HER-2/neu Amplification Testing in Breast Cancer by Multiplex Ligation-Dependent Probe Amplification in Comparison with Immunohistochemistry and In Situ Hybridization

Autor: Moelans, Cathy B., de Weger, Roel A., van Blokland, Marja T.M., Ezendam, Chantal, Elshof, Sabrina, Tilanus, Marcel G. J., van Diest, Paul J.

Publikováno v: Cellular Oncology, Vol 31, Iss 1, Pp 1-10 (2009)
Cellular Oncology : the Official Journal of the International Society for Cellular Oncology

Background: Assessment of HER-2/neu status in invasive breast cancer is crucial to establish eligibility for trastuzumab and taxane based chemotherapy. Next to immunohistochemistry (IHC) to evaluate protein overexpression, a second line gene amplific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4fe06b94f342d466ecb1dd2dd4112b59
https://doaj.org/article/94711039197844a190f01ba1b7778195