Does serous tubal intraepithelial carcinoma (STIC) metastasize? The clonal relationship between STIC and subsequent high-grade serous carcinoma in BRCA1/2 mutation carriers several years after risk-reducing salpingo-oophorectomy

Autor: van den Berg, C.B., Dasgupta, S., Ewing-Graham, P.C., Bart, J., Bulten, J., Gaarenstroom, K.N., de Hullu, J.A., Mom, C.H., Mourits, M.J.E., Steenbeek, M.P., van Marion, R., van Beekhuizen, H.J.

Publikováno v: In Gynecologic Oncology August 2024 187:113-119

Clinical Utility of Circulating Tumor DNA in Patients With Advanced KRAS ^G12C -Mutated NSCLC Treated With Sotorasib.

Autor: Ernst SM; Department of Respiratory Medicine, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., van Marion R; Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands., Atmodimedjo PN; Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands., de Jonge E; Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands., Mathijssen RHJ; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Paats MS; Department of Respiratory Medicine, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., de Bruijn P; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Koolen SL; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands; Department of Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands., von der Thüsen JH; Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands., Aerts JGJV; Department of Respiratory Medicine, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., van Schaik RHN; Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands., Dubbink HJ; Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands., Dingemans AC; Department of Respiratory Medicine, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands. Electronic address: a.dingemans@erasmusmc.nl.

Publikováno v: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2024 Jul; Vol. 19 (7), pp. 995-1006. Date of Electronic Publication: 2024 Apr 12.

Efficacy and Tolerability of Osimertinib and Sotorasib Combination Treatment for Osimertinib Resistance Caused by KRAS G12C Mutation: A Report of Two Cases.

Autor: Ernst SM; Department of Respiratory Medicine, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, the Netherlands., Uzun S; Department of Respiratory Medicine, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, the Netherlands.; Department of Respiratory Medicine, Haaglanden Medisch Centrum, Den Haag, the Netherlands., Paats MS; Department of Respiratory Medicine, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, the Netherlands., van Marion R; Department of Pathology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Atmodimedjo PN; Department of Pathology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., de Jonge E; Department of Clinical Chemistry, Erasmus MC University Medical Center, Rotterdam, the Netherlands., van Schaik RHN; Department of Clinical Chemistry, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Aerts JGJV; Department of Respiratory Medicine, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, the Netherlands., von der Thüsen JH; Department of Pathology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Dubbink HJ; Department of Pathology, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Dingemans AC; Department of Respiratory Medicine, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, the Netherlands.

Publikováno v: JCO precision oncology [JCO Precis Oncol] 2023 Sep; Vol. 7, pp. e2300451.

Machine learning-based somatic variant calling in cell-free DNA of metastatic breast cancer patients using large NGS panels.

Autor: Jongbloed EM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., Jansen MPHM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., de Weerd V; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., Helmijr JA; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., Beaufort CM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., Reinders MJT; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands., van Marion R; Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., van IJcken WFJ; Erasmus Center for Biomics, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands., Sonke GS; Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Konings IR; Department of Medical Oncology, Amsterdam UMC, location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Jager A; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., Martens JWM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., Wilting SM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands., Makrodimitris S; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands. s.makrodimitris@erasmusmc.nl.; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands. s.makrodimitris@erasmusmc.nl.

Publikováno v: Scientific reports [Sci Rep] 2023 Jun 27; Vol. 13 (1), pp. 10424. Date of Electronic Publication: 2023 Jun 27.

Chromosomal mosaicism in human blastocysts: a cytogenetic comparison of trophectoderm and inner cell mass after next-generation sequencing.

Autor: Chavli E; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands. Electronic address: e.chavli@erasmusmc.nl., van den Born M; Department of Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., Eleveld C; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., Boter M; Department of Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., van Marion R; Department of Pathology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., Hoefsloot L; Department of Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., Laven J; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., Baart E; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands; Department of Developmental Biology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., Van Opstal D; Department of Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

Publikováno v: Reproductive biomedicine online [Reprod Biomed Online] 2022 Nov; Vol. 45 (5), pp. 867-877. Date of Electronic Publication: 2022 Jun 13.