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Role of N-Glycosylation in FcγRIIIa interaction with IgG

Autor: Van Coillie, Julie, Schulz, Morten A, Bentlage, Arthur E H, de Haan, Noortje, Ye, Zilu, Geerdes, Dionne M, van Esch, Wim J E, Hafkenscheid, Lise, Miller, Rebecca L, Narimatsu, Yoshiki, Vakhrushev, Sergey Y, Yang, Zhang, Vidarsson, Gestur, Clausen, Henrik, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics

Publikováno v: Van Coillie, J, Schulz, M A, Bentlage, A E H, de Haan, N, Ye, Z, Geerdes, D M, van Esch, W J E, Hafkenscheid, L, Miller, R L, Narimatsu, Y, Vakhrushev, S Y, Yang, Z, Vidarsson, G & Clausen, H 2022, ' Role of N-Glycosylation in FcγRIIIa interaction with IgG ', Frontiers in Immunology, vol. 13, 987151 . https://doi.org/10.3389/fimmu.2022.987151
Frontiers in Immunology, 13. Frontiers Media S.A.

Immunoglobulins G (IgG) and their Fc gamma receptors (FcγRs) play important roles in our immune system. The conservedN-glycan in the Fc region of IgG1 impacts interaction of IgG with FcγRs and the resulting effector functions, which has led to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ccca2c4803fb5b83a8aecdd963c1bb3
https://doi.org/10.3389/fimmu.2022.987151

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Parallel detection of SARS-CoV-2 epitopes reveals dynamic immunodominance profiles of CD8+ T memory cells in convalescent COVID-19 donors

Autor: van den Dijssel, Jet, Hagen, Ruth R., de Jongh, Rivka, Steenhuis, Maurice, Rispens, Theo, Geerdes, Dionne M., Mok, Juk Yee, Kragten, Angela H. M., Duurland, Mariël C., Verstegen, Niels J. M., van Ham, S. Marieke, van Esch, Wim J. E., van Gisbergen, Klaas P. JM, Hombrink, Pleun, ten Brinke, Anja, van de Sandt, Carolien E.

Publikováno v: Clinical & translational immunology, 11(10):e1423. Nature Publishing Group

Objectives: High-magnitude CD8+ T cell responses are associated with mild COVID-19 disease; however, the underlying characteristics that define CD8+ T cell-mediated protection are not well understood. The antigenic breadth and the immunodominance hie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::94e4c6891d9289b6fe1c446bcd847707
https://pure.amc.nl/en/publications/parallel-detection-of-sarscov2-epitopes-reveals-dynamic-immunodominance-profiles-of-cd8-t-memory-cells-in-convalescent-covid19-donors(6829a925-fcc6-4dea-a0d2-a1ed2869ea00).html