Sugammadex hypersensitivity and underlying mechanisms: a randomised study of healthy non-anaesthetised volunteers.

Autor: de Kam PJ; Merck & Co., Inc., Kenilworth, NJ, USA., Nolte H; Merck & Co., Inc., Kenilworth, NJ, USA., Good S; Merck & Co., Inc., Kenilworth, NJ, USA., Yunan M; Merck & Co., Inc., Kenilworth, NJ, USA., Williams-Herman DE; Merck & Co., Inc., Kenilworth, NJ, USA., Burggraaf J; Centre for Human Drug Research and Leiden University, Leiden, The Netherlands., Kluft C; Good Biomarker Sciences, Leiden, The Netherlands., Adkinson NF; Johns Hopkins Asthma and Allergy Center, Baltimore, MD, USA., Cullen C; Merck & Co., Inc., Kenilworth, NJ, USA., Skov PS; RefLab ApS, Copenhagen, Denmark., Levy JH; Duke University School of Medicine, Cardiothoracic Anesthesiology and Critical Care, Durham, NC, USA., van den Dobbelsteen DJ; MSD, Oss, The Netherlands., van Heumen ELGM; MSD, Oss, The Netherlands., van Meel FCM; MSD, Oss, The Netherlands., Glassner D; Merck & Co., Inc., Kenilworth, NJ, USA., Woo T; Merck & Co., Inc., Kenilworth, NJ, USA., Min KC; Merck & Co., Inc., Kenilworth, NJ, USA. Electronic address: kwan-hong.chris.min@merck.com., Peeters PAM; MSD, Oss, The Netherlands.

Publikováno v: British journal of anaesthesia [Br J Anaesth] 2018 Oct; Vol. 121 (4), pp. 758-767. Date of Electronic Publication: 2018 Jul 13.