Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patients.

Autor: Genshaft AS; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Massachusetts, USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Subudhi S; Liver Center, Division of Gastroenterology and Liver Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Keo A; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.; Cancer Computational Biology Center, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, the Netherlands., Sanchez Vasquez JD; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario, Canada., Conceição-Neto N; Infectious Diseases Biomarkers, Janssen Research and Development, Beerse, Belgium., Mahamed D; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada., Boeijen LL; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Alatrakchi N; Liver Center, Division of Gastroenterology and Liver Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Oetheimer C; Liver Center, Division of Gastroenterology and Liver Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Vilme M; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Massachusetts, USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Drake R; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Massachusetts, USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Fleming I; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Massachusetts, USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Tran N; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Massachusetts, USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Tzouanas C; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Massachusetts, USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Joseph-Chazan J; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Massachusetts, USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Immunology, Harvard Medical School, Boston, Massachusetts, USA., Arreola Villanueva M; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Massachusetts, USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., van de Werken HJG; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.; Cancer Computational Biology Center, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, the Netherlands.; Department of Urology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, the Netherlands.; Department of Immunology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, the Netherlands., van Oord GW; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Groothuismink ZMA; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Beudeker BJ; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Osmani Z; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Nkongolo S; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada., Mehrotra A; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada., Spittaels K; Infectious Diseases Biomarkers, Janssen Research and Development, Beerse, Belgium., Feld J; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada., Chung RT; Liver Center, Division of Gastroenterology and Liver Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., de Knegt RJ; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Janssen HLA; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada., Aerssens J; Infectious Diseases Biomarkers, Janssen Research and Development, Beerse, Belgium., Bollekens J; Infectious Diseases Biomarkers, Janssen Research and Development, Beerse, Belgium., Hacohen N; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Immunology, Harvard Medical School, Boston, Massachusetts, USA., Lauer GM; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, Massachusetts, USA., Boonstra A; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Shalek AK; Institute for Medical Engineering and Science (IMES), Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Massachusetts, USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Gehring AJ; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2023 Nov 01; Vol. 78 (5), pp. 1525-1541. Date of Electronic Publication: 2023 May 10.

Treatment induced clearance of hepatitis E viruses by interferon-lambda in liver-humanized mice.

Autor: Sari G; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands., Mulders CE; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands., Zhu J; Center for Vaccines and Immunity, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA., van Oord GW; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands., Feng Z; Center for Vaccines and Immunity, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, USA., Kreeft-Voermans JJC; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands., Boonstra A; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands., Vanwolleghem T; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Laboratory of Experimental Medicine and Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.; Department of Gastroenterology and Hepatology, Antwerp University Hospital, Antwerp, Belgium.

Publikováno v: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2021 Dec; Vol. 41 (12), pp. 2866-2873. Date of Electronic Publication: 2021 Aug 29.

Hepatitis B core-related antigen monitoring during peginterferon alfa treatment for HBeAg-negative chronic hepatitis B.

Autor: van Campenhout MJH; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Rijckborst V; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Brouwer WP; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., van Oord GW; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Ferenci P; Department of Internal Medicine, Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria., Tabak F; Cerrahpasa Medical Faculty, Istanbul, Turkey., Akdogan M; Department of Gastroenterology, Yuksek Ihtisas Hospital, Ankara, Turkey., Pinarbasi B; Division of Gastroenterohepatology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey., Simon K; Division of Infectious Diseases and Hepatology, Wroclaw Medical University, Wroclaw, Poland., de Knegt RJ; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Boonstra A; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Janssen HLA; Toronto Center for Liver Disease, Toronto Western and General Hospital, University Health Network, Toronto, Ontario, Canada., Hansen BE; Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.; Toronto Center for Liver Disease, Toronto Western and General Hospital, University Health Network, Toronto, Ontario, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

Publikováno v: Journal of viral hepatitis [J Viral Hepat] 2019 Oct; Vol. 26 (10), pp. 1156-1163. Date of Electronic Publication: 2019 Aug 04.

Diagnostic and analytical performance of the hepatitis B core related antigen immunoassay in hepatitis B patients.

Autor: van Halewijn GJ; Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, the Netherlands; Department of Viroscience, Erasmus MC, University Medical Center Rotterdam, the Netherlands., Geurtsvankessel CH; Department of Viroscience, Erasmus MC, University Medical Center Rotterdam, the Netherlands., Klaasse J; Department of Viroscience, Erasmus MC, University Medical Center Rotterdam, the Netherlands., van Oord GW; Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, the Netherlands., de Knegt RJ; Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, the Netherlands., van Campenhout MJ; Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, the Netherlands., Boonstra A; Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, the Netherlands., van der Eijk AA; Department of Viroscience, Erasmus MC, University Medical Center Rotterdam, the Netherlands. Electronic address: a.vandereijk@erasmusmc.nl.

Publikováno v: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology [J Clin Virol] 2019 May; Vol. 114, pp. 1-5. Date of Electronic Publication: 2019 Mar 04.

Mucosal-associated invariant T-cell frequency and function in blood and liver of HCV mono- and HCV/HIV co-infected patients with advanced fibrosis.

Autor: Beudeker BJB; Department of Gastroenterology and Hepatology, Infectious Diseases Section, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Internal Medicine, Infectious Diseases Section, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., van Oord GW; Department of Gastroenterology and Hepatology, Infectious Diseases Section, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Arends JE; Department of Internal Medicine and Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands., Schulze Zur Wiesch J; Department of Medicine, University Medical Center, Hamburg-Eppendorf, Germany., van der Heide MS; Department of Gastroenterology and Hepatology, Infectious Diseases Section, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., de Knegt RJ; Department of Gastroenterology and Hepatology, Infectious Diseases Section, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Verbon A; Department of Internal Medicine, Infectious Diseases Section, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Boonstra A; Department of Gastroenterology and Hepatology, Infectious Diseases Section, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Claassen MAA; Department of Gastroenterology and Hepatology, Infectious Diseases Section, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Internal Medicine, Infectious Diseases Section, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Publikováno v: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2018 Mar; Vol. 38 (3), pp. 458-468. Date of Electronic Publication: 2017 Sep 16.