Výsledky vyhledávání - "van Beusechem V"

Targeting non-human coronaviruses to human cancer cells using a bispecific single-chain antibody

Autor: Würdinger, T, Verheije, M H, Raaben, M, Bosch, B J, de Haan, C A M, van Beusechem, V W, Rottier, P J M, Gerritsen, W R, LS Pathologie, LS Virologie, Emeriti TLC

Publikováno v: Gene Therapy, 12(18), 1394-1404. Nature Publishing Group
Gene Therapy
Gene Therapy, 12(18), 1394. Nature Publishing Group
Würdinger, T, Verheije, M H, Raaben, M, Bosch, B J, de Haan, C A M, van Beusechem, V W, Rottier, P J M & Gerritsen, W R 2005, ' Targeting non-human coronaviruses to human cancer cells using a bispecific single-chain antibody ', Gene Therapy, vol. 12, no. 18, pp. 1394-1404 . https://doi.org/10.1038/sj.gt.3302535

To explore the potential of using non-human coronaviruses for cancer therapy, we first established their ability to kill human tumor cells. We found that the feline infectious peritonitis virus (FIPV) and a felinized murine hepatitis virus (fMHV), bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6168d672db294e5480d531a66d0d07a1
https://hdl.handle.net/1871/26582

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Soluble receptor-mediated targeting of mouse hepatitis coronavirus to the human epidermal growth factor receptor

Autor: Würdinger, T, Verheije, M H, Broen, K, Bosch, B J, Haijema, B J, de Haan, C A M, van Beusechem, V W, Gerritsen, W R, Rottier, P J M, LS Pathologie, LS Virologie, Emeriti TLC

Publikováno v: Würdinger, T, Verheije, M H, Broen, K, Bosch, B J, Haijema, B J, de Haan, C A M, van Beusechem, V W, Rottier, P J M & Gerritsen, W R 2005, ' Soluble receptor-mediated targeting of mouse hepatitis coronavirus to the human epidermal growth factor receptor ', Journal of Virology, vol. 79, no. 24, pp. 15314-15322 . https://doi.org/10.1128/JVI.79.24.15314-15322.2005
Journal of Virology, 79(24), 15314-15322. American Society for Microbiology
Journal of Virology
Journal of Virology, 79(24), 15314. American Society for Microbiology

The mouse hepatitis coronavirus (MHV) infects murine cells by binding of its spike (S) protein to murine CEACAM1a. The N-terminal part of this cellular receptor (soR) is sufficient for S binding and for subsequent induction of the conformational chan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce67dbcc17a02b732a63b034bfc808ff
https://research.vumc.nl/en/publications/8104fb01-eb65-4319-8b7c-10e11a6bf5e0

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Epidermal growth factor receptor targeting of replication competent adenovirus enhances cytotoxicity in bladder cancer

Autor: van der Poel, H G, Molenaar, Bonnie, van Beusechem, V W, Haisma, H J, Rodriguez, R, Curiel, D T, Gerritsen, W R

Publikováno v: The Journal of Urology, 168(1), 266-72. Elsevier Inc.

PURPOSE: We evaluated the delivery and oncolytic potential of targeted replication competent adenoviruses in bladder cancer lines. MATERIALS AND METHODS: Seven established human bladder cancer tumor lines (5637, SW800, TCCsup, J82, Scaber, T24 and 25

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::f33ebc30f121158fc3b43b64abd7f3fa
https://research.vumc.nl/en/publications/395a6c0a-e273-4956-b935-8d3932b7af45

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Combined targeting of adenoviruses to integrins and epidermal growth factor receptors increases gene transfer into primary glioma cells and spheroids

Autor: Grill, Jacques, Van Beusechem, V W, Van Der Valk, P, Dirven, C M, Leonhart, A, Pherai, D S, Haisma, H J, Pinedo, H M, Curiel, D T, Gerritsen, W R

Publikováno v: Clinical Cancer Research, 7(3), 641-650. AMER ASSOC CANCER RESEARCH
Grill, J, Van Beusechem, V W, Van Der Valk, P, Dirven, C M, Leonhart, A, Pherai, D S, Haisma, H J, Pinedo, H M, Curiel, D T & Gerritsen, W R 2001, ' Combined targeting of adenoviruses to integrins and epidermal growth factor receptors increases gene transfer into primary glioma cells and spheroids ', Clinical Cancer Research, vol. 7, no. 3, pp. 641-50 .
Clinical Cancer Research, 7(3), 641-50. American Association for Cancer Research Inc.

Adenoviral-mediated gene transfer is suboptimal in human glioma and limits in vivo gene therapy approaches. There is a need for targeted vectors able to enhance gene transfer into the tumor as well as to lower the viral load in the surrounding normal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1fc1940a2b5d4f4e6e934e505f1d92dd
https://research.rug.nl/en/publications/6502706c-2af3-4158-abbc-cc4b5397f2b5

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Transductional targeting of adenoviral vectors to porstate cancer in vitro

Autor: Bangma VERVALLEN, CH, Kraaij, Robert, Rijswijk, A, Haisma, HJ, van Beusechem, V, Gerritsen, W

Publikováno v: Prostate Cancer and Prostatic Diseases, 2(3), 5-5. Nature Publishing Group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::f4f21d8835519ef147c4077474c7b96f
https://pure.eur.nl/en/publications/c3815765-e36c-4b91-a58a-46fe28b01fa1

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Intrinsic potential of human hemopoietic stem cells to self-renewal during EX vivo cultures

Autor: Knaan-Shanzer, S., Verlinden, S.F.F., Van Beusechem, V. W., Valerio, D.

Publikováno v: Knaan-Shanzer, S, Verlinden, S F F, Van Beusechem, V W & Valerio, D 1998, ' Intrinsic potential of human hemopoietic stem cells to self-renewal during EX vivo cultures ', Experimental Hematology, vol. 26, no. 8, pp. 737 .
Experimental Hematology, 26(8). Elsevier Inc.

Self-renewal of p I uri potential hemopoietic stem cells (HSCs) is a primary requirement for their ex vivo expansion as well as for the long-lasting genetic correction of the hemopoietic system. In our search for culture conditions that will facilita

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cdca7b20e1dd2d19a26670ba182a4669
https://research.vumc.nl/en/publications/dcf3321e-6737-4cca-a27a-5690a730c761

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Cell cycle state, response to hemopoietic growth factors and retroviral vector-mediated transduction of human hemopoietic stem cells

Autor: Knaän-Shanzer, S, Valerio, D, van Beusechem, V W

Publikováno v: Gene Therapy, 3(4), 323-33. Nature Publishing Group
Knaän-Shanzer, S, Valerio, D & van Beusechem, V W 1996, ' Cell cycle state, response to hemopoietic growth factors and retroviral vector-mediated transduction of human hemopoietic stem cells ', Gene Therapy, vol. 3, no. 4, pp. 323-33 .

A multi-parameter fluorometric analysis was applied to study in vitro proliferation and expansion of a candidate hemopoietic stem cell population, ie CD34brightLin cells. In primary hemopoietic cell samples the CD34brightLin population comprised on a

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https://research.vumc.nl/en/publications/e03dbb89-f950-4d0e-8332-d009771df34e

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