Zobrazeno 1 - 10
of 312
pro vyhledávání: '"van De Winkel JG"'
Publikováno v:
Nature Biotechnology. 18:48-51
We constructed an immunotoxin, composed of an antibody directed against the high-affinity IgG receptor CD64 and Ricin-A, with the aim of resolving chronic inflammation through elimination of activated macrophages. In vitro, this immunotoxin proved ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fadec8dc7e3f119c100b6cd801636980
https://doi.org/10.1038/71908
https://doi.org/10.1038/71908
Publikováno v:
Immunogenetics. 49:586-589
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e90775d9ebab20613230e025f2080ae4
https://doi.org/10.1007/s002510050544
https://doi.org/10.1007/s002510050544
Publikováno v:
Frontiers in Bioscience. 1:a25-33
Phagocytes bear more than one class of receptors for the Fc domain of IgG (FcgammaR). In addition the same ligand can interact with different classes of FcgammaR. This complexity makes it difficult to study the contribution of the various classes of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d0b717395bf30c561ee1865c195fc70
https://doi.org/10.2741/a102
https://doi.org/10.2741/a102
Autor:
van Spriel Ab, van de Winkel Jg, van Hattum J, van Amersfoort Es, Kuiper J, van Egmond M, van Garderen E, Damen Ca, van Zandbergen G
Publikováno v:
Nature medicine. 6(6)
Despite the well-recognized involvement of immunoglobulin (Ig) A in mucosal immunity, the function of its receptor, FcalphaRI (CD89), is poorly understood. The ability of FcalphaRI to activate leukocytes seems to conflict with the proposed anti-infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82de10fe4ac9224dbc2a1be74fd54029
https://pubmed.ncbi.nlm.nih.gov/10835685
https://pubmed.ncbi.nlm.nih.gov/10835685
Publikováno v:
British journal of haematology. 94(1)
IgG antibodies to the Rh D polypeptide on red cells are normally IgG1 or IgG3, whereas antibodies produced in response to carbohydrate antigens such as the A and B blood groups are predominantly IgG2. The consequences of this isotype restriction for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e56c3748afc7c338432308c52f316b
https://pubmed.ncbi.nlm.nih.gov/8757532
https://pubmed.ncbi.nlm.nih.gov/8757532
Autor:
van de Winkel Jg, Lammerts van Bueren Jj, Thomas Valerius, Brännström A, Paul W. H. I. Parren, Wim K. Bleeker, Magnus Jansson, Tanja Schneider-Merck, Matthias Peipp
Publikováno v:
Proceedings of the National Academy of Sciences. 109:5548-5548
The epidermal growth factor receptor (EGFR) activates cellular pathways controlling cell proliferation, differentiation, migration, and survival. It thus represents a valid therapeutic target for treating solid cancers. Here, we used an electron micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93889725ebf37843c160582c5792df16
https://doi.org/10.1073/pnas.1203736109
https://doi.org/10.1073/pnas.1203736109
Akademický článek
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Akademický článek
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Autor:
Valerius, T, Repp, R, de Wit, TP, Berthold, S, Platzer, E, Kalden, JR, Gramatzki, M, van de Winkel, JG
Publikováno v:
Blood; August 1993, Vol. 82 Issue: 3 p931-939, 9p
Publikováno v:
Blood; April 1992, Vol. 79 Issue: 7 p1651-1656, 6p