Zobrazeno 1 - 10
of 1 497
pro vyhledávání: '"van Hilten A"'
Autor:
Rima Mustafa, Michelle M. J. Mens, Arno van Hilten, Jian Huang, Gennady Roshchupkin, Tianxiao Huan, Linda Broer, Joyce B. J. van Meurs, Paul Elliott, Daniel Levy, M. Arfan Ikram, Marina Evangelou, Abbas Dehghan, Mohsen Ghanbari
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-26 (2024)
Abstract Background MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene expression. Perturbations in plasma miRNA levels are known to impact disease risk and have potential as disease biomarkers. Exploring the genet
Externí odkaz:
https://doaj.org/article/625b253401c940869bcf67b3973bd481
Autor:
Arno van Hilten, Jeroen van Rooij, BIOS consortium, M. Arfan Ikram, Wiro J. Niessen, Joyce. B. J. van Meurs, Gennady V. Roshchupkin
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Integrating multi-omics data into predictive models has the potential to enhance accuracy, which is essential for precision medicine. In this study, we developed interpretable predictive models for multi-omics data by employing neural networ
Externí odkaz:
https://doaj.org/article/296197b7ce774b4fbd8e3012971c3fd4
Autor:
Daniele Bizzarri, Marcel J.T. Reinders, Lieke Kuiper, Marian Beekman, Joris Deelen, Joyce B.J. van Meurs, Jenny van Dongen, René Pool, Dorret I. Boomsma, Mohsen Ghanbari, Lude Franke, Pieternella E. Slagboom, Erik B. van den Akker, J.M. Geleijnse, E. Boersma, W.E. van Spil, M.M.J. van Greevenbroek, C.D.A. Stehouwer, C.J.H. van der Kallen, I.C.W. Arts, F. Rutters, J.W.J. Beulens, M. Muilwijk, P.J.M. Elders, L.M. 't Hart, M. Ghanbari, M.A. Ikram, M.G. Netea, M. Kloppenburg, Y.F.M. Ramos, N. Bomer, I. Meulenbelt, K. Stronks, M.B. Snijder, A.H. Zwinderman, B.T. Heijmans, L.H. Lumey, C. Wijmenga, J. Fu, A. Zhernakova, J. Deelen, S.P. Mooijaart, M. Beekman, P.E. Slagboom, G.L.J. Onderwater, A.M.J.M. van den Maagdenberg, G.M. Terwindt, C. Thesing, M. Bot, B.W.J.H. Penninx, S. Trompet, J.W. Jukema, N. Sattar, I.C.C. van der Horst, P. van der Harst, C. So-Osman, J.A. van Hilten, R.G.H.H. Nelissen, I.E. Höfer, F.W. Asselbergs, P. Scheltens, C.E. Teunissen, W.M. van der Flier, J. van Dongen, R. Pool, A.H.M. Willemsen, D.I. Boomsma, H.E.D. Suchiman, J.J.H. Barkey Wolf, D. Cats, H. Mei, M. Slofstra, M. Swertz, M.J.T. Reinders, E.B. van den Akker
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105279- (2024)
Summary: Background: 1H-NMR metabolomics and DNA methylation in blood are widely known biomarkers predicting age-related physiological decline and mortality yet exert mutually independent mortality and frailty signals. Methods: Leveraging multi-omics
Externí odkaz:
https://doaj.org/article/dd2f1125885a4ef2be328f0b36ea785b
Autor:
Geleijnse, J.M., Boersma, E., van Spil, W.E., van Greevenbroek, M.M.J., Stehouwer, C.D.A., van der Kallen, C.J.H., Arts, I.C.W., Rutters, F., Beulens, J.W.J., Muilwijk, M., Elders, P.J.M., 't Hart, L.M., Ghanbari, M., Ikram, M.A., Netea, M.G., Kloppenburg, M., Ramos, Y.F.M., Bomer, N., Meulenbelt, I., Stronks, K., Snijder, M.B., Zwinderman, A.H., Heijmans, B.T., Lumey, L.H., Wijmenga, C., Fu, J., Zhernakova, A., Deelen, J., Mooijaart, S.P., Beekman, M., Slagboom, P.E., Onderwater, G.L.J., van den Maagdenberg, A.M.J.M., Terwindt, G.M., Thesing, C., Bot, M., Penninx, B.W.J.H., Trompet, S., Jukema, J.W., Sattar, N., van der Horst, I.C.C., van der Harst, P., So-Osman, C., van Hilten, J.A., Nelissen, R.G.H.H., Höfer, I.E., Asselbergs, F.W., Scheltens, P., Teunissen, C.E., van der Flier, W.M., van Dongen, J., Pool, R., Willemsen, A.H.M., Boomsma, D.I., Suchiman, H.E.D., Barkey Wolf, J.J.H., Cats, D., Mei, H., Slofstra, M., Swertz, M., Reinders, M.J.T., van den Akker, E.B., Bizzarri, Daniele, Reinders, Marcel J.T., Kuiper, Lieke, Beekman, Marian, Deelen, Joris, van Meurs, Joyce B.J., van Dongen, Jenny, Pool, René, Boomsma, Dorret I., Ghanbari, Mohsen, Franke, Lude, Slagboom, Pieternella E., van den Akker, Erik B.
