Výsledky vyhledávání - "van Puijvelde GHM"

Akademický článek

Immunoproteasomal Inhibition With ONX-0914 Attenuates Atherosclerosis and Reduces White Adipose Tissue Mass and Metabolic Syndrome in Mice.

Autor: Schaftenaar FH; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., van Dam AD; Division of Endocrinology, Department of Medicine, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, the Netherlands (A.D.D., P.C.N.R.)., de Bruin G; Department of Chemical Biology, Leiden Institute of Chemistry, the Netherlands (G.d.B., B.I.F.)., Depuydt MAC; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., de Mol J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Amersfoort J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Douna H; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Meijer M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Kröner MJ; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., van Santbrink PJ; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Bernabé Kleijn MNA; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., van Puijvelde GHM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Florea BI; Department of Chemical Biology, Leiden Institute of Chemistry, the Netherlands (G.d.B., B.I.F.)., Slütter B; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Foks AC; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Bot I; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Rensen PCN; Division of Endocrinology, Department of Medicine, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, the Netherlands (A.D.D., P.C.N.R.)., Kuiper J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.).

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2024 Jun; Vol. 44 (6), pp. 1346-1364. Date of Electronic Publication: 2024 Apr 25.

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Akademický článek

Tim-1 mucin domain-mutant mice display exacerbated atherosclerosis.

Autor: Douna H; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333CC, Leiden, the Netherlands., Smit V; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333CC, Leiden, the Netherlands., van Puijvelde GHM; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333CC, Leiden, the Netherlands., Kiss MG; Department of Laboratory Medicine, Medical University of Vienna, Vienna, 1090, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Binder CJ; Department of Laboratory Medicine, Medical University of Vienna, Vienna, 1090, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Bot L; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333CC, Leiden, the Netherlands., Kuchroo VK; Department of Neurology, Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA., Lichtman AH; Department of Pathology, Brigham and Women's Hospital, Boston, MA, 02115, USA., Kuiper J; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333CC, Leiden, the Netherlands., Foks AC; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333CC, Leiden, the Netherlands. Electronic address: a.c.foks@lacdr.leidenuniv.nl.

Publikováno v: Atherosclerosis [Atherosclerosis] 2022 Jul; Vol. 352, pp. 1-9. Date of Electronic Publication: 2022 May 21.

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Akademický článek

IFNγ-Stimulated B Cells Inhibit T Follicular Helper Cells and Protect Against Atherosclerosis.

Autor: Douna H; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, Netherlands., de Mol J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, Netherlands., Amersfoort J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, Netherlands., Schaftenaar FH; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, Netherlands., Kiss MG; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Suur BE; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, Netherlands., Kroner MJ; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, Netherlands., Binder CJ; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Bot I; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, Netherlands., Van Puijvelde GHM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, Netherlands., Kuiper J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, Netherlands., Foks AC; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, Netherlands.

Publikováno v: Frontiers in cardiovascular medicine [Front Cardiovasc Med] 2022 Feb 02; Vol. 9, pp. 781436. Date of Electronic Publication: 2022 Feb 02 (Print Publication: 2022).

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Akademický článek

Diet-induced dyslipidemia induces metabolic and migratory adaptations in regulatory T cells.

Autor: Amersfoort J; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Schaftenaar FH; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Douna H; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., van Santbrink PJ; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., van Puijvelde GHM; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Slütter B; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Foks AC; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Harms A; Division of Biomedicine and Systems Pharmacology, LACDR, Leiden University, Leiden, The Netherlands., Moreno-Gordaliza E; Division of Biomedicine and Systems Pharmacology, LACDR, Leiden University, Leiden, The Netherlands., Wang Y; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA., Hankemeier T; Division of Biomedicine and Systems Pharmacology, LACDR, Leiden University, Leiden, The Netherlands., Bot I; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Chi H; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA., Kuiper J; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2021 Apr 23; Vol. 117 (5), pp. 1309-1324.

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Akademický článek

Fluorescent small-molecule agonists as follicle-stimulating hormone receptor imaging tools.

Autor: Hoogendoorn S; Leiden Institute of Chemistry, Leiden University Einsteinweg 55 2300 RA Leiden The Netherlands Sascha.hoogendoorn@unige.ch h.s.overkleeft@lic.leidenuniv.nl., van Puijvelde GHM; Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2300 RA Leiden The Netherlands., van der Marel GA; Leiden Institute of Chemistry, Leiden University Einsteinweg 55 2300 RA Leiden The Netherlands Sascha.hoogendoorn@unige.ch h.s.overkleeft@lic.leidenuniv.nl., van Koppen CJ; ElexoPharm GmbH Im Stadtwald Building A1.2 66123 Saarbrücken Germany., Timmers CM; Byondis B.V. Microweg 22 6545 CM Nijmegen The Netherlands., Overkleeft HS; Leiden Institute of Chemistry, Leiden University Einsteinweg 55 2300 RA Leiden The Netherlands Sascha.hoogendoorn@unige.ch h.s.overkleeft@lic.leidenuniv.nl.

Publikováno v: RSC chemical biology [RSC Chem Biol] 2020 Aug 03; Vol. 1 (4), pp. 263-272. Date of Electronic Publication: 2020 Aug 03 (Print Publication: 2020).

