P32 - Topic: AS04-MDS Biology and Pathogenesis/AS04h-Immune deregulation: HIGH-DIMENSIONAL PROFILING OF T AND NK CELL FREQUENCIES AND UNSUPERVISED CLUSTERING ANALYSES TO IDENTIFY IMMUNE (DYS) FUNCTIONAL PHENOTYPES IN MDS PATIENTS

Autor: Van Ens, D., Brummelman, J., Van Eck Van Der Sluijs, J., Woestenenk, R., Heister, D., Koorenhof-Scheele, T., Langemeijer, S., Jansen, J., Dolstra, H., Hobo, W.

Publikováno v: In Leukemia Research September 2021 108 Supplement

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Interleukin-1β induces trained innate immunity in human hematopoietic progenitor cells in vitro.

Autor: Flores-Gomez D; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, Gelderland, the Netherlands., Hobo W; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, 6525 GA Nijmegen, Gelderland, the Netherlands., van Ens D; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, 6525 GA Nijmegen, Gelderland, the Netherlands., Kessler EL; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, Gelderland, the Netherlands; Laboratory for Experimental Cardiology, Department of Cardiology, University Medical Center, Utrecht, 3584 CX Utrecht, the Netherlands., Novakovic B; Murdoch Children's Research Institute and Department of Pediatrics, University of Melbourne, Royal Children's Hospital, Parkville, VIC 3052, Australia., Schaap NPM; Department of Hematology, Radboud University Medical Center, 6525 GA Nijmegen, Gelderland, the Netherlands., Rijnen WHC; Department of Orthopedics, Radboud University Medical Center, 6525 GA Nijmegen, Gelderland, the Netherlands., Joosten LAB; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, Gelderland, the Netherlands; Department of Medical Genetics, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca 400347, Romania., Netea MG; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, Gelderland, the Netherlands; Department of Immunology and Metabolism, Life and Medical Sciences Institute, University of Bonn, 53115 Bonn, Germany., Riksen NP; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, Gelderland, the Netherlands. Electronic address: niels.riksen@radboudumc.nl., Bekkering S; Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, Gelderland, the Netherlands.

Publikováno v: Stem cell reports [Stem Cell Reports] 2024 Sep 25. Date of Electronic Publication: 2024 Sep 25.