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pro vyhledávání: '"van Kappel, Eline C"'
Publikováno v:
British Journal of Pharmacology, 174(24), 4575. Wiley-Blackwell
The β-catenin destruction complex is a dynamic cytosolic multiprotein assembly that provides a key node in Wnt signalling regulation. The core components of the destruction complex comprise the scaffold proteins axin and adenomatous polyposis coli a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b89c77687e89c0e7e2ed0b9feae02a9c
https://dspace.library.uu.nl/handle/1874/361523
https://dspace.library.uu.nl/handle/1874/361523
Akademický článek
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Autor:
Anvarian, Zeinab, Nojima, Hisashi, van Kappel, Eline C, Madl, Tobias, Spit, Maureen, Viertler, Martin, Jordens, Ingrid, Low, Teck Y, van Scherpenzeel, Revina C, Kuper, Ineke, Richter, Klaus, Heck, Albert J R, Boelens, Rolf, Vincent, Jean-Paul, Rüdiger, Stefan G D, Maurice, Madelon M, NMR Spectroscopy, Biomolecular Mass Spectrometry and Proteomics, Cellular Protein Chemistry, Sub NMR Spectroscopy, Sub Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Sub Cellular Protein Chemistry
Publikováno v:
Nature Structural and Molecular Biology, 23(4), 324. Nature Publishing Group
Nature Structural and Molecular Biology, 23, 324. Nature Publishing Group
Nat. Struct. Mol. Biol. 23, 324-332 (2016)
Nature Structural and Molecular Biology, 23, 324. Nature Publishing Group
Nat. Struct. Mol. Biol. 23, 324-332 (2016)
Signaling cascades depend on scaffold proteins that regulate the assembly of multiprotein complexes. Missense mutations in scaffold proteins are frequent in human cancer, but their relevance and mode of action are poorly understood. Here we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6c3a5dbf5adba98488c7ca3489d201
https://dspace.library.uu.nl/handle/1874/334617
https://dspace.library.uu.nl/handle/1874/334617
Publikováno v:
British Journal of Pharmacology; Dec2017, Vol. 174 Issue 24, p4575-4588, 14p
Akademický článek
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Autor:
Anvarian Z; Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., Nojima H; The Francis Crick Institute, Mill Hill, London, UK., van Kappel EC; Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., Madl T; NMR Spectroscopy Research Group, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands.; Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany and Biomolecular NMR spectroscopy, Technische Universität München, Garching, Germany.; Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.; Omics Center Graz, BioTechMed Graz, Graz, Austria., Spit M; Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., Viertler M; Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany and Biomolecular NMR spectroscopy, Technische Universität München, Garching, Germany., Jordens I; Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., Low TY; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands.; The Netherlands Proteomics Center, Utrecht, the Netherlands., van Scherpenzeel RC; Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., Kuper I; Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., Richter K; Department of Chemistry, Technische Universität München, Garching, Germany., Heck AJ; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands.; The Netherlands Proteomics Center, Utrecht, the Netherlands., Boelens R; NMR Spectroscopy Research Group, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, the Netherlands., Vincent JP; The Francis Crick Institute, Mill Hill, London, UK., Rüdiger SG; Cellular Protein Chemistry, Bijvoet Centre for Biomolecular Research, Utrecht University, Utrecht, the Netherlands., Maurice MM; Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
Publikováno v:
Nature structural & molecular biology [Nat Struct Mol Biol] 2016 Apr; Vol. 23 (4), pp. 324-32. Date of Electronic Publication: 2016 Mar 14.