Hereditable variants of classical protein tyrosine phosphatase genes: Will they prove innocent or guilty?

Autor: Hendriks WJAJ; Department of Cell Biology, Radboud University Medical Centre, Nijmegen, The Netherlands., van Cruchten RTP; Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands., Pulido R; Biomarkers in Cancer Unit, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Ikerbasque, Basque Foundation for Science, Bilbao, Spain.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2023 Jan 23; Vol. 10, pp. 1051311. Date of Electronic Publication: 2023 Jan 23 (Print Publication: 2022).

A comprehensive atlas of fetal splicing patterns in the brain of adult myotonic dystrophy type 1 patients.

Autor: Degener MJF; Centre for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., van Cruchten RTP; Centre for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Otero BA; Department of Molecular Genetics and Microbiology, Center for NeuroGenetics, Genetics Institute, University of Florida, FL 32610-0266 Gainesville, FL, USA., Wang ET; Department of Molecular Genetics and Microbiology, Center for NeuroGenetics, Genetics Institute, University of Florida, FL 32610-0266 Gainesville, FL, USA., Wansink DG; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., 't Hoen PAC; Centre for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.

Publikováno v: NAR genomics and bioinformatics [NAR Genom Bioinform] 2022 Mar 08; Vol. 4 (1), pp. lqac016. Date of Electronic Publication: 2022 Mar 08 (Print Publication: 2022).

Recovery in the Myogenic Program of Congenital Myotonic Dystrophy Myoblasts after Excision of the Expanded (CTG) n Repeat.

Autor: André LM; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., van Cruchten RTP; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Willemse M; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Bezstarosti K; Proteomics Center, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands., Demmers JAA; Proteomics Center, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands., van Agtmaal EL; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Wansink DG; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands., Wieringa B; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2019 Nov 13; Vol. 20 (22). Date of Electronic Publication: 2019 Nov 13.

Expanded CUG repeats in DMPK transcripts adopt diverse hairpin conformations without influencing the structure of the flanking sequences.

Autor: van Cruchten RTP; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, 6525 GA, The Netherlands., Wieringa B; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, 6525 GA, The Netherlands., Wansink DG; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, 6525 GA, The Netherlands.

Publikováno v: RNA (New York, N.Y.) [RNA] 2019 Apr; Vol. 25 (4), pp. 481-495. Date of Electronic Publication: 2019 Jan 30.

The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model.

Autor: Kakkar V; Department of Cell Biology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, the Netherlands., Månsson C; Department of Biochemistry and Structural Biology, Center for Molecular Protein Science, Lund University, 221 00 Lund, Sweden., de Mattos EP; Department of Cell Biology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, the Netherlands; Department of Genetics, Federal University of Rio Grande do Sul, Porto Alegre 91501-970, Brazil., Bergink S; Department of Cell Biology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, the Netherlands., van der Zwaag M; Department of Cell Biology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, the Netherlands., van Waarde MAWH; Department of Cell Biology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, the Netherlands., Kloosterhuis NJ; Department of Pediatrics, Molecular Genetics Section, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, the Netherlands., Melki R; Neuroscience Paris-Saclay Institute of Neuroscience, Centre National de la Recherche Scientifique, 91190 Gif-Sur-Yvette, France., van Cruchten RTP; Department of Biochemistry and Structural Biology, Center for Molecular Protein Science, Lund University, 221 00 Lund, Sweden., Al-Karadaghi S; Department of Biochemistry and Structural Biology, Center for Molecular Protein Science, Lund University, 221 00 Lund, Sweden., Arosio P; Department of Chemistry, University of Cambridge, Cambridge CB2 1TN, UK., Dobson CM; Department of Chemistry, University of Cambridge, Cambridge CB2 1TN, UK., Knowles TPJ; Department of Chemistry, University of Cambridge, Cambridge CB2 1TN, UK., Bates GP; Department of Medical and Molecular Genetics, King's College London, London WC2R 2LS, UK., van Deursen JM; Mayo Clinic, Rochester, MN 55905, USA., Linse S; Department of Biochemistry and Structural Biology, Center for Molecular Protein Science, Lund University, 221 00 Lund, Sweden., van de Sluis B; Department of Pediatrics, Molecular Genetics Section, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, the Netherlands., Emanuelsson C; Department of Biochemistry and Structural Biology, Center for Molecular Protein Science, Lund University, 221 00 Lund, Sweden., Kampinga HH; Department of Cell Biology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, the Netherlands. Electronic address: h.h.kampinga@umcg.nl.

Publikováno v: Molecular cell [Mol Cell] 2016 Apr 21; Vol. 62 (2), pp. 272-283. Date of Electronic Publication: 2016 Apr 14.