LRH-1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype.

Autor: Cobo-Vuilleumier N; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain.; Nadia Cobo-Vuilleumier and Petra I Lorenzo, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain., Rodríguez-Fernandez S; Immunology Department, Germans Trias i Pujol Research Institute, Autonomous University of Barcelona, Badalona, Spain., López-Noriega L; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain., Lorenzo PI; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain.; Nadia Cobo-Vuilleumier and Petra I Lorenzo, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain., Franco JM; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain., Lachaud CC; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain., Vazquez EM; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain.; ULB Center for Diabetes Research, Medical Faculty, Université Libre de Bruxelles (ULB), Brussels, Belgium., Legido RA; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain.; Nadia Cobo-Vuilleumier and Petra I Lorenzo, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain., Dorronsoro A; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain., López-Férnandez-Sobrino R; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain., Fernández-Santos B; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain., Serrano CE; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain., Salas-Lloret D; Cell and Chemical Biology, Leiden University Medical Centre, Leiden, The Netherlands., van Overbeek N; Cell and Chemical Biology, Leiden University Medical Centre, Leiden, The Netherlands., Ramos-Rodriguez M; Pompeu Fabra University, Barcelona, Spain., Mateo-Rodríguez C; Department of Endocrinology and Nutrition, University Hospital Virgen Macarena, Sevilla, Spain., Hidalgo L; Department of Endocrinology and Nutrition, University Hospital Virgen Macarena, Sevilla, Spain., Marin-Canas S; ULB Center for Diabetes Research, Medical Faculty, Université Libre de Bruxelles (ULB), Brussels, Belgium., Nano R; Diabetes Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy., Arroba AI; Department of Endocrinology and Nutrition, University Hospital Puerta del Mar, Institute of Research and Innovation in Biomedical Sciences of Cádiz (INiBICA). University of Cádiz (UCA), Cádiz, Spain., Caro AC; Department of Endocrinology and Nutrition, University Hospital Puerta del Mar, Institute of Research and Innovation in Biomedical Sciences of Cádiz (INiBICA). University of Cádiz (UCA), Cádiz, Spain., Vertegaal AC; Cell and Chemical Biology, Leiden University Medical Centre, Leiden, The Netherlands., Montalvo AM; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain., Martín F; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain.; Nadia Cobo-Vuilleumier and Petra I Lorenzo, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain., Aguilar-Diosdado M; Department of Endocrinology and Nutrition, University Hospital Puerta del Mar, Institute of Research and Innovation in Biomedical Sciences of Cádiz (INiBICA). University of Cádiz (UCA), Cádiz, Spain., Piemonti L; Diabetes Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy., Pasquali L; Pompeu Fabra University, Barcelona, Spain., Prieto RG; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain.; Department of Cell Biology, Faculty of Biology, University of Sevilla, Sevilla, Spain., Sánchez MIG; Biobank of the Andalusian Public Health System, Node Hospital Virgen Macarena, Sevilla, Spain., Eizirik DL; ULB Center for Diabetes Research, Medical Faculty, Université Libre de Bruxelles (ULB), Brussels, Belgium., Martínez-Brocca MA; Department of Endocrinology and Nutrition, University Hospital Puerta del Mar, Institute of Research and Innovation in Biomedical Sciences of Cádiz (INiBICA). University of Cádiz (UCA), Cádiz, Spain., Vives-Pi M; Immunology Department, Germans Trias i Pujol Research Institute, Autonomous University of Barcelona, Badalona, Spain., Gauthier BR; Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain.; Nadia Cobo-Vuilleumier and Petra I Lorenzo, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain.

Publikováno v: Clinical and translational medicine [Clin Transl Med] 2024 Dec; Vol. 14 (12), pp. e70134.

Protein Quality Control Systems and ER Stress as Key Players in SARS-CoV-2-Induced Neurodegeneration.

Autor: Gavilán, Elena^1,2 (AUTHOR) elenagavilan@gmail.com, Medina-Guzman, Rafael¹ (AUTHOR) bahatyrevich@gmail.com, Bahatyrevich-Kharitonik, Bazhena^1,2 (AUTHOR) ruano@us.es, Ruano, Diego^1,2 (AUTHOR)

Publikováno v: Cells (2073-4409). Jan2024, Vol. 13 Issue 2, p123. 32p.

Quantitative mapping of proteasome interactomes and substrates using ProteasomeID.

Autor: Bartolome, Aleksandar, Heiby, Julia C., Di Fraia, Domenico, Heinze, Ivonne, Knaudt, Hannah, Spaeth, Ellen, Omrani, Omid, Minetti, Alberto, Hofmann, Maleen, Kirkpatrick, Joanna M., Dau, Therese, Ori, Alessandro

Publikováno v: eLife; 9/4/2024, p1-32, 32p

DoUBLing up: ubiquitin and ubiquitin-like proteases in genome stability.

Autor: Foster, Benjamin M., Wang, Zijuan, Schmidt, Christine K.

Publikováno v: Biochemical Journal; Apr2024, Vol. 481 Issue 7, p515-545, 31p

Deubiquitinase PSMD14 promotes tumorigenicity of glioblastoma by deubiquitinating and stabilizing β-catenin.

Autor: Wang Y; Department of Neurosurgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Liu Y; Department of Neurosurgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Ma C; Department of Neurosurgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.; Huaian Hospital of Huaian City, Huaian Cancer Hospital, China., Liu C; Department of Neurosurgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Tang Q; Department of Neurosurgery, Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China., Wang Z; Department of Neurosurgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Lu J; Department of Neurosurgery, Jiangsu Provincial Hospital of Traditional Chinese Medicine, Nanjing, China., Chen Z; Department of Neurosurgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Wang H; Department of Neurosurgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Publikováno v: BioFactors (Oxford, England) [Biofactors] 2024 Nov-Dec; Vol. 50 (6), pp. 1134-1147. Date of Electronic Publication: 2024 May 02.