Zobrazeno 1 - 10
of 60
pro vyhledávání: '"van Eijkeren, J.C."'
Publikováno v:
In Toxicology Letters September 2021 350 Supplement:S133-S133
Autor:
Hunault, C.C., van Eijkeren, J.C., Mensinga, T.T., de Vries, I., Leenders, M.E.C., Meulenbelt, J., Risk Assessment of Toxic and Immunomodulatory Agents, Dep IRAS
Publikováno v:
Toxicology and Applied Pharmacology, 246(3), 148. Academic Press Inc.
Introduction No model exists to describe the disposition and kinetics of inhaled cannabis containing a high THC dose. We aimed to develop a kinetic model providing estimates of the THC serum concentrations after smoking cannabis cigarettes containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565bd7c0bcb068d7ff32dad818bda312
https://doi.org/10.1016/j.taap.2010.04.019
https://doi.org/10.1016/j.taap.2010.04.019
Autor:
Hunault, C.C., van Eijkeren, J.C., Mensinga, T.T., de Vries, I., Leenders, M.E.C., Meulenbelt, J.
Introduction No model exists to describe the disposition and kinetics of inhaled cannabis containing a high THC dose. We aimed to develop a kinetic model providing estimates of the THC serum concentrations after smoking cannabis cigarettes containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______101::106905fb5d95b8bc9038cade86172cbf
https://dspace.library.uu.nl/handle/1874/204715
https://dspace.library.uu.nl/handle/1874/204715
Autor:
Bosgra, S., van Eijkeren, J.C., van der Schans, M.J., Langenberg, J.P., Slob, W., Risk Assessment of Toxic and Immunomodulatory Agents, Dep IRAS
Publikováno v:
Toxicology and Applied Pharmacology, 236(1), 9. Academic Press Inc.
Theoretical work has shown that the isobole method is not generally valid as a method for testing the absence or presence of interaction (in the biochemical sense) between chemicals. The present study illustrates how interaction can be tested by fitt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::d024e5b318e6d15333eecaaa03521afc
https://dspace.library.uu.nl/handle/1874/39449
https://dspace.library.uu.nl/handle/1874/39449
Autor:
ter Laak, T.L., van Eijkeren, J.C., Busser, F., van Leeuwen, H.P., Hermens, J.L.M., Risk Assessment of Toxic and Immunomodulatory Agents, Dep Biologie, Dep IRAS
Publikováno v:
Environmental Science and Technology, 43(5), 1379. American Chemical Society
The exchange rate of hydrophobic organic chemicals between the aqueous phase and a sorbent (e.g., soil, organism, passive sampler) is relevant for distribution processes between environmental compartments, including organisms. Dissolved phases such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::a28dd09ef60d3fa2bad680a4e494f579
https://dspace.library.uu.nl/handle/1874/39485
https://dspace.library.uu.nl/handle/1874/39485
Autor:
Treijtel, N., van Eijkeren, J.C., Nijmeijer, S., de Greef-van der Sandt, I.C., Freidig, A., Risk Assessment of Toxic and Immunomodulatory Agents, Dep IRAS
Publikováno v:
Toxicology in Vitro, 23(1), 185. NLM (Medline)
The metabolism and active transport of ritonavir and saquinavir were studied using sandwich-cultured rat hepatoyctes and rat liver microsomes. For ritonavir four comparable metabolites were observed in the sandwich-culture and in microsomes. For saqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::68cc0907fe6c98a1fd2a675926c2880d
https://dspace.library.uu.nl/handle/1874/39432
https://dspace.library.uu.nl/handle/1874/39432
Autor:
Bosgra, S., van Eijkeren, J.C., van der Schans, M.J., Langenberg, J.P., Slob, W., Risk Assessment of Toxic and Immunomodulatory Agents, Dep IRAS
Publikováno v:
Toxicology and Applied Pharmacology, 236(1), 1. Academic Press Inc.
The applicability of dose addition to combinations of OP-esters and carbamates has been questioned based on theoretical considerations, but these have not been well supported by experimental findings. In the present study, the inhibition of AChE by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::e94d75e5a922b6ca61d1c86bb9c007b2
https://dspace.library.uu.nl/handle/1874/39444
https://dspace.library.uu.nl/handle/1874/39444
Autor:
Bosgra, S., van Eijkeren, J.C., Slob, W., Risk Assessment of Toxic and Immunomodulatory Agents, Dep IRAS
Publikováno v:
Critical Reviews in Toxicology, 39(5), 418. Informa Healthcare
The prediction of the effect of cumulative exposure to similarly acting chemicals is commonly done by dose addition, such as in the relative potency factor approach. This can only be done under the assumption of zero interaction between the chemicals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::3b72f36f95148ab0551595a7d7b97afc
https://dspace.library.uu.nl/handle/1874/39414
https://dspace.library.uu.nl/handle/1874/39414
Autor:
Yang, Fang1 (AUTHOR) jinyangguang1999@126.com, Zhang, Mei1 (AUTHOR), Jin, Yang-Guang1 (AUTHOR), Chen, Jun-Cheng1 (AUTHOR), Duan, Ming-Hui1 (AUTHOR), Liu, Yue1 (AUTHOR), Li, Ze-En1 (AUTHOR), Li, Xing-Ping1 (AUTHOR), Yang, Fan1 (AUTHOR) yfscau@126.com
Publikováno v:
Animals (2076-2615). May2023, Vol. 13 Issue 9, p1512. 14p.
Autor:
Quach, Tam T.1,2 (AUTHOR), Stratton, Harrison J.3 (AUTHOR), Khanna, Rajesh4 (AUTHOR), Mackey-Alfonso, Sabrina1 (AUTHOR), Deems, Nicolas1 (AUTHOR), Honnorat, Jérome2,5,6 (AUTHOR), Meyer, Kathrin7,8 (AUTHOR), Duchemin, Anne-Marie9 (AUTHOR) anne-marie.duchemin@osumc.edu
Publikováno v:
International Journal of Molecular Sciences. Nov2022, Vol. 23 Issue 22, p14188. 25p.