Antibody Aggregation: A Problem Within the Biopharmaceutical Industry and Its Role in AL Amyloidosis Disease.

Autor: Sheehan K; Trinity Biomedical Sciences Institute (TBSI), School of Biochemistry & Immunology, Trinity College Dublin, The University of Dublin, Dublin 2, Ireland.; School of Genetics & Microbiology, Trinity College Dublin, The University of Dublin, Dublin 2, Ireland., Jeon H; Trinity Biomedical Sciences Institute (TBSI), School of Biochemistry & Immunology, Trinity College Dublin, The University of Dublin, Dublin 2, Ireland.; Lonza Biologics Tuas Pte. Ltd., 35 Tuas South Ave 6, Singapore, 637377, Republic of Singapore., Corr SC; School of Genetics & Microbiology, Trinity College Dublin, The University of Dublin, Dublin 2, Ireland.; School of Microbiology and APC Microbiome Ireland, University College Cork, Cork, Ireland., Hayes JM; Trinity Biomedical Sciences Institute (TBSI), School of Biochemistry & Immunology, Trinity College Dublin, The University of Dublin, Dublin 2, Ireland., Mok KH; Trinity Biomedical Sciences Institute (TBSI), School of Biochemistry & Immunology, Trinity College Dublin, The University of Dublin, Dublin 2, Ireland. mok1@tcd.ie.; Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College Dublin, The University of Dublin, Dublin 2, Ireland. mok1@tcd.ie.

Publikováno v: The protein journal [Protein J] 2024 Nov 11. Date of Electronic Publication: 2024 Nov 11.

Resolution of cutaneous inflammation after local elimination of macrophages

Autor: Kiekens Rc, T. Thepen, Vooijs Wc, van Vuuren Aj, van de Winkel Jg, Damen Ca

Publikováno v: Nature Biotechnology. 18:48-51

We constructed an immunotoxin, composed of an antibody directed against the high-affinity IgG receptor CD64 and Ricin-A, with the aim of resolving chronic inflammation through elimination of activated macrophages. In vitro, this immunotoxin proved ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fadec8dc7e3f119c100b6cd801636980
https://doi.org/10.1038/71908

Phagocytosis and intracellular killing of serum-opsonized Staphylococcus aureus by mouse fibroblasts expressing human Fcgamma receptor type IIa CD32

Autor: van de Winkel Jg, Geertsma Mf, Jansen R, Nibbering Ph, Broug-Holub E, Bezemer Ac

Publikováno v: Frontiers in Bioscience. 1:a25-33

Phagocytes bear more than one class of receptors for the Fc domain of IgG (FcgammaR). In addition the same ligand can interact with different classes of FcgammaR. This complexity makes it difficult to study the contribution of the various classes of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d0b717395bf30c561ee1865c195fc70
https://doi.org/10.2741/a102

IgA Nephropathy: Emerging Mechanisms of Disease.

Autor: Roberts, Lydia E.^1,2, Williams, Chloe E. C.^3,4, Oni, Louise⁵, Barratt, Jonathan^1,2, Selvaskandan, Haresh^1,2 hs328@leicester.ac.uk

Publikováno v: Indian Journal of Nephrology. Jul/Aug2024, Vol. 34 Issue 4, p297-309. 13p.

A predictive nomogram for short‐term outcomes of myasthenia gravis patients treated with low‐dose rituximab.

Autor: Zhou, Yufan^1,2,3 (AUTHOR), Guo, Rongjing⁴ (AUTHOR), Xia, Xingyu^1,2,3 (AUTHOR), Jing, Sisi⁵ (AUTHOR), Lu, Jun^1,2,3 (AUTHOR), Ruan, Zhe⁴ (AUTHOR), Luo, Sushan^1,2,3 (AUTHOR), Huan, Xiao^1,2,3 (AUTHOR), Zhao, Chongbo^1,2,3 (AUTHOR), Chang, Ting⁴ (AUTHOR) changting1981@163.com, Xi, Jianying^1,2,3 (AUTHOR) xijianying@fudan.edu.cn

Publikováno v: CNS Neuroscience & Therapeutics. May2024, Vol. 30 Issue 5, p1-9. 9p.