Výsledky vyhledávání - "van Luyn, MJA"

The Use of Fibrous, Supramolecular Membranes and Human Tubular Cells for Renal Epithelial Tissue Engineering: Towards a Suitable Membrane for a Bioartificial Kidney

Autor: Dankers, PYW, Boomker, JM, Huizinga-van de Vlag, A, Smedts, Frank, Harmsen, MC, van Luyn, MJA

Publikováno v: Macromolecular Bioscience, 10(11), 1345-1354. Wiley-VCH

A bioartificial kidney, which is composed of a membrane cartridge with renal epithelial cells, can substitute important kidney functions in patients with renal failure. A particular challenge is the maintenance of monolayer integrity and specialized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::194273344fabfc36377e765e1756f728
https://pure.eur.nl/en/publications/0bdeda4a-12b1-48c8-b0d0-82222e8574f9

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Cardiac tissue engineering: characteristics of in unison contracting two- and three-dimensional neonatal rat ventricle cell (co)-cultures

Autor: van Luyn, MJA, Tio, RA, van Seijen, XJGY, Plantinga, JA, de Leij, LFMH, DeJongste, MJL, van Wachem, PB

Publikováno v: Biomaterials, 23(24):PII S0142-9612(02)00230-2, 4793-4801. ELSEVIER SCI LTD

Patients with heart failure have, in spite of improved palliative therapies, bad prognosis. Cardiac tissue engineering by use of a temporary bioscaffold and cardiomyocytes may help to find answers for future treatments in heart failure. For that purp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::eedcb02a14b98d3e83f8b9283a20df14
https://research.rug.nl/en/publications/d58281db-7065-4b89-b4e5-983f4905a381

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(Electron) microscopic observations on tissue integration of collagen-immobilized polyurethane

Autor: van Wachem, PB, Hendricks, M, Blaauw, EH, Dijk, F, Verhoeven, MLPM, Cahalan, PT, van Luyn, MJA

Publikováno v: Biomaterials, 23(6), 1401-1409. ELSEVIER SCI LTD

The foreign body reactions to collagen-immobilized polyurethane (PU-CI) films during subcutaneous implantation in rats were characterized. The underlying concept is that collagen-immobilization will improve the tissue integration. Since the method of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::53ca623e90eea9770f01d4c206b51853
https://research.rug.nl/en/publications/f382fab6-28be-4362-9d15-b40619cf6b16

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Selective intracellular delivery of dexamethasone into activated endothelial cells using an E-selectin-directed immunoconjugate

Autor: Kok, RJ, Asgeirsdottir, SA, Melgert, BN, Moolenaar, TJM, Koning, GA, van Luyn, MJA, Meijer, DKF, Molema, G

Publikováno v: Journal of Immunology, 168(2), 883-889. AMER ASSOC IMMUNOLOGISTS

In chronic inflammatory diseases, the endothelium is an attractive target for pharmacological intervention because it plays an important role in leukocyte recruitment. Hence, inhibition of endothelial cell activation and consequent leukocyte infiltra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::01dff949de8facc12327f511dd567dec
https://research.rug.nl/en/publications/15ee9478-4cfe-4756-bbb7-0d7c75b63177

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In vivo biocompatibility of carbodiimide-crosslinked collagen matrices: Effects of crosslink density, heparin immobilization, and bFGF loading

Autor: van Wachem, PB, Plantinga, JA, Wissink, MJB, Poot, AA, Engbers, GHM, Beugeling, T, van Aken, WG, Feijen, J, van Luyn, MJA

Publikováno v: Journal of Biomedical Materials Research, 55(3), 368-378. Wiley

Collagen matrices, crosslinked using N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide (E) and N-hydroxvsuccinimide (N), were previously developed as a substrate for endothelial cell seeding of small-diameter vascular grafts. In the present study, the b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::ddfb94de02c7079dc3af3d579fbab92a
https://research.rug.nl/en/publications/802752ef-c298-41b8-a702-930c98a56c43

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The foreign body reaction to a biodegradable biomaterial differs between rats and mice

Autor: Khouw, IMSL, van Wachem, PB, Molema, G, Plantinga, JA, de Leij, LFMH, van Luyn, MJA

Publikováno v: Journal of Biomedical Materials Research, 52(3), 439-446. Wiley

Before a biomaterial can be applied in the clinic, biocompatibility must be tested in in vivo models, by monitoring the foreign body reaction. In this study, we compared the foreign body reaction (EBR) to the biodegradable biomaterial hexamethylenedi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::b051f973acfc59359c8e6cfbdd098d39
https://research.rug.nl/en/publications/976c810f-ecfa-4916-9c6b-5d79ad84a07e

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In vitro and in vivo evaluation of gelatin-chondroitin sulphate hydrogels for controlled release of antibacterial proteins

Autor: Kuijpers, AJ, van Wachem, PB, van Luyn, MJA, Brouwer, LA, Engbers, GHM, Krijgsveld, J, Zaat, SAJ, Feijin, J

Publikováno v: Biomaterials, 21(17), 1763-1772. ELSEVIER SCI LTD

Chemically cross-linked gelatin-chondroitin sulphate (ChS) hydrogels, impregnated in Dacron, were evaluated as drug delivery systems for antibacterial proteins. The gelatin-chondroitin sulphate gels, plain or impregnated in Dacron, were cross-linked

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::d7b05b99d573af0cbcd06b8c33a4e80b
https://research.rug.nl/en/publications/f9b18017-1a2e-473d-9221-d6721e69cfe2

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Endothelial cell seeding on crosslinked collagen: Effects of crosslinking on endothelial cell proliferation and functional parameters

Autor: Wissink, MJB, van Luyn, MJA, Dijk, F, Poot, AA, Engbers, GHM, Beugeling, T, van Aken, WG, Feijen, J

Publikováno v: Thrombosis and Haemostasis, 84(2), 325-+. GEORG THIEME VERLAG KG

Endothelial cell seeding, a promising method to improve the performance of small-diameter vascular grafts, requires a suitable substrate, such as crosslinked collagen. Commonly used crosslinking agents such as glutaraldehyde and formaldehyde cause, h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::45ab2b512c069c3f4c76df655f4b6e0c
https://research.rug.nl/en/publications/1a1bda99-d917-401b-b4cd-0ffbbc6e1b55

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In vivo and in vitro release of lysozyme from cross-linked gelatin hydrogels: a model system for the delivery of antibacterial proteins from prosthetic heart valves

Autor: Kuijpers, AJ, van Wachem, PB, van Luyn, MJA, Engbers, GHM, Krijgsveld, J, Zaat, SAJ, Feijen, J

Publikováno v: Journal of Controlled Release, 67(2-3), 323-336. Elsevier Bedrijfsinformatie b.v.

Prosthetic valve endocarditis may be reduced by the local delivery of antibacterial proteins from the Dacron sewing ring of a prosthetic heart valve. Dacron discs were treated with a carbon dioxide gas plasma to improve the hydrophilicity and thereby

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::e7ab2641b0ce23748aad4c7729c298e1
https://research.rug.nl/en/publications/82a9d9e1-be95-4f6e-9a56-b6c405b679a9

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