Is distance from equilibrium a good indicator for a reaction's flux control?

Autor: van Niekerk DD; Department of Biochemistry, Stellenbosch University, South Africa., Rust E; Department of Biochemistry, Stellenbosch University, South Africa., Bruggeman F; Molecular Cell Biology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Westerhoff HV; Molecular Cell Biology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands; Swammerdam Institute for Life Sciences, University of Amsterdam, Sciencepark 904, 1098 XH Amsterdam, The Netherlands; School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK; Stellenbosch Institute of Advanced Studies (STIAS), Wallenberg Research Centre at Stellenbosch University, Stellenbosch 7600, South Africa., Snoep JL; Department of Biochemistry, Stellenbosch University, South Africa; Molecular Cell Biology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. Electronic address: jls@sun.ac.za.

Publikováno v: Bio Systems [Biosystems] 2023 Oct; Vol. 232, pp. 104988. Date of Electronic Publication: 2023 Aug 02.

Inhibitor titrations reveal low control of glyceraldehyde 3-phosphate dehydrogenase and high control of hexokinase on glycolytic flux in an aggressive triple-negative breast cancer cell line.

Autor: Kouril T; Department of Biochemistry, Stellenbosch University, South Africa., October C; Department of Biochemistry, Stellenbosch University, South Africa., Hollocks S; Department of Biochemistry, Stellenbosch University, South Africa., Odendaal C; Department of Biochemistry, Stellenbosch University, South Africa., van Niekerk DD; Department of Biochemistry, Stellenbosch University, South Africa., Snoep JL; Department of Biochemistry, Stellenbosch University, South Africa; Molecular Cell Biology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. Electronic address: jls@sun.ac.za.

Publikováno v: Bio Systems [Biosystems] 2023 Sep; Vol. 231, pp. 104969. Date of Electronic Publication: 2023 Jul 07.

Computational modelling of the Δ4 and Δ5 adrenal steroidogenic pathways provides insight into hypocortisolism.

Autor: Louw C; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa., van Schalkwyk EJ; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa; LCMS Central Analytical Facility, Stellenbosch University, Stellenbosch, South Africa., Conradie R; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa., Louw R; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa., Engelbrecht Y; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa., Storbeck KH; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa., Swart AC; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa; Department of Chemistry and Polymer Science, Stellenbosch University, Stellenbosch, South Africa., van Niekerk DD; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa., Snoep JL; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa; Department of Molecular Cell Physiology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; MIB, University of Manchester, Manchester, UK. Electronic address: jls@sun.ac.za., Swart P; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa. Electronic address: pswart@sun.ac.za.

Publikováno v: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2021 Apr 15; Vol. 526, pp. 111194. Date of Electronic Publication: 2021 Feb 13.

Studying Glycolytic Oscillations in Individual Yeast Cells by Combining Fluorescence Microscopy with Microfluidics and Optical Tweezers.

Autor: Gustavsson AK; Department of Physics, University of Gothenburg, Gothenburg, Sweden.; Current addresses: Department of Chemistry, Stanford University, Stanford, California and Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden., Banaeiyan AA; Department of Physics, University of Gothenburg, Gothenburg, Sweden., van Niekerk DD; Department of Biochemistry, Stellenbosch University, Matieland, South Africa., Snoep JL; Department of Biochemistry, Stellenbosch University, Matieland, South Africa.; Molecular Cell Physiology, Vrije Universiteit, Amsterdam, The Netherlands.; Manchester Centre for Integrative Systems Biology, Manchester Interdisciplinary Biocentre, The University of Manchester, United Kingdom., Adiels CB; Department of Physics, University of Gothenburg, Gothenburg, Sweden., Goksör M; Department of Physics, University of Gothenburg, Gothenburg, Sweden.

Publikováno v: Current protocols in cell biology [Curr Protoc Cell Biol] 2019 Mar; Vol. 82 (1), pp. e70. Date of Electronic Publication: 2018 Oct 17.

The JWS online simulation database.

Autor: Peters M; Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany., Eicher JJ; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa., van Niekerk DD; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa., Waltemath D; Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany., Snoep JL; Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa.; MIB, CEAS, University of Manchester, UK.; Molecular Cell Physiology, VU University, Amsterdam, The Netherlands.

Publikováno v: Bioinformatics (Oxford, England) [Bioinformatics] 2017 May 15; Vol. 33 (10), pp. 1589-1590.