From recipe to research: introducing undergraduate students to the nature of science using a hybrid practical course centred on drug discovery for neglected diseases.

Autor: Wijtmans M; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands; Division of Innovations in Human Health and Life Sciences, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Edink E; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands; Current address: Department of Life Sciences and Chemistry, Faculty of Agri, Food and Life Sciences, Inholland University of Applied Sciences, De Boelelaan 1109, 1081 HV Amsterdam, The Netherlands., van Linden OP; Division of Innovations in Human Health and Life Sciences, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Zheng Y; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Blaazer AR; Division of Innovations in Human Health and Life Sciences, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., Siderius M; Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands., van Muijlwijk-Koezen JE; Division of Innovations in Human Health and Life Sciences, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands. Electronic address: j.e.van.muijlwijk-koezen@vu.nl.

Publikováno v: Drug discovery today [Drug Discov Today] 2021 Jun; Vol. 26 (6), pp. 1359-1368. Date of Electronic Publication: 2021 Feb 18.

KLIFS: a knowledge-based structural database to navigate kinase-ligand interaction space.

Autor: van Linden OP; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., Kooistra AJ, Leurs R, de Esch IJ, de Graaf C

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2014 Jan 23; Vol. 57 (2), pp. 249-77. Date of Electronic Publication: 2013 Sep 20.

Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase.

Autor: van Linden OP; Leiden/Amsterdam Center for Drug Research (LACDR), Division of Medicinal Chemistry, Faculty of Sciences, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., Farenc C, Zoutman WH, Hameetman L, Wijtmans M, Leurs R, Tensen CP, Siegal G, de Esch IJ

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2012 Jan; Vol. 47 (1), pp. 493-500. Date of Electronic Publication: 2011 Nov 18.