Publikováno v:
In eBioMedicine September 2024 107
Autor:
van Hilten, Arno1 (AUTHOR) a.vanhilten@erasmusmc.nl, van Rooij, Jeroen2 (AUTHOR), Heijmans, Bastiaan T.3 (AUTHOR), 't Hoen, Peter A. C.4 (AUTHOR), Meurs, Joyce van2 (AUTHOR), Jansen, Rick5 (AUTHOR), Franke, Lude6 (AUTHOR), Boomsma, Dorret I.7 (AUTHOR), Pool, René7 (AUTHOR), van Dongen, Jenny7 (AUTHOR), Hottenga, Jouke J.7 (AUTHOR), van Greevenbroek, Marleen M. J.8 (AUTHOR), Stehouwer, Coen D. A.8 (AUTHOR), van der Kallen, Carla J. H.8 (AUTHOR), Schalkwijk, Casper G.8 (AUTHOR), Wijmenga, Cisca6 (AUTHOR), Zhernakova, Sasha6 (AUTHOR), Tigchelaar, Ettje F.6 (AUTHOR), Slagboom, P. Eline3 (AUTHOR), Beekman, Marian3 (AUTHOR)
Publikováno v:
NPJ Systems Biology & Applications. 8/2/2024, Vol. 10 Issue 1, p1-10. 10p.
Autor:
Harry Warner, Giulia Franciosa, Guus van der Borg, Britt Coenen, Felix Faas, Claire Koenig, Rinse de Boer, René Classens, Sjors Maassen, Maksim V. Baranov, Shweta Mahajan, Deepti Dabral, Frans Bianchi, Niek van Hilten, Herre Jelger Risselada, Wouter H. Roos, Jesper Velgaard Olsen, Laia Querol Cano, Geert van den Bogaart
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113866- (2024)
Summary: To mount an adaptive immune response, dendritic cells must migrate to lymph nodes to present antigens to T cells. Critical to 3D migration is the nucleus, which is the size-limiting barrier for migration through the extracellular matrix. Her
Externí odkaz:
https://doaj.org/article/9c2fb1e58e4947c0a6fa89aaeb80c8a8
Autor:
Warner, Harry, Franciosa, Giulia, van der Borg, Guus, Coenen, Britt, Faas, Felix, Koenig, Claire, de Boer, Rinse, Classens, René, Maassen, Sjors, Baranov, Maksim V., Mahajan, Shweta, Dabral, Deepti, Bianchi, Frans, van Hilten, Niek, Risselada, Herre Jelger, Roos, Wouter H., Olsen, Jesper Velgaard, Cano, Laia Querol, van den Bogaart, Geert
Publikováno v:
In Cell Reports 26 March 2024 43(3)
Akademický článek
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Akademický článek
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Autor:
Maria Fiorella Contarino, Ed J Kuijper, Andrea E van der Meulen-de Jong, Josbert J Keller, Jacobus J van Hilten, Jelle J Goeman, Hein W Verspaget, Karuna EW Vendrik, Vlada O Chernova, Elisabeth M Terveer, Joffrey van Prehn, Eric KL Berssenbrugge, Jannie GE Henderickx, Martijn P Bauer, Romy D Zwittink
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Introduction Experimental studies suggest a role of gut microbiota in the pathophysiology of Parkinson’s disease (PD) via the gut–brain axis. The gut microbiota can also influence the metabolism of levodopa, which is the mainstay of treatment of
Externí odkaz:
https://doaj.org/article/a1f26c1154924ebd886a4fa9d984ae94