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Akademický článek

B- and T-lymphocyte attenuator stimulation protects against atherosclerosis by regulating follicular B cells.

Autor: Douna H; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Amersfoort J; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Schaftenaar FH; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Kröner MJ; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Kiss MG; Department of Laboratory Medicine, Medical University of Vienna, Vienna 1090, Austria., Slütter B; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Depuydt MAC; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Bernabé Kleijn MNA; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Wezel A; Department of Surgery, HMC Westeinde, The Hague, The Netherlands., Smeets HJ; Department of Surgery, HMC Westeinde, The Hague, The Netherlands., Yagita H; Department of Immunology, Juntendo University School of Medicine, Tokyo 113-8421, Japan., Binder CJ; Department of Laboratory Medicine, Medical University of Vienna, Vienna 1090, Austria., Bot I; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., van Puijvelde GHM; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Kuiper J; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., Foks AC; Division of BioTherapeutics, LACDR, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2020 Feb 01; Vol. 116 (2), pp. 295-305.

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Akademický článek

Induction of HLA-A2 restricted CD8 T cell responses against ApoB100 peptides does not affect atherosclerosis in a humanized mouse model.

Autor: Schaftenaar FH; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands. f.h.schaftenaar@lacdr.leidenuniv.nl., Amersfoort J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Douna H; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Kröner MJ; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Foks AC; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Bot I; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Slütter BA; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., van Puijvelde GHM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Drijfhout JW; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands., Kuiper J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands. j.kuiper@lacdr.leidenuniv.nl.

Publikováno v: Scientific reports [Sci Rep] 2019 Nov 22; Vol. 9 (1), pp. 17391. Date of Electronic Publication: 2019 Nov 22.

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Akademický článek

Bidirectional effects of IL-10 ⁺ regulatory B cells in Ldlr ^-/- mice.

Autor: Douna H; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands. Electronic address: h.douna@lacdr.leidenuniv.nl., Amersfoort J; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands., Schaftenaar FH; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands., Kroon S; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands., van Puijvelde GHM; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands., Kuiper J; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands., Foks AC; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands.

Publikováno v: Atherosclerosis [Atherosclerosis] 2019 Jan; Vol. 280, pp. 118-125. Date of Electronic Publication: 2018 Nov 09.

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Akademický článek

Disruption of a CD1d-mediated interaction between mast cells and NKT cells aggravates atherosclerosis.

Autor: Kritikou E; Division of BioTherapeutics, LACDR, Leiden University, NL, the Netherlands. Electronic address: e.kritikou@lacdr.leidenuniv.nl., van Duijn J; Division of BioTherapeutics, LACDR, Leiden University, NL, the Netherlands., Nahon JE; Division of BioTherapeutics, LACDR, Leiden University, NL, the Netherlands., van der Heijden T; Division of BioTherapeutics, LACDR, Leiden University, NL, the Netherlands., Bouwman M; Division of BioTherapeutics, LACDR, Leiden University, NL, the Netherlands., Groeneveldt C; Division of BioTherapeutics, LACDR, Leiden University, NL, the Netherlands., Schaftenaar FH; Division of BioTherapeutics, LACDR, Leiden University, NL, the Netherlands., Kröner MJ; Division of BioTherapeutics, LACDR, Leiden University, NL, the Netherlands., Kuiper J; Division of BioTherapeutics, LACDR, Leiden University, NL, the Netherlands., van Puijvelde GHM; Division of BioTherapeutics, LACDR, Leiden University, NL, the Netherlands., Bot I; Division of BioTherapeutics, LACDR, Leiden University, NL, the Netherlands.

Publikováno v: Atherosclerosis [Atherosclerosis] 2019 Jan; Vol. 280, pp. 132-139. Date of Electronic Publication: 2018 Nov 14.

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Defective Autophagy in T Cells Impairs the Development of Diet-Induced Hepatic Steatosis and Atherosclerosis.

Autor: Amersfoort J; Division of BioTherapeutics, LACDR, Leiden University, Leiden, Netherlands., Douna H; Division of BioTherapeutics, LACDR, Leiden University, Leiden, Netherlands., Schaftenaar FH; Division of BioTherapeutics, LACDR, Leiden University, Leiden, Netherlands., Foks AC; Division of BioTherapeutics, LACDR, Leiden University, Leiden, Netherlands., Kröner MJ; Division of BioTherapeutics, LACDR, Leiden University, Leiden, Netherlands., van Santbrink PJ; Division of BioTherapeutics, LACDR, Leiden University, Leiden, Netherlands., van Puijvelde GHM; Division of BioTherapeutics, LACDR, Leiden University, Leiden, Netherlands., Bot I; Division of BioTherapeutics, LACDR, Leiden University, Leiden, Netherlands., Kuiper J; Division of BioTherapeutics, LACDR, Leiden University, Leiden, Netherlands.

Publikováno v: Frontiers in immunology [Front Immunol] 2018 Dec 12; Vol. 9, pp. 2937. Date of Electronic Publication: 2018 Dec 12 (Print Publication: 2018).

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