Zobrazeno 1 - 10 of 159 pro vyhledávání: '"van 't Veer LJ"'
1
Are ATM mutations 7271T-->G and IVS10-6T-->G really high-risk breast cancer-susceptibility alleles?
Autor: Szabo, CI, Schutte, Mieke, Broeks, A, Houwing-Duistermaat, JJ, Thorstenson, YR, Durocher, F, Oldenburg, Rogier, Wasielewski, M (Marijke), Odefrey, F, Thompson, D, Floore, AN, Kraan, J, Klijn, Jan, van den Ouweland, Ans, BRCA-X cons.coop.fam.reg.,, Int.disc.Health Res.int.breast,, Wagner, TMU, Devilee, P, Simard, J, van 't Veer, LJ (Laura), Goldgar, DE, Meijers-Heijboer, EJ
Publikováno v: Cancer Research, 64, 840-843. American Association for Cancer Research Inc.
Cancer research, 64(3), 840-843. American Association for Cancer Research Inc.
Two mutations of the ATM gene were recently suggested to confer breast cancer risks similar to mutations of BRCA1 or BRCA2. Here, we set out to confirm these findings in 961 families with non-BRCA1/BRCA2 breast cancer from diverse geographical region
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81541d2813eec29bf9ba65bb4a2287e7
https://doi.org/10.1158/0008-5472.CAN-03-2678
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2
Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk
Autor: Stevens, KN, Garcia-Closas, M, Fredericksen, Z, Kosel, M, Pankratz, VS, Hopper, JL, Dite, GS, Apicella, C, Southey, MC, Schmidt, MK, Broeks, A, Van 't Veer, LJ, Tollenaar, RAEM, Fasching, PA, Beckmann, MW, Hein, A, Ekici, AB, Johnson, N, Peto, J, dos Santos Silva, I, Gibson, L, Sawyer, E, Tomlinson, I, Kerin, MJ, Chanock, S, Lissowska, J, Hunter, DJ, Hoover, RN, Thomas, GD, Milne, RL, Arias Pérez, JI, González-Neira, A, Benítez, J, Burwinkel, B, Meindl, A, Schmutzler, RK, Bartrar, CR, Hamann, U, Ko, YD, Brüning, T, Chang-Claude, J, Hein, R, Wang-Gohrke, S, Dörk, T, Schürmann, P, Bremer, M, Hillemanns, P, Bