Absence of Functional Autoantibodies Targeting Angiotensin II Type 1 Receptor (AT 1 R) and Endothelin-1 Type A Receptor (ET A R) in Circulation and Purified IgG from Patients with Systemic Sclerosis.

Autor: van Oostveen WM; Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Hoekstra EM; Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Levarht EWN; Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Kotliar IB; Laboratory of Chemical Biology and Signal Transduction, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA.; Tri-Institutional PhD Program in Chemical Biology, New York, NY, 10065, USA., Sakmar TP; Laboratory of Chemical Biology and Signal Transduction, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA., Toes REM; Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., de Vries-Bouwstra JK; Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Heitman LH; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, Wassenaarseweg 76, 2333 AL, Leiden, The Netherlands.; Oncode Institute, Leiden, The Netherlands., Fehres CM; Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

Publikováno v: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2024 Dec 25. Date of Electronic Publication: 2024 Dec 25.

Label-free detection of prostaglandin transporter (SLCO2A1) function and inhibition: insights by wound healing and TRACT assays.

Autor: Mocking TAM; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, Netherlands., van Oostveen WM; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, Netherlands.; Department of Rheumatology, Leiden University Medical Center, Leiden University, Leiden, Netherlands.; Immunology and Respiratory Diseases, Boehringer-Ingelheim, Ridgefield, CT, United States.; Oncode Institute, Leiden, Netherlands., van Veldhoven JPD; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, Netherlands.; Department of Rheumatology, Leiden University Medical Center, Leiden University, Leiden, Netherlands.; Immunology and Respiratory Diseases, Boehringer-Ingelheim, Ridgefield, CT, United States.; Oncode Institute, Leiden, Netherlands., Minnee H; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, Netherlands., Fehres CM; Department of Rheumatology, Leiden University Medical Center, Leiden University, Leiden, Netherlands., Whitehurst CE; Immunology and Respiratory Diseases, Boehringer-Ingelheim, Ridgefield, CT, United States., IJzerman AP; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, Netherlands., Heitman LH; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, Netherlands.; Oncode Institute, Leiden, Netherlands.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2024 May 09; Vol. 15, pp. 1372109. Date of Electronic Publication: 2024 May 09 (Print Publication: 2024).

Imaging Techniques in Alzheimer's Disease: A Review of Applications in Early Diagnosis and Longitudinal Monitoring.

Autor: van Oostveen WM; Faculty of Science, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands., de Lange ECM; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre of Drug Research, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Feb 20; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 20.