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CD8+ T-cells contribute to lesion stabilization in advanced atherosclerosis by limiting macrophage content and CD4+ T-cell responses.

Autor: van Duijn J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Room EE1.17, 2333 CC Leiden, the Netherlands., Kritikou E; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Room EE1.17, 2333 CC Leiden, the Netherlands., Benne N; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Room EE1.17, 2333 CC Leiden, the Netherlands., van der Heijden T; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Room EE1.17, 2333 CC Leiden, the Netherlands., van Puijvelde GH; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Room EE1.17, 2333 CC Leiden, the Netherlands., Kröner MJ; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Room EE1.17, 2333 CC Leiden, the Netherlands., Schaftenaar FH; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Room EE1.17, 2333 CC Leiden, the Netherlands., Foks AC; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Room EE1.17, 2333 CC Leiden, the Netherlands., Wezel A; HMC Westeinde, The Hague, the Netherlands., Smeets H; HMC Westeinde, The Hague, the Netherlands., Yagita H; Department of Immunology, Juntendo University School of Medicine, Hongo, Bunkyo-ku, Tokyo, Japan., Bot I; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Room EE1.17, 2333 CC Leiden, the Netherlands., Jiskoot W; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Room EE1.17, 2333 CC Leiden, the Netherlands., Kuiper J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Room EE1.17, 2333 CC Leiden, the Netherlands., Slütter B; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Room EE1.17, 2333 CC Leiden, the Netherlands.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2019 Mar 15; Vol. 115 (4), pp. 729-738.

Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice.

Autor: Kritikou E; Division of Biopharmaceutics, LACDR, Leiden University, The Netherlands., van Puijvelde GH; Division of Biopharmaceutics, LACDR, Leiden University, The Netherlands., van der Heijden T; Division of Biopharmaceutics, LACDR, Leiden University, The Netherlands., van Santbrink PJ; Division of Biopharmaceutics, LACDR, Leiden University, The Netherlands., Swart M; Division of Biopharmaceutics, LACDR, Leiden University, The Netherlands., Schaftenaar FH; Division of Biopharmaceutics, LACDR, Leiden University, The Netherlands., Kröner MJ; Division of Biopharmaceutics, LACDR, Leiden University, The Netherlands., Kuiper J; Division of Biopharmaceutics, LACDR, Leiden University, The Netherlands., Bot I; Division of Biopharmaceutics, LACDR, Leiden University, The Netherlands.

Publikováno v: Scientific reports [Sci Rep] 2016 Nov 24; Vol. 6, pp. 37585. Date of Electronic Publication: 2016 Nov 24.

Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages.

Autor: Frodermann V; Division of Biopharmaceutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., van Duijn J; Division of Biopharmaceutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., van Puijvelde GH; Division of Biopharmaceutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., van Santbrink PJ; Division of Biopharmaceutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Lagraauw HM; Division of Biopharmaceutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., de Vries MR; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Quax PH; Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Bot I; Division of Biopharmaceutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Foks AC; Division of Biopharmaceutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., de Jager SC; Division of Biopharmaceutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Laboratory for Experimental Cardiology and Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands., Kuiper J; Division of Biopharmaceutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.

Publikováno v: Journal of internal medicine [J Intern Med] 2016 Jun; Vol. 279 (6), pp. 592-605. Date of Electronic Publication: 2016 Feb 23.

A multivalent ligand for the mannose-6-phosphate receptor for endolysosomal targeting of an activity-based probe.

Autor: Hoogendoorn S; Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA, Leiden (The Netherlands)., van Puijvelde GH, Kuiper J, van der Marel GA, Overkleeft HS

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2014 Oct 06; Vol. 53 (41), pp. 10975-8. Date of Electronic Publication: 2014 Aug 27.