel MA, Bijlsma JW, Lafeber FP, van Roon JA

Publikováno v: Annals of the Rheumatic Diseases; Jun2012, Vol. 71 Issue 6, p1027-1033, 7p

Elevated expression of interleukin-7 receptor in inflamed joints mediates interleukin-7-induced immune activation in rheumatoid arthritis.

Autor: Hartgring SA, van Roon JA, Wijk MW, Jacobs KM, Jahangier ZN, Willis CR, Bijlsma JW, Lafeber FP

Publikováno v: Arthritis & Rheumatism; Sep2009, Vol. 60 Issue 9, p2595-2605, 11p

Leflunomide/hydroxychloroquine combination therapy targets type I IFN-associated proteins in patients with Sjögren's syndrome that show potential to predict and monitor clinical response.

Autor: Hamkour S; Department of Rheumatology and Clinical Immunology, Laboratory of Translational Immunology, UMC, Utrecht, The Netherlands., van der Heijden EH; Department of Rheumatology and Clinical Immunology, Laboratory of Translational Immunology, UMC, Utrecht, The Netherlands., Lopes AP; Department of Rheumatology and Clinical Immunology, Laboratory of Translational Immunology, UMC, Utrecht, The Netherlands., Blokland SLM; Department of Rheumatology and Clinical Immunology, Laboratory of Translational Immunology, UMC, Utrecht, The Netherlands., Bekker CPJ; Department of Rheumatology and Clinical Immunology, Laboratory of Translational Immunology, UMC, Utrecht, The Netherlands., Van Helden-Meeuwsen CG; Immunology, Erasmus Medical Center, Rotterdam, The Netherlands., Versnel MA; Immunology, Erasmus Medical Center, Rotterdam, The Netherlands., Kruize AA; Department of Rheumatology and Clinical Immunology, Utrecht University, Utrecht, The Netherlands., Radstake TR; Department of Rheumatology and Clinical Immunology, Laboratory of Translational Immunology, UMC, Utrecht, The Netherlands., Leavis HL; Department of Rheumatology and Clinical Immunology, Laboratory of Translational Immunology, UMC, Utrecht, The Netherlands., Hillen MR; Department of Rheumatology and Clinical Immunology, Laboratory of Translational Immunology, UMC, Utrecht, The Netherlands., van Roon JA; Department of Rheumatology and Clinical Immunology, Laboratory of Translational Immunology, UMC, Utrecht, The Netherlands J.vanRoon@umcutrecht.nl.

Publikováno v: RMD open [RMD Open] 2023 Aug; Vol. 9 (3).

Development and preliminary validation of the Sjögren's Tool for Assessing Response (STAR): a consensual composite score for assessing treatment effect in primary Sjögren's syndrome.

Autor: Seror R; Paris-Saclay University, INSERM UMR1184: Centre for Immunology of Viral Infections and Autoimmune Diseases, Le Kremlin-Bicetre, France raphaele.seror@aphp.fr.; Rheumatology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpitaux universitaires Paris-Sud - Hôpital Bicêtre, Le Kremlin-Bicêtre, France., Baron G; Assistance Publique Hôpitaux de Paris, Hôtel Dieu hospital, Paris, France.; Centre d'Epidémiologie Clinique, INSERM U1153, Faculté de Médecine, Université Paris Descartes, Paris, France., Camus M; Paris-Saclay University, INSERM UMR1184: Centre for Immunology of Viral Infections and Autoimmune Diseases, Le Kremlin-Bicetre, France.; Rheumatology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpitaux universitaires Paris-Sud - Hôpital Bicêtre, Le Kremlin-Bicêtre, France., Cornec D; Rhumatologie, CHU Brest, Brest, France.; Université de Brest, INSERM UMR 1227, LBAI, Brest, France., Perrodeau E; Assistance Publique Hôpitaux de Paris, Hôtel Dieu hospital, Paris, France.; Centre d'Epidémiologie Clinique, INSERM U1153, Faculté de Médecine, Université Paris Descartes, Paris, France., Bowman SJ; Rheumatology, University Hospitals Birmingham, Birmingham, UK.; Rheumatology, Milton Keynes University Hospital, Milton Keynes, UK.; University of Birmingham, Birmingham, UK., Bombardieri M; Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK., Bootsma H; Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Gottenberg JE; Rheumatology, University Hospital of Strasbourg, Strasbourg, France.; Université de Strasbourg, IBMC, CNRS, UPR3572, Strasbourg, France., Fisher B; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Birmingham, UK.; Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK., Hueber W; Novartis Pharma, Basel, Switzerland., van Roon JA; Immunology, Rheumatology and Clinical Immunology, Center of Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Devauchelle-Pensec V; Rhumatologie, CHU Brest, Brest, France.; Université de Brest, INSERM UMR 1227, LBAI, Brest, France., Gergely P; Novartis Institutes for BioMedical Research Basel, Basel, Switzerland., Mariette X; Paris-Saclay University, INSERM UMR1184: Centre for Immunology of Viral Infections and Autoimmune Diseases, Le Kremlin-Bicetre, France.; Rheumatology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpitaux universitaires Paris-Sud - Hôpital Bicêtre, Le Kremlin-Bicêtre, France., Porcher R; Assistance Publique Hôpitaux de Paris, Hôtel Dieu hospital, Paris, France.; Centre d'Epidémiologie Clinique, INSERM U1153, Faculté de Médecine, Université Paris Descartes, Paris, France.

Publikováno v: Annals of the rheumatic diseases [Ann Rheum Dis] 2022 Jul; Vol. 81 (7), pp. 979-989. Date of Electronic Publication: 2022 Apr 07.

Low RUNX3 expression alters dendritic cell function in patients with systemic sclerosis and contributes to enhanced fibrosis.

Autor: Affandi AJ; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Rheumatology Section, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA., Carvalheiro T; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Ottria A; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Broen JC; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Rheumatology Section, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA., Bossini-Castillo L; Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas (IPBLN-CSIC), Granada, Spain.; Department of Cellular Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Tieland RG; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Bon LV; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Rheumatology Section, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA., Chouri E; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Rossato M; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Biotechnology, University of Verona, Verona, Italy., Mertens JS; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands., Garcia S; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Pandit A; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., de Kroon LM; Rheumatology Section, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA., Christmann RB; Rheumatology Section, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA., Martin J; Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas (IPBLN-CSIC), Granada, Spain., van Roon JA; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Radstake TR; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands w.k.marut@umcutrecht.nl T.R.D.J.Radstake@umcutrecht.nl.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Rheumatology Section, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA., Marut W; Laboratory of Translational Immunology, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands w.k.marut@umcutrecht.nl T.R.D.J.Radstake@umcutrecht.nl.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Annals of the rheumatic diseases [Ann Rheum Dis] 2019 Sep; Vol. 78 (9), pp. 1249-1259. Date of Electronic Publication: 2019 May 24.