Výsledky vyhledávání - "van Haastert, PJM"

Uniform cAMP stimulation of Dictyostelium cells induces localized patches of signal transduction and pseudopodia

Autor: Postma, Marten, Roelofs, J, Goedhart, J, Gadella, TWJ, Visser, AJWG, Van Haastert, PJM, Gadella, Theodorus W.J., Visser, Antonie J.W.G.

Publikováno v: Molecular Biology of the Cell, 14(12), 5019-5027. American Society for Cell Biology
Molecular Biology of the Cell, 14, 5019-5027
Molecular Biology of the Cell 14 (2003)
Molecular Biology of the Cell, 14(12), 5019-5027. AMER SOC CELL BIOLOGY

The chemoattractant cAMP induces the translocation of cytosolic PHCrac-GFP to the plasma membrane. PHCrac-GFP is a green fluorescent protein fused to a PH domain that presumably binds to phosphatydylinositol polyphosphates in the membrane. We determi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d6c48683e9075adac13b06fbbe3f14
https://doi.org/10.1091/mbc.e03-08-0566

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Chemoattractant-stimulated calcium influx in Dictyostelium discoideum does not depend on cGMP

Autor: Veltman, DM, De Boer, JS, Van Haastert, PJM, Boer, Jan Sietse de

Publikováno v: Biochimica et Biophysica Acta-General Subjects, 1623(2-3), 129-134. ELSEVIER SCIENCE BV

Chemoattractant stimulation of Dictyostelium cells leads to the opening of calcium channels in the plasma membrane, causing extracellular calcium to flux into the cell. The genetically uncharacterised mutants stimF and K18 show strongly altered chemo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db977272bdd7056542cd16799d4f9a9
https://hdl.handle.net/11370/64cbfdb2-fd51-48a8-92b7-ab4a1752fea4

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A diverse family of inositol 5-phosphatases playing a role in growth and development in Dictyostelium discoideum

Autor: Loovers, HM, Veenstra, K, Snippe, H, Pesesse, [No Value], Erneux, C, van Haastert, PJM, Loovers, Harriët M., Pesesse, Xavier

Publikováno v: The Journal of Biological Chemistry, 278(8), 5652-5658. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC

Inositol phosphate-containing molecules play an important role in a broad range of cellular processes. Inositol 5-phosphatases participate in the regulation of these signaling molecules. We have identified four inositol 5-phosphatases in Dictyosteliu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc183838776c5f1b3024b57c26cedda8
https://hdl.handle.net/11370/8ee5ec95-2dcf-4809-aa76-d2c7b219e22d

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Phosducin-like proteins in Dictyostelium discoideum: implications for the phosducin family of proteins

Autor: Blaauw, M, Knol, JC, Kortholt, A, Roelofs, J, (Engel), Ruchira, Postma, Marten, Visser, AJWG, Van Haastert, PJM, Knol, Jaco C., Visser, Antonie J.W.G.

Publikováno v: The EMBO Journal 22 (2003) 19
The EMBO Journal, 22(19), 5047-5057
EMBO Journal, 22(19), 5047-5057. Wiley

Retinal phosducin is known to sequester transducin Gbetagamma, thereby modulating transducin activity. Phos ducin is a member of a family of phosducin-like proteins (PhLP) found in eukaryotes. Phylogeny of 33 phosducin-like proteins from metazoa, pla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0afe48f85cb1953c5d4b69856e967fe6
https://doi.org/10.1093/emboj/cdg508

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Genomics: Genes lost during evolution

Autor: Roelofs, J, Van Haastert, PJM

Publikováno v: Nature, 411(6841), 1013-1014. Nature Publishing Group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::94cd0d756a2397278075a921314cf2e1
https://research.rug.nl/en/publications/d745494f-ade4-43a0-a334-db8bafc2d80a

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CGMP as second messenger during Dictyostelium chemotaxis

Autor: Van Haastert, PJM, Roelofs, J, Kuwayama, H, Thiery, JP

Publikováno v: MOLECULAR MECHANISMS OF TRANSCELLULAR SIGNALING, 134-141
STARTPAGE=134;ENDPAGE=141;TITLE=MOLECULAR MECHANISMS OF TRANSCELLULAR SIGNALING

The chemoattractant cAMP induces directed cell locomotion in Dictyostelium cells. Several second messenger pathways are activated upon binding of cAMP to G-protein-coupled receptors, inducting adenylyl cyclase, guanylyl cyclase, phospholipase C, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::a44198dd4b61b2cd860ec24862232a42
https://research.rug.nl/en/publications/7d9b373d-f145-4d57-ac95-71df57813c27

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Biochemistry and genetics of inositol phosphate metabolism in Dictyostelium

Autor: Van Haastert, PJM, Van Dijken, P., Thiery, JP

Publikováno v: MOLECULAR MECHANISMS OF TRANSCELLULAR SIGNALING, 75-84
STARTPAGE=75;ENDPAGE=84;TITLE=MOLECULAR MECHANISMS OF TRANSCELLULAR SIGNALING

Biochemical and genetic data on the metabolism of inositol phosphates in the micro-organism Dictyostelium are combined in a scheme composed of in five subroutes. The first subroute is the inositol cycle as found in other organisms: inositol is incorp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::b53f050ad36cfd807a14e510b88da66c
https://research.rug.nl/en/publications/16041f8f-10ca-4f25-bb76-fd8f48636915

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