Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets

Autor: Van Osch, TLJ, Oosterhoff, JJ, Bentlage, AEH, Nouta, J, Koeleman, CAM, Geerdes, DM, Mok, JY, Heidt, S, Mulder, A, Van, Esch WJE, Kapur, R, Porcelijn, L, Vidarsson, G

Approximately 20% of patients receiving multiple platelet transfusions develop platelet alloantibodies, which can be directed against human leukocyte antigens (HLA) and, to a lesser extent, against human platelet antigens (HPA). These antibodies can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::237f479dc5e85270f11e77484e27de9e
https://dspace.library.uu.nl/handle/1874/423183

Complement activation drives antibody-mediated transfusion-related acute lung injury via macrophage trafficking and formation of NETs.

Autor: van der Velden S; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., van Osch TLJ; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Seghier A; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Bentlage AEH; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Mok JY; Sanquin Reagents, Amsterdam, The Netherlands., Geerdes DM; Sanquin Reagents, Amsterdam, The Netherlands., van Esch WJE; Sanquin Reagents, Amsterdam, The Netherlands., Pouw RB; Department of Immunopathology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, The Netherlands., Brouwer MC; Department of Immunopathology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, The Netherlands., Jongerius I; Department of Immunopathology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, The Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands., de Haas M; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Immunohematology Diagnostics, Sanquin Diagnostic Services, Amsterdam, The Netherlands.; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, The Netherlands., Porcelijn L; Department of Immunohematology Diagnostics, Sanquin Diagnostic Services, Amsterdam, The Netherlands., van der Schoot CE; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Vidarsson G; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Kapur R; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Publikováno v: Blood [Blood] 2024 Jan 04; Vol. 143 (1), pp. 79-91.

The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees.

Autor: Van Coillie J; Department of Experimental Immunohematology, Sanquin Research, Amsterdam, the Netherlands; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands., Pongracz T; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands., Rahmöller J; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Medical Center of Schleswig-Holstein, Lübeck, Germany; Department of Anesthesiology and Intensive Care, University of Lübeck and University Medical Center of Schleswig-Holstein, Lübeck, Germany., Chen HJ; Department of Medical Biochemistry, Experimental Vascular Biology, Amsterdam Cardiovascular Sciences, Amsterdam Infection and Immunity, Amsterdam UMC, University of Amsterdam, the Netherlands., Geyer CE; Center for Experimental and Molecular Medicine, Amsterdam Infection & Immunity Institute, Amsterdam, the Netherlands., van Vught LA; Center for Experimental and Molecular Medicine, Amsterdam Infection & Immunity Institute, Amsterdam, the Netherlands; Department of Intensive Care, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Buhre JS; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Medical Center of Schleswig-Holstein, Lübeck, Germany., Šuštić T; Department of Experimental Immunohematology, Sanquin Research, Amsterdam, the Netherlands; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands., van Osch TLJ; Department of Experimental Immunohematology, Sanquin Research, Amsterdam, the Netherlands; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands., Steenhuis M; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands; Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands., Hoepel W; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Rheumatology and Clinical Immunology, Amsterdam UMC, Amsterdam Rheumatology and Immunology Center, Amsterdam, the Netherlands., Wang W; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands., Lixenfeld AS; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Medical Center of Schleswig-Holstein, Lübeck, Germany., Nouta J; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands., Keijzer S; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands; Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands., Linty F; Department of Experimental Immunohematology, Sanquin Research, Amsterdam, the Netherlands; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands., Visser R; Department of Experimental Immunohematology, Sanquin Research, Amsterdam, the Netherlands; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands., Larsen MD; Department of Experimental Immunohematology, Sanquin Research, Amsterdam, the Netherlands; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands., Martin EL; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Medical Center of Schleswig-Holstein, Lübeck, Germany., Künsting I; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Medical Center of Schleswig-Holstein, Lübeck, Germany., Lehrian S; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Medical Center of Schleswig-Holstein, Lübeck, Germany., von Kopylow V; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Medical Center of Schleswig-Holstein, Lübeck, Germany., Kern C; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Medical Center of Schleswig-Holstein, Lübeck, Germany., Lunding HB; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Medical Center of Schleswig-Holstein, Lübeck, Germany., de Winther M; Department of Medical Biochemistry, Experimental Vascular Biology, Amsterdam Cardiovascular Sciences, Amsterdam Infection and Immunity, Amsterdam UMC, University of Amsterdam, the Netherlands., van Mourik N; Center for Experimental and Molecular Medicine, Amsterdam Infection & Immunity Institute, Amsterdam, the Netherlands; Department of Intensive Care, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Rispens T; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands; Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands., Graf T; Medical Department 2, University Heart Center of Schleswig-Holstein, Lübeck, Germany., Slim MA; Center for Experimental and Molecular Medicine, Amsterdam Infection & Immunity Institute, Amsterdam, the Netherlands; Department of Intensive Care, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Minnaar RP; Amsterdam UMC Biobank, Amsterdam UMC, Amsterdam, the Netherlands., Bomers MK; Department of Internal Medicine, Amsterdam Infection and Immunity Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands., Sikkens JJ; Department of Internal Medicine, Amsterdam Infection and Immunity Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands., Vlaar APJ; Department of Intensive Care, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., van der Schoot CE; Department of Experimental Immunohematology, Sanquin Research, Amsterdam, the Netherlands; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands., den Dunnen J; Center for Experimental and Molecular Medicine, Amsterdam Infection & Immunity Institute, Amsterdam, the Netherlands., Wuhrer M; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: M.wuhrer@lumc.nl., Ehlers M; Laboratories of Immunology and Antibody Glycan Analysis, Institute of Nutritional Medicine, University of Lübeck and University Medical Center of Schleswig-Holstein, Lübeck, Germany; Airway Research Center North, University of Lübeck, German Center for Lung Research (DZL), Lübeck, Germany. Electronic address: Marc.ehlers@uksh.de., Vidarsson G; Department of Experimental Immunohematology, Sanquin Research, Amsterdam, the Netherlands; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands. Electronic address: G.Vidarsson@sanquin.nl.

