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Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.

Autor: Hofman DA; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, the Netherlands.; These authors contributed equally., Ruiz-Orera J; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany.; These authors contributed equally., Yannuzzi I; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Murugesan R; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Brown A; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Current address: Arbor Biotechnologies, Cambridge, MA, 02140, USA., Clauser KR; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Condurat AL; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., van Dinter JT; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, the Netherlands., Engels SAG; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, the Netherlands., Goodale A; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., van der Lugt J; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, the Netherlands., Abid T; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Wang L; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Zhou KN; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Current address: Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, CA, 91101, USA., Vogelzang J; Department of Pathology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02215, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, 02215, USA., Ligon KL; Department of Pathology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02215, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, 02215, USA.; Department of Pathology, Boston Children's Hospital, Boston MA 02115., Phoenix TN; Division of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, 45229, USA., Roth JA; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Root DE; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Hubner N; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany.; Charité-Universitätsmedizin, 10117 Berlin, Germany.; German Centre for Cardiovascular Research, Partner Site Berlin, 13347 Berlin, Germany., Golub TR; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA., Bandopadhayay P; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA., van Heesch S; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, the Netherlands., Prensner JR; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA.; Current address: Department of Pediatrics, Division of Pediatric Hematology/Oncology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 06. Date of Electronic Publication: 2023 May 06.