The effect of red blood cell transfusion on platelet function in critically ill patients

Autor: van Hezel, Maike E., van Manen, Lisa, Boshuizen, Margit, Straat, Marleen, De Cuyper, Iris M., Beuger, Boukje, Nieuwland, Rienk, Tanck, Michael W.T., de Korte, Dirk, Zwaginga, Jaap Jan, van Bruggen, Robin, Juffermans, Nicole P.

Publikováno v: In Thrombosis Research December 2019 184:115-121

Pathogenesis of non-antibody mediated transfusion-related acute lung injury from bench to bedside

Autor: Peters, Anna L., van Hezel, Maike E., Juffermans, Nicole P., Vlaar, Alexander P.J.

Publikováno v: In Blood Reviews January 2015 29(1):51-61

Effect of red cell transfusion on the host immune response in critically ill patients

Autor: van Hezel, Maike E.

In this thesis we investigated the effect of RBC transfusion on the host immune response. We conclude that RBC transfusions in critically ill patients are associated with an inflammatory and procoagulant host response. Activated neutrophils, monocyte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::f7e659708622c222cb26cf5bcc69942a
https://pure.amc.nl/en/publications/effect-of-red-cell-transfusion-on-the-host-immune-response-in-critically-ill-patients(cf806cfa-2f8d-4001-b538-ca483546532d).html

The effect of red blood cell transfusion on iron metabolism in critically ill patients

Autor: Boshuizen, Margit, van Hezel, Maike E, van Manen, Lisa, Straat, Marleen, Somsen, Yvemarie B O, Spoelstra-de Man, Angelique M E, Blumberg, Neil, van Bruggen, Robin, Juffermans, Nicole P

Publikováno v: Transfusion, 59(4):CP310, 1196-1201. Wiley-Blackwell
Boshuizen, M, van Hezel, M E, van Manen, L, Straat, M, Somsen, Y B O, Spoelstra-de Man, A M E, Blumberg, N, van Bruggen, R & Juffermans, N P 2019, ' The effect of red blood cell transfusion on iron metabolism in critically ill patients ', Transfusion, vol. 59, no. 4, pp. 1196-1201 . https://doi.org/10.1111/trf.15127
Transfusion, 59(4), 1196-1201. Wiley-Blackwell

BACKGROUND: Anemia of inflammation (AI) has a high prevalence in critically ill patients. In AI, iron metabolism is altered, as high levels of inflammation-induced hepcidin reduce the amount of iron available for erythropoiesis. AI is treated with re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::906443db54b18f28ef1a7b7dedc73a02
https://pure.amc.nl/en/publications/the-effect-of-red-blood-cell-transfusion-on-iron-metabolism-in-critically-ill-patients(0ad7e285-9967-4374-b0ec-b4569970fd87).html

Transfusion of 35-day-stored red blood cells does not alter lipopolysaccharide tolerance during human endotoxemia

Autor: Peters, Anna L., van Hezel, Maike E., Klanderman, Robert B., Tuip-de Boer, Anita M., Wiersinga, W. Joost, van der Spek, Anne H., van Bruggen, Robin, de Korte, Dirk, Juffermans, Nicole P., Vlaar, Alexander P. J.

Publikováno v: Transfusion, 57(6), 1359-1368. Wiley-Blackwell

Transfusion-related immunomodulation (TRIM) encompasses immunosuppressive and proinflammatory effects induced by red blood cell (RBC) transfusion. Changes that occur during storage in the RBC product have been hypothesized to underlie TRIM, mediated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::19f02c7a118a8d356d07a8c9e1cffaca
https://pure.amc.nl/en/publications/transfusion-of-35daystored-red-blood-cells-does-not-alter-lipopolysaccharide-tolerance-during-human-endotoxemia(2155a808-1ddf-4689-b477-fa3af6e5b604).html