Zobrazeno 1 - 10 of 303 pro vyhledávání: '"van Dam, AD"'
1
Akademický článek
Inconsistency in ferritin reference intervals across laboratories: a major concern for clinical decision making.
Autor: Kurstjens S; Laboratory of Clinical Chemistry and Hematology, 10233 Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.; Laboratory of Clinical Chemistry and Laboratory Medicine, Dicoon BV, Location Canisius Wilhelmina Hospital, Nijmegen, The Netherlands., van Dam AD; Laboratory of Clinical Chemistry and Hematology, 10233 Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.; Department of Clinical Chemistry and Hematology, Elisabeth-Tweesteden Hospital, Tilburg, The Netherlands.; Department of Laboratory Medicine, Radboudumc, Nijmegen, The Netherlands., Oortwijn E; Laboratory of Clinical Chemistry and Hematology, Atalmedial Diagnostic Centre, Amsterdam, The Netherlands., den Elzen WPJ; Department of Laboratory Medicine, Laboratory Specialized Diagnostics & Research, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute and Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands., Candido F; General Practitioner Health Centre Rijnland, Alrijne Hospital, Leiderdorp, The Netherlands., Kusters R; Laboratory of Clinical Chemistry and Hematology, 10233 Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.; Department of Health Technology and Services Research, Faculty of Behavioural, Management and Social Sciences, Technical Medical Centre, University of Twente, Enschede, The Netherlands., Schipper A; Laboratory of Clinical Chemistry and Hematology, 10233 Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.; Diagnostic Image Analysis Group, Radboudumc, Nijmegen, The Netherlands., Kortmann YFC; Department of Gastroenterology, 10233 Jeroen Bosch Hospital , 's-Hertogenbosch, The Netherlands., Herings RMC; PHARMO Institute for Drug Outcomes Research, Utrecht, The Netherlands.; Department of Epidemiology and Data Science, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Kok M; Saltro, Diagnostic Center for Primary Care, Unilabs NL, Utrecht, The Netherlands., Krabbe J; Laboratory of Clinical Chemistry and Hematology, Medisch Spectrum Twente/Unilabs BV, Enschede, The Netherlands., de Boer BA; Laboratory of Clinical Chemistry and Hematology, Atalmedial Diagnostic Centre, Amsterdam, The Netherlands., de Jong AM; Laboratory of Clinical Chemistry and Hematology, Atalmedial Diagnostic Centre, Amsterdam, The Netherlands., Frasa MAM; Laboratory of Clinical Chemistry and Hematology, 10233 Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.
Publikováno v: Clinical chemistry and laboratory medicine [Clin Chem Lab Med] 2024 Oct 14. Date of Electronic Publication: 2024 Oct 14.
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2
Akademický článek
Immunoproteasomal Inhibition With ONX-0914 Attenuates Atherosclerosis and Reduces White Adipose Tissue Mass and Metabolic Syndrome in Mice.
Autor: Schaftenaar FH; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., van Dam AD; Division of Endocrinology, Department of Medicine, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, the Netherlands (A.D.D., P.C.N.R.)., de Bruin G; Department of Chemical Biology, Leiden Institute of Chemistry, the Netherlands (G.d.B., B.I.F.)., Depuydt MAC; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., de Mol J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Amersfoort J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Douna H; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Meijer M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Kröner MJ; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., van Santbrink PJ; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Bernabé Kleijn MNA; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., van Puijvelde GHM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Florea BI; Department of Chemical Biology, Leiden Institute of Chemistry, the Netherlands (G.d.B., B.I.F.)., Slütter B; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Foks AC; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Bot I; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.)., Rensen PCN; Division of Endocrinology, Department of Medicine, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, the Netherlands (A.D.D., P.C.N.R.)., Kuiper J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, the Netherlands (F.H.S., M.A.C.D., J.d.M., J.A., H.D., M.M., M.J.K., P.J.v.S., M.N.A.B.K., G.H.M.v.P., B.S., A.C.F., I.B., J.K.).
