Systematic update to the mammalian relative potency estimate database and development of best estimate toxic equivalency factors for dioxin-like compounds.

Autor: Fitch S; ToxStrategies, Katy, TX, USA. Electronic address: sfitch@toxstrategies.com., Blanchette A; ToxStrategies, Asheville, NC, USA., Haws LC; ToxStrategies, Austin, TX, USA., Franke K; ToxStrategies, Asheville, NC, USA., Ring C; ToxStrategies, Austin, TX, USA., DeVito M; Environmental Protection Agency, Center for Computational Toxicology and Exposure, Research Triangle Park, NC, USA., Wheeler M; National Institute of Environmental Health Sciences/National Institutes of Health, Research Triangle Park, NC, USA., Walker N; National Institute of Environmental Health Sciences/National Institutes of Health, Research Triangle Park, NC, USA., Birnbaum L; National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA; Nicholas School of the Environment, Duke University, Durham, NC, USA., Van Ede KI; KeyToxicology, Arnhem, the Netherlands., Antunes Fernandes EC; KeyToxicology, Arnhem, the Netherlands., Wikoff DS; ToxStrategies, Asheville, NC, USA.

Publikováno v: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2024 Feb; Vol. 147, pp. 105571. Date of Electronic Publication: 2024 Jan 18.

Relative effect potency estimates of dioxin-like activity for dioxins, furans, and dioxin-like PCBs in adults based on cytochrome P450 1A1 and 1B1 gene expression in blood.

Autor: Wimmerová S; Slovak Medical University, Limbová 14, 83303 Bratislava, Slovakia. Electronic address: sona.wimmerova@szu.sk., van den Berg M; Institute for Risk Assessment Sciences (IRAS), Utrecht University, P.O. Box 80.176, 3508, TD, Utrecht, The Netherlands. Electronic address: m.vandenberg@uu.nl., Chovancová J; Slovak Medical University, Limbová 14, 83303 Bratislava, Slovakia. Electronic address: jana.chovancova@szu.sk., Patayová H; Slovak Medical University, Limbová 14, 83303 Bratislava, Slovakia. Electronic address: henrieta.patayova@szu.sk., Jusko TA; Departments of Public Health Sciences and Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA. Electronic address: todd_jusko@urmc.rochester.edu., van Duursen MB; Institute for Risk Assessment Sciences (IRAS), Utrecht University, P.O. Box 80.176, 3508, TD, Utrecht, The Netherlands. Electronic address: m.vanduursen@uu.nl., Palkovičová Murínová Ľ; Slovak Medical University, Limbová 14, 83303 Bratislava, Slovakia. Electronic address: lubica.murinova@szu.sk., Canton RF; Institute for Risk Assessment Sciences (IRAS), Utrecht University, P.O. Box 80.176, 3508, TD, Utrecht, The Netherlands. Electronic address: rfcanton@gmail.com., van Ede KI; Institute for Risk Assessment Sciences (IRAS), Utrecht University, P.O. Box 80.176, 3508, TD, Utrecht, The Netherlands. Electronic address: K.I.vanEde@uu.nl., Trnovec T; Slovak Medical University, Limbová 14, 83303 Bratislava, Slovakia. Electronic address: tomas.trnovec@szu.sk.

Publikováno v: Environment international [Environ Int] 2016 Nov; Vol. 96, pp. 24-33. Date of Electronic Publication: 2016 Aug 31.

Consensus toxicity factors for polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls combining in silico models and extensive in vitro screening of AhR-mediated effects in human and rodent cells.

Autor: Larsson M; †Department of Chemistry, Umeå University, SE-901 87 Umeå, Sweden., van den Berg M; ‡Endocrine Toxicology Group, Institute for Risk Assessment Sciences, Utrecht University, P.O. Box 80177, NL-3508 TD Utrecht, The Netherlands., Brenerová P; #Department of Chemistry and Toxicology, Veterinary Research Institute, 621 32 Brno, Czech Republic., van Duursen MB; ‡Endocrine Toxicology Group, Institute for Risk Assessment Sciences, Utrecht University, P.O. Box 80177, NL-3508 TD Utrecht, The Netherlands., van Ede KI; ‡Endocrine Toxicology Group, Institute for Risk Assessment Sciences, Utrecht University, P.O. Box 80177, NL-3508 TD Utrecht, The Netherlands., Lohr C; ⊥Department of Food Chemistry and Environmental Toxicology, University of Kaiserslautern, Kaiserslautern 67663, Germany., Luecke-Johansson S; §Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden., Machala M; #Department of Chemistry and Toxicology, Veterinary Research Institute, 621 32 Brno, Czech Republic., Neser S; ⊥Department of Food Chemistry and Environmental Toxicology, University of Kaiserslautern, Kaiserslautern 67663, Germany., Pěnčíková K; #Department of Chemistry and Toxicology, Veterinary Research Institute, 621 32 Brno, Czech Republic., Poellinger L; §Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden., Schrenk D; ⊥Department of Food Chemistry and Environmental Toxicology, University of Kaiserslautern, Kaiserslautern 67663, Germany., Strapáčová S; #Department of Chemistry and Toxicology, Veterinary Research Institute, 621 32 Brno, Czech Republic., Vondráček J; #Department of Chemistry and Toxicology, Veterinary Research Institute, 621 32 Brno, Czech Republic.; ∥Department of Cytokinetics, Institute of Biophysics AS CR, 612 65 Brno, Czech Republic., Andersson PL; †Department of Chemistry, Umeå University, SE-901 87 Umeå, Sweden.

Publikováno v: Chemical research in toxicology [Chem Res Toxicol] 2015 Apr 20; Vol. 28 (4), pp. 641-50. Date of Electronic Publication: 2015 Feb 13.

Differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells.

Autor: van Ede KI; Institute for Risk Assessment Sciences, Utrecht University, Yalelaan 104, 3584 CM Utrecht, The Netherlands. Electronic address: k.i.vanede@uu.nl., Gaisch KP; Institute for Risk Assessment Sciences, Utrecht University, Yalelaan 104, 3584 CM Utrecht, The Netherlands. Electronic address: konrad_gaisch@yahoo.co.uk., van den Berg M; Institute for Risk Assessment Sciences, Utrecht University, Yalelaan 104, 3584 CM Utrecht, The Netherlands. Electronic address: m.vandenberg@uu.nl., van Duursen MB; Institute for Risk Assessment Sciences, Utrecht University, Yalelaan 104, 3584 CM Utrecht, The Netherlands. Electronic address: m.vanduursen@uu.nl.

Publikováno v: Toxicology letters [Toxicol Lett] 2014 Apr 07; Vol. 226 (1), pp. 43-52. Date of Electronic Publication: 2014 Jan 26.

Tissue distribution of dioxin-like compounds: potential impacts on systemic relative potency estimates.

Autor: van Ede KI; Institute for Risk Assessment Sciences, Utrecht University, Yalelaan 104, 3584 CM Utrecht, The Netherlands. k.i.vanede@uu.nl, Aylward LL, Andersson PL, van den Berg M, van Duursen MB

Publikováno v: Toxicology letters [Toxicol Lett] 2013 Jul 18; Vol. 220 (3), pp. 294-302. Date of Electronic Publication: 2013 May 13.