TransCatheter aortic valve implantation and fractional flow reserve-guided percutaneous coronary intervention versus conventional surgical aortic valve replacement and coronary bypass grafting for treatment of patients with aortic valve stenosis and complex or multivessel coronary disease (TCW): an international, multicentre, prospective, open-label, non-inferiority, randomised controlled trial.

Autor: Kedhi E; Royal Victoria Hospital, McGill University Health Center, Montreal, QC, Canada; Department of Cardiology and Structural Heart Disease, Medical University of Silesia, Katowice, Poland. Electronic address: elvin.kedhi@mcgill.ca., Hermanides RS; Department of Cardiology, Isala Heart Center, Zwolle, Netherlands., Dambrink JE; Department of Cardiology, Isala Heart Center, Zwolle, Netherlands., Singh SK; Department of Thoracic Surgery, Isala Heart Center, Zwolle, Netherlands., Ten Berg JM; Department of Cardiology, St Antonius Hospital, Nieuwegein, Netherlands; Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, Netherlands., van Ginkel D; Department of Cardiology, St Antonius Hospital, Nieuwegein, Netherlands; Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, Netherlands., Hudec M; Stredoslovenský Ústav Srdcových a Cievnych Chorôb, Banská, Bystrica, Slovakia., Amoroso G; Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands., Amat-Santos IJ; Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Madrid, Spain; Hospital Clínico Universitario de Valladolid, Valladolid, Spain., Andreas M; Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria., Campante Teles R; Hospital de Santa Cruz, Carnaxide, Portugal; Comprehensive Health Research Center, Nova Medical School, Lisbon, Portugal., Bonnet G; Hôpital haut Lévêque, Unite Médico Chirurgicale, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France., Van Belle E; Department of Cardiology, Department of Interventional Cardiology for Coronary, Valves and Structural Heart Diseases and Institut Coeur Poumon, Centre Hospitalier Universitaire Lille, Lille, France; INSERM U1011, Lille, France; Université de Lille, Lille, France., Conradi L; Klinik und Poliklinik für Herz- und Gefäßchirurgie, Universitäres Herz- und Gefäßzentrum Hamburg, Hamburg, Germany., van Garsse L; Department of Cardiothoracic Surgery, Radboud University Medical Centre, Nijmegen, Netherlands., Wojakowski W; Department of Cardiology and Structural Heart Disease, Medical University of Silesia, Katowice, Poland., Voudris V; Interventional Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece., Sacha J; Department of Cardiology, University Hospital, Institute of Medical Sciences, University of Opole, Opole, Poland; Faculty of Physical Education and Physiotherapy, Opole University of Technology, Opole, Poland., Cervinka P; 1st Department Medicine-Cardioangiology, Charles University Prague, Medical Faculty and University Hospital Hradec Kralove, Prague, Czech Republic; University of Jan Evangelista Purkyne, Usti nad Labem, Czech Republic., Lipsic E; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands., Somi S; Department of Cardiology, Haga Hospital, The Hague, Netherlands., Nombela-Franco L; Cardiovascular Institute, Hospital Clínico San Carlos IdISSC, Madrid, Spain., Postma S; Diagram Research, Zwolle, Netherlands., Piayda K; Department of Cardiology and Vascular Medicine, Medical Faculty, Justus-Liebig-University Giessen, Giessen, Germany., De Luca G; Division of Cardiology, Azienda Ospedaliera Universitaria Policlinico Gaetano Martino, University of Messina, Messina, Italy; Division of Cardiology, IRCCS Hospital Galeazzi-Sant'Ambrogio, Milan, Italy., Kolkman E; Diagram Research, Zwolle, Netherlands., Malinowski KP; Center for Digital Medicine and Robotics, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland; Department of Bioinformatics and Telemedicine, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland., Modine T; Hôpital haut Lévêque, Unite Médico Chirurgicale, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France.

Publikováno v: Lancet (London, England) [Lancet] 2025 Dec 21; Vol. 404 (10471), pp. 2593-2602. Date of Electronic Publication: 2024 Dec 04.