mRNA-1273 vaccinated inflammatory bowel disease patients receiving TNF inhibitors develop broad and robust SARS-CoV-2-specific CD8 ⁺ T cell responses.

Autor: van den Dijssel J; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands., Duurland MC; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Konijn VA; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Kummer LY; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Department of Neurology and Neurophysiology, Amsterdam Neuroscience, Amsterdam UMC Location AMC, University of Amsterdam, Amsterdam, Netherlands., Hagen RR; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands., Kuijper LH; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Wieske L; Department of Neurology and Neurophysiology, Amsterdam Neuroscience, Amsterdam UMC Location AMC, University of Amsterdam, Amsterdam, Netherlands; Department of Clinical Neurophysiology, St Antonius Hospital, Nieuwegein, Netherlands., van Dam KP; Department of Neurology and Neurophysiology, Amsterdam Neuroscience, Amsterdam UMC Location AMC, University of Amsterdam, Amsterdam, Netherlands., Stalman EW; Department of Neurology and Neurophysiology, Amsterdam Neuroscience, Amsterdam UMC Location AMC, University of Amsterdam, Amsterdam, Netherlands., Steenhuis M; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Geerdes DM; Sanquin Reagents B.V., Amsterdam, Netherlands., Mok JY; Sanquin Reagents B.V., Amsterdam, Netherlands., Kragten AH; Sanquin Reagents B.V., Amsterdam, Netherlands., Menage C; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Koets L; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; National Screening Laboratory of Sanquin, Research and Laboratory Services, Amsterdam, Netherlands., Veldhuisen B; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Department of Immunohematology Diagnostics, Sanquin Diagnostic Services, Amsterdam, Netherlands., Verstegen NJ; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., van der Schoot CE; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands., van Esch WJ; Sanquin Reagents B.V., Amsterdam, Netherlands., D'Haens GR; Department of Gastroenterology and Hepatology, Amsterdam UMC Location AMC, University of Amsterdam, Amsterdam, Netherlands., Löwenberg M; Department of Gastroenterology and Hepatology, Amsterdam UMC Location AMC, University of Amsterdam, Amsterdam, Netherlands., Volkers AG; Department of Gastroenterology and Hepatology, Amsterdam UMC Location AMC, University of Amsterdam, Amsterdam, Netherlands., Rispens T; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Kuijpers TW; Department of Pediatric Immunology, Rheumatology and Infectious Disease, University of Amsterdam, Amsterdam, Netherlands., Eftimov F; Department of Neurology and Neurophysiology, Amsterdam Neuroscience, Amsterdam UMC Location AMC, University of Amsterdam, Amsterdam, Netherlands., van Gisbergen KP; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands., van Ham SM; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Swammerdam Institute for Life Sciences, University of Amsterdam, Netherlands., Ten Brinke A; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., van de Sandt CE; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia. Electronic address: cvandesandt@unimelb.edu.au.

Publikováno v: Journal of autoimmunity [J Autoimmun] 2024 Apr; Vol. 144, pp. 103175. Date of Electronic Publication: 2024 Feb 21.

Hobit and Blimp-1 instruct the differentiation of iNKT cells into resident-phenotype lymphocytes after lineage commitment.

Autor: Kragten NA; Dept. of Hematopoiesis, Sanquin Research and Landsteiner Laboratory Amsterdam UMC, Amsterdam, The Netherlands., Taggenbrock RL; Dept. of Hematopoiesis, Sanquin Research and Landsteiner Laboratory Amsterdam UMC, Amsterdam, The Netherlands., Parga Vidal L; Dept. of Hematopoiesis, Sanquin Research and Landsteiner Laboratory Amsterdam UMC, Amsterdam, The Netherlands., van Lier RA; Dept. of Hematopoiesis, Sanquin Research and Landsteiner Laboratory Amsterdam UMC, Amsterdam, The Netherlands., Stark R; Dept. of Hematopoiesis, Sanquin Research and Landsteiner Laboratory Amsterdam UMC, Amsterdam, The Netherlands.; Dept. of Experimental Immunology, Amsterdam UMC, Amsterdam, The Netherlands., van Gisbergen KP; Dept. of Hematopoiesis, Sanquin Research and Landsteiner Laboratory Amsterdam UMC, Amsterdam, The Netherlands.; Dept. of Experimental Immunology, Amsterdam UMC, Amsterdam, The Netherlands.

Publikováno v: European journal of immunology [Eur J Immunol] 2022 Mar; Vol. 52 (3), pp. 389-403. Date of Electronic Publication: 2022 Jan 09.

A non-canonical function of Ezh2 preserves immune homeostasis.

