Neoadjuvant FOLFOXIRI prior to chemoradiotherapy for high-risk ("ugly") locally advanced rectal cancer: study protocol of a single-arm, multicentre, open-label, phase II trial (MEND-IT).

Autor: van den Berg K; Department of Medical Oncology, Catharina Hospital, Eindhoven, the Netherlands.; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands., Schaap DP; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands., Voogt ELK; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands., Buffart TE; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Medical Oncology, Amsterdam University Medical Centres, Amsterdam, the Netherlands., Verheul HMW; Department of Medical Oncology, Radboud University Medical Centre, Nijmegen, the Netherlands., de Groot JWB; Department of Medical Oncology, Isala Oncology Centre, Zwolle, the Netherlands., Verhoef C; Department of Surgical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., Melenhorst J; Department of Surgery, Maastricht University Medical Centre, Maastricht, the Netherlands., Roodhart JML; Department of Medical Oncology, University Medical Centre Utrecht, Utrecht, the Netherlands., de Wilt JHW; Department of Surgery, Radboud University Medical Centre, Nijmegen, the Netherlands., van Westreenen HL; Department of Surgery, Isala, Zwolle, the Netherlands., Aalbers AGJ; Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands., van 't Veer M; Department of Research and Education, Catharina Hospital, Eindhoven, the Netherlands., Marijnen CAM; Department of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Department of Radiation Oncology, Leiden University Medical Center, Leiden, the Netherlands., Vincent J; Department of Medical Oncology, Elkerliek Hospital, Helmond, the Netherlands., Simkens LHJ; Department of Medical Oncology, Maxima Medical Centre, Veldhoven, the Netherlands., Peters NAJB; Department of Medical Oncology, St. Jans Hospital, Weert, the Netherlands., Berbée M; Department of Radiation Oncology (MAASTRO), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, the Netherlands., Werter IM; Department of Medical Oncology, Rijnstate Hospital, Arnhem, the Netherlands., Snaebjornsson P; Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Peulen HMU; Department of Radiation Oncology, Catharina Hospital, Eindhoven, the Netherlands., van Lijnschoten IG; Department of Pathology, PAMM Laboratory for Pathology and Medical Microbiology, Eindhoven, the Netherlands., Roef MJ; Department of Nuclear Medicine, Catharina Hospital, Eindhoven, the Netherlands., Nieuwenhuijzen GAP; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands., Bloemen JG; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands., Willems JMWE; Department of Medical Oncology, Anna Hospital, Geldrop, the Netherlands., Creemers GJM; Department of Medical Oncology, Catharina Hospital, Eindhoven, the Netherlands., Nederend J; Department of Radiology, Catharina Hospital, Eindhoven, the Netherlands., Rutten HJT; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.; GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands., Burger JWA; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands. pim.burger@catharinaziekenhuis.nl.

Publikováno v: BMC cancer [BMC Cancer] 2022 Sep 06; Vol. 22 (1), pp. 957. Date of Electronic Publication: 2022 Sep 06.

Lymphovascular invasion quantification could improve risk prediction of lymph node metastases in patients with submucosal (T1b) esophageal adenocarcinoma.

Autor: van de Ven SEM; Department of Gastroenterology and Hepatology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Suzuki L; Department of Pathology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Gotink AW; Department of Gastroenterology and Hepatology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Ten Kate FJC; Department of Pathology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands.; Department of Pathology, Isala Clinics, Zwolle, The Netherlands., Nieboer D; Department of Public Health, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Weusten BLAM; Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, The Netherlands., Brosens LAA; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., van Hillegersberg R; Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands., Alvarez Herrero L; Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, The Netherlands., Seldenrijk CA; Department of Pathology, Pathology DNA, St. Antonius Hospital, Nieuwegein, The Netherlands., Alkhalaf A; Department of Gastroenterology and Hepatology, Isala Clinics, Zwolle, The Netherlands., Moll FCP; Department of Pathology, Isala Clinics, Zwolle, The Netherlands., Curvers W; Department of Gastroenterology and Hepatology, Catharina Hospital, Eindhoven, The Netherlands., van Lijnschoten IG; Department of Pathology, PAMM, Eindhoven, The Netherlands., Tang TJ; Department of Gastroenterology and Hepatology, Ijsselland Hospital, Capelle aan den Ijssel, The Netherlands., van der Valk H; Department of Pathology, Ijselland Hospital, Capelle aan den Ijssel, The Netherlands., Nagengast WB; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands., Kats-Ugurlu G; Department of Pathology, University Medical Center Groningen, Groningen, The Netherlands., Plukker JTM; Department of Surgery, University Medical Center Groningen, Groningen, The Netherlands., Houben MHMG; Department of Gastroenterology and Hepatology, Haga Teaching Hospital, Den Haag, The Netherlands., van der Laan JS; Department of Pathology, Haga Teaching Hospital, Den Haag, The Netherlands., Pouw RE; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam, The Netherlands., Bergman JJGHM; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam, The Netherlands., Meijer SL; Department of Pathology, Amsterdam University Medical Centers, Amsterdam, The Netherlands., van Berge Henegouwen MI; Department of Surgery, Amsterdam University Medical Centers, Amsterdam, The Netherlands., Wijnhoven BPL; Department of Surgery, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., de Jonge PJF; Department of Gastroenterology and Hepatology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Doukas M; Department of Pathology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Bruno MJ; Department of Gastroenterology and Hepatology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Biermann K; Department of Pathology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands., Koch AD; Department of Gastroenterology and Hepatology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands.

Publikováno v: United European gastroenterology journal [United European Gastroenterol J] 2021 Nov; Vol. 9 (9), pp. 1066-1073. Date of Electronic Publication: 2021 Oct 05.