Publikováno v: EBioMedicine [EBioMedicine] 2023 Jan; Vol. 87, pp. 104408. Date of Electronic Publication: 2022 Dec 16.

Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets.

Autor: Van Osch TLJ; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam., Oosterhoff JJ; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam., Bentlage AEH; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam., Nouta J; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden., Koeleman CAM; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden., Geerdes DM; Sanquin Reagents, Amsterdam., Mok JY; Sanquin Reagents, Amsterdam., Heidt S; Department of Immunology, Leiden University Medical Center, Leiden., Mulder A; Department of Immunology, Leiden University Medical Center, Leiden., Van Esch WJE; Sanquin Reagents, Amsterdam., Kapur R; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam., Porcelijn L; Department of Immunohaematology Diagnostics, Sanquin Diagnostic Services, Amsterdam., Van der Schoot CE; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam., De Haas M; Department of Immunology, Leiden University Medical Center, Leiden, the Netherlands; Department of Immunohaematology Diagnostics, Sanquin Diagnostic Services, Amsterdam., Wuhrer M; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden., Voorberg J; Departement of Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam., Vidarsson G; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam. G.Vidarsson@sanquin.nl.

Publikováno v: Haematologica [Haematologica] 2022 Oct 01; Vol. 107 (10), pp. 2432-2444. Date of Electronic Publication: 2022 Oct 01.

Biological and structural characterization of murine TRALI antibody reveals increased Fc-mediated complement activation.

Autor: Zeeuw van der Laan EAN; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., van der Velden S; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Bentlage AEH; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Larsen MD; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., van Osch TLJ; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Mok JY; Sanquin Reagents, Amsterdam, The Netherlands., Brasser G; Sanquin Reagents, Amsterdam, The Netherlands., Geerdes DM; Sanquin Reagents, Amsterdam, The Netherlands., Koeleman CAM; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., Nouta J; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., Semple JW; Division of Hematology and Transfusion Medicine, Lund University, Lund, Sweden; and., Porcelijn L; Department of Immunohematology Diagnostics, Sanquin Diagnostic Services, Amsterdam, The Netherlands., van Esch WJE; Sanquin Reagents, Amsterdam, The Netherlands., Wuhrer M; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., van der Schoot CE; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Vidarsson G; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Kapur R; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Publikováno v: Blood advances [Blood Adv] 2020 Aug 25; Vol. 4 (16), pp. 3875-3885.