Autor: Vasanthakumar A; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia., Xu D; Institute of Ageing Research, Hangzhou Normal University School of Medicine, Hangzhou, China.; Hudson Institute of Medical Research, Monash University, Clayton, Vic., Australia.; Department of Molecular and Translational Science, Monash University, Clayton, Vic., Australia., Lun AT; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia., Kueh AJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia., van Gisbergen KP; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia., Iannarella N; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia., Li X; Institute of Ageing Research, Hangzhou Normal University School of Medicine, Hangzhou, China.; Hudson Institute of Medical Research, Monash University, Clayton, Vic., Australia.; Department of Molecular and Translational Science, Monash University, Clayton, Vic., Australia., Yu L; Hudson Institute of Medical Research, Monash University, Clayton, Vic., Australia.; Department of Molecular and Translational Science, Monash University, Clayton, Vic., Australia., Wang D; Hudson Institute of Medical Research, Monash University, Clayton, Vic., Australia.; Department of Molecular and Translational Science, Monash University, Clayton, Vic., Australia., Williams BR; Hudson Institute of Medical Research, Monash University, Clayton, Vic., Australia.; Department of Molecular and Translational Science, Monash University, Clayton, Vic., Australia., Lee SC; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia., Majewski IJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia., Godfrey DI; Department of Microbiology and Immunology, The University of Melbourne, Parkville, Vic., Australia.; ARC Centre of Excellence for Advanced Molecular Imaging, The University of Melbourne, Parkville, Vic., Australia., Smyth GK; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.; Department of Mathematics and Statistics, The University of Melbourne, Parkville, Vic., Australia., Alexander WS; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia., Herold MJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia., Kallies A; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia., Nutt SL; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia nutt@wehi.edu.au rallan@wehi.edu.au.; Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia., Allan RS; The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia nutt@wehi.edu.au rallan@wehi.edu.au.; Department of Medical Biology, The University of Melbourne, Parkville, Vic., Australia.

Publikováno v: EMBO reports [EMBO Rep] 2017 Apr; Vol. 18 (4), pp. 619-631. Date of Electronic Publication: 2017 Feb 21.

Granzyme A impairs host defense during Streptococcus pneumoniae pneumonia.

Autor: van den Boogaard FE; Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; f.e.vandenboogaard@amc.nl., van Gisbergen KP; Laboratory of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands;, Vernooy JH; Department of Respiratory Medicine, University Maastricht, The Netherlands;, Medema JP; Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Laboratory of Experimental Oncology and Radiobiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;, Roelofs JJ; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;, van Zoelen MA; Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;, Endeman H; Department of Internal Medicine, St. Antonius Hospital, Nieuwegein, The Netherlands;, Biesma DH; Department of Internal Medicine, St. Antonius Hospital, Nieuwegein, The Netherlands;, Boon L; Bioceros, Utrecht, The Netherlands; and., Van't Veer C; Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;, de Vos AF; Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;, van der Poll T; Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Medicine, Division of Infectious Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2016 Aug 01; Vol. 311 (2), pp. L507-16. Date of Electronic Publication: 2016 Jun 24.

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.

Autor: Mackay LK; Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia. Australian Research Council (ARC) Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, Australia. lkmackay@unimelb.edu.au kallies@wehi.edu.au k.vangisbergen@sanquin.nl., Minnich M; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria., Kragten NA; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, Netherlands., Liao Y; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. Department of Medical Biology, The University of Melbourne, Melbourne, Australia., Nota B; Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, AMC, University of Amsterdam, Amsterdam, Netherlands., Seillet C; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. Department of Medical Biology, The University of Melbourne, Melbourne, Australia., Zaid A; Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Man K; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. Department of Medical Biology, The University of Melbourne, Melbourne, Australia., Preston S; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. Department of Medical Biology, The University of Melbourne, Melbourne, Australia., Freestone D; Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Braun A; Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Wynne-Jones E; Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Behr FM; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, Netherlands. The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. Department of Medical Biology, The University of Melbourne, Melbourne, Australia. Department of Experimental Immunology, AMC, Amsterdam, Netherlands., Stark R; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, Netherlands., Pellicci DG; Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia. Australian Research Council (ARC) Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, Australia., Godfrey DI; Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia. Australian Research Council (ARC) Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, Australia., Belz GT; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. Department of Medical Biology, The University of Melbourne, Melbourne, Australia., Pellegrini M; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. Department of Medical Biology, The University of Melbourne, Melbourne, Australia., Gebhardt T; Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Busslinger M; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria., Shi W; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. Department of Computing and Information Systems, The University of Melbourne, Melbourne, Australia., Carbone FR; Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., van Lier RA; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, Netherlands., Kallies A; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. Department of Medical Biology, The University of Melbourne, Melbourne, Australia. lkmackay@unimelb.edu.au kallies@wehi.edu.au k.vangisbergen@sanquin.nl., van Gisbergen KP; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, Netherlands. The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. Department of Medical Biology, The University of Melbourne, Melbourne, Australia. Department of Experimental Immunology, AMC, Amsterdam, Netherlands. lkmackay@unimelb.edu.au kallies@wehi.edu.au k.vangisbergen@sanquin.nl.

Publikováno v: Science (New York, N.Y.) [Science] 2016 Apr 22; Vol. 352 (6284), pp. 459-63.