Publikováno v: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2024 Jun; Vol. 44 (6), pp. 1346-1364. Date of Electronic Publication: 2024 Apr 25.
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3
Akademický článek
OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity.
Autor: Purvis GSD; Sir William Dunn School of Pathology, University of Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, British Heart Foundation Centre for Research Excellence, John Radcliffe Hospital, University of Oxford, Oxford, UK., Collino M; Dept of Neurosciences 'Rita Levi Montalcini' University of Turin, Turin, IT., van Dam AD; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Einaudi G; Pharmacology Unit, School of Pharmacy, University of Camerino, Camerino, Italy., Ng Y; Division of Cardiovascular Medicine, British Heart Foundation Centre for Research Excellence, John Radcliffe Hospital, University of Oxford, Oxford, UK.; National Institute for Health (NIHR) Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Shanmuganathan M; Division of Cardiovascular Medicine, British Heart Foundation Centre for Research Excellence, John Radcliffe Hospital, University of Oxford, Oxford, UK.; National Institute for Health (NIHR) Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Patel SY; Primary Immunodeficiency Unit, Department of Experimental Medicine, Nuffield Department of Medicine, University of Oxford, NIHR Oxford Biomedical Research Centre, Oxford, UK., Thiemermann C; The William Harvey Research Institute, Queen Mary University of London, London, UK., Channon KM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, British Heart Foundation Centre for Research Excellence, John Radcliffe Hospital, University of Oxford, Oxford, UK.; National Institute for Health (NIHR) Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Greaves DR; Sir William Dunn School of Pathology, University of Oxford, UK.
Publikováno v: Diabetes [Diabetes] 2024 Jan 08. Date of Electronic Publication: 2024 Jan 08.
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5
HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution
Autor: Kuo, F-C, Neville, MJ, Sabaratnam, R, Wesolowska-Andersen, A, Phillips, D, Wittemans, LBL, van Dam, AD, Loh, NY, Todorčević, M, Denton, N, Kentistou, KA, Joshi, PK, Christodoulides, C, Langenberg, C, Collas, P, Karpe, F, Pinnick, KE
Publikováno v: Kuo, F-C, Neville, M J, Sabaratnam, R, Wesolowska-Andersen, A, Phillips, D, Wittemans, L B L, van Dam, A D, Loh, N Y, Todorčević, M, Denton, N, Kentistou, K A, Joshi, P K, Christodoulides, C, Langenberg, C, Collas, P, Karpe, F & Pinnick, K E 2022, ' HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution ', Cell Reports, vol. 40, no. 4, 111136, pp. 111136 . https://doi.org/10.1016/j.celrep.2022.111136
Mechanisms governing regional human adipose tissue (AT) development remain undefined. Here, we show that the long non-coding RNA HOTAIR (HOX transcript antisense RNA) is exclusively expressed in gluteofemoral AT, where it is essential for adipocyte d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476f16b1c4b5fd39ca5abe1d0b406856
https://pubmed.ncbi.nlm.nih.gov/36131101
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6
Akademický článek
TCF7L2 plays a complex role in human adipose progenitor biology, which might contribute to genetic susceptibility to type 2 diabetes.
Autor: Verma M; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 7LE, UK., Loh NY; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 7LE, UK., Sabaratnam R; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 7LE, UK; Steno Diabetes Center Odense, Odense University Hospital, DK-5000 Odense, Denmark; Department of Clinical Research, University of Southern Denmark, DK-5000 Odense, Denmark., Vasan SK; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 7LE, UK., van Dam AD; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 7LE, UK., Todorčević M; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 7LE, UK., Neville MJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 7LE, UK., Toledo E; Department of Computational Biology, Novo Nordisk Research Centre Oxford, UK., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 7LE, UK; NIHR Oxford Biomedical Research Centre, OUH Foundation Trust, Oxford OX3 7LE, UK., Christodoulides C; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 7LE, UK; NIHR Oxford Biomedical Research Centre, OUH Foundation Trust, Oxford OX3 7LE, UK. Electronic address: costas.christodoulides@ocdem.ox.ac.uk.
Publikováno v: Metabolism: clinical and experimental [Metabolism] 2022 Aug; Vol. 133, pp. 155240. Date of Electronic Publication: 2022 Jun 10.
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7
Akademický článek
HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution.
Autor: Kuo FC; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Headington OX3 7LE, UK; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defence Medical Centre, Taipei, Taiwan., Neville MJ; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Headington OX3 7LE, UK; NIHR Oxford Biomedical Research Centre, OUH Foundation Trust, Oxford, UK., Sabaratnam R; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Headington OX3 7LE, UK; Institute of Clinical Research, University of Southern Denmark, 5000 Odense C, Denmark; Steno Diabetes Center Odense, Odense University Hospital, 5000 Odense C, Denmark., Wesolowska-Andersen A; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Phillips D; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Headington OX3 7LE, UK., Wittemans LBL; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK; The Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., van Dam AD; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Headington OX3 7LE, UK., Loh NY; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Headington OX3 7LE, UK., Todorčević M; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Headington OX3 7LE, UK., Denton N; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Headington OX3 7LE, UK., Kentistou KA; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK., Joshi PK; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK., Christodoulides C; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Headington OX3 7LE, UK., Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Collas P; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway; Department of Immunology, Oslo University Hospital, Oslo, Norway., Karpe F; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Headington OX3 7LE, UK; NIHR Oxford Biomedical Research Centre, OUH Foundation Trust, Oxford, UK. Electronic address: fredrik.karpe@ocdem.ox.ac.uk., Pinnick KE; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Headington OX3 7LE, UK. Electronic address: katherine.pinnick@ocdem.ox.ac.uk.
Publikováno v: Cell reports [Cell Rep] 2022 Jul 26; Vol. 40 (4), pp. 111136.
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8
Akademický článek
The role of autoantibodies in bridging obesity, aging, and immunosenescence.
Autor: Valentino, Taylor R.1 (AUTHOR), Chen, Nan2,3,4 (AUTHOR), Makhijani, Priya1 (AUTHOR), Khan, Saad3,4 (AUTHOR), Winer, Shawn2,5 (AUTHOR), Revelo, Xavier S.6,7 (AUTHOR), Winer, Daniel A.1,2,3,4,8,9 (AUTHOR) dwiner@buckinstitute.org
Publikováno v: Immunity & Ageing. 11/30/2024, Vol. 21 Issue 1, p1-25. 25p.
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9
Akademický článek
Depot-specific mRNA expression programs in human adipocytes suggest physiological specialization via distinct developmental programs.
Autor: Clemons, Heather J.1,2 (AUTHOR), Hogan, Daniel J.1,2 (AUTHOR) hogandj@alumni.stanford.edu, Brown, Patrick O.1,2 (AUTHOR) pbrown@stanford.edu
Publikováno v: PLoS ONE. 10/14/2024, Vol. 19 Issue 10, p1-35. 35p.
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10
Akademický článek
Higher Plasma Sclerostin and Lower Wnt Signaling Gene Expression in White Adipose Tissue of Prediabetic South Asian Men Compared with White Caucasian Men.
Autor: Janssen LGM; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands. l.g.m.janssen@lumc.nl., Van Dam AD; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Hanssen MJW; Department of Human Biology and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands., Kooijman S; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Nahon KJ; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Reinders H; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Jazet IM; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands., Van Marken Lichtenbelt WD; Department of Human Biology and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands., Rensen PCN; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Appelman-Dijkstra NM; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Center for Bone Quality, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands., Boon MR; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Publikováno v: Diabetes & metabolism journal [Diabetes Metab J] 2020 Apr; Vol. 44 (2), pp. 326-335. Date of Electronic Publication: 2019 Oct 31.
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