Zobrazeno 1 - 10
of 1 244
pro vyhledávání: '"van Lent, P."'
Autor:
Jonas Van Lent, Robert Prior, Gonzalo Pérez Siles, Anthony N. Cutrupi, Marina L. Kennerson, Tim Vangansewinkel, Esther Wolfs, Bipasha Mukherjee-Clavin, Zachary Nevin, Luke Judge, Bruce Conklin, Henna Tyynismaa, Alex J. Clark, David L. Bennett, Ludo Van Den Bosch, Mario Saporta, Vincent Timmerman
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 6, Pp 1348-1364 (2024)
Abstract Inherited peripheral neuropathies (IPNs) are a group of diseases associated with mutations in various genes with fundamental roles in the development and function of peripheral nerves. Over the past 10 years, significant advances in identify
Externí odkaz:
https://doaj.org/article/ce0749451b9e4264b20443f390aa833e
Autor:
Erin Noel Jordan, Ramin Shirali Hossein Zade, Stephanie Pillay, Paul van Lent, Thomas Abeel, Oliver Kayser
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Yeast metabolism can be engineered to produce xenobiotic compounds, such as cannabinoids, the principal isoprenoids of the plant Cannabis sativa, through heterologous metabolic pathways. However, yeast cell factories continue to have low can
Externí odkaz:
https://doaj.org/article/beedd90f16534aa5822604a1534eb0fa
Autor:
Jonas Van Lent, Arianna Baggiolini
Publikováno v:
Molecular Oncology, Vol 18, Iss 4, Pp 793-796 (2024)
When we think about cancer, the link to development might not immediately spring to mind. Yet, many foundational concepts in cancer biology trace their roots back to developmental processes. Several defining traits of cancer were indeed initially obs
Externí odkaz:
https://doaj.org/article/526e45c78644459fb2887e33ba79f5dc
Autor:
Liza G. G. van Lent, Mirte van der Ham, Maja J. A. de Jonge, Eelke H. Gort, Marjolein van Mil, Jeroen Hasselaar, Carin C. D. van der Rijt, Jelle van Gurp, Julia C. M. van Weert
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Patients with advanced cancer who no longer have standard treatment options available may decide to participate in early phase clinical trials (i.e. experimental treatments with uncertain outcomes). Shared decision-making (SDM) mo
Externí odkaz:
https://doaj.org/article/6f31e3daebe4460897279e0a955a9984
CD64 as novel molecular imaging marker for the characterization of synovitis in rheumatoid arthritis
Autor:
Wessel F. Theeuwes, Irene Di Ceglie, Daphne N. Dorst, Arjen B. Blom, Desiree L. Bos, Thomas Vogl, Sander W. Tas, Pilar Jimenez-Royo, Mats Bergstrom, Matthew Cleveland, Peter M. van der Kraan, Peter Laverman, Marije I. Koenders, Peter L. van Lent, Martijn H. J. van den Bosch
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-15 (2023)
Abstract Background Rheumatoid arthritis (RA) is one of the most prevalent and debilitating joint diseases worldwide. RA is characterized by synovial inflammation (synovitis), which is linked to the development of joint destruction. Magnetic resonanc
Externí odkaz:
https://doaj.org/article/2aad6123f8ac4ee5adcf05a7f4fb72f2
Akademický článek
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Autor:
Meike von Wulffen, Veronika Luehrmann, Stefanie Robeck, Antonella Russo, Lena Fischer-Riepe, Martijn van den Bosch, Peter van Lent, Karin Loser, Dmitry I. Gabrilovich, Sven Hermann, Johannes Roth, Thomas Vogl
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 113006- (2023)
Summary: Immune-suppressive effects of myeloid-derived suppressor cells (MDSCs) are well characterized during anti-tumor immunity. The complex mechanisms promoting MDSC development and their regulatory effects during autoimmune diseases are less unde
Externí odkaz:
https://doaj.org/article/8b2865b65c60489d869aa0d309545a05
Autor:
Snow, Michael, Van lent, Jan
This paper focuses on the Monge-Kantorovich formulation of the optimal transport problem and the associated $L^2$ Wasserstein distance. We use the $L^2$ Wasserstein distance in the Nearest Neighbour (NN) machine learning architecture to demonstrate t
Externí odkaz:
http://arxiv.org/abs/1804.03531
Autor:
Natália Valdrighi, Arjen B. Blom, Henk M. van Beuningen, Elly L. Vitters, Monique M. Helsen, Birgitte Walgreen, Peter L.E.M. van Lent, Marije I. Koenders, Peter M. van der Kraan, Fons A.J. van de Loo, Esmeralda N. Blaney Davidson
Publikováno v:
PeerJ, Vol 11, p e15482 (2023)
Background Osteoarthritis (OA) is a progressive joint disease and a major cause of chronic pain in adults. The prevalence of OA is higher in female patients, who tend to have worse OA outcomes, partially due to pain. The association between joint pai
Externí odkaz:
https://doaj.org/article/03fdaf6af3ba4d28bb9268a02e580afc
Autor:
Joyce Aarts, Arjan van Caam, Xinlai Chen, Renoud J. Marijnissen, Monique M. Helsen, Birgitte Walgreen, Elly L. Vitters, Fons A. van de Loo, Peter L. van Lent, Peter M. van der Kraan, Marije I. Koenders
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract TGF-β1 is an important growth factor to promote the differentiation of T helper 17 (Th17) and regulatory T cells (Treg). The potential of TGF-β1 as therapeutic target in T cell-mediated diseases like rheumatoid arthritis (RA) is unclear. W
Externí odkaz:
https://doaj.org/article/e56341f6fbb745499f284ebee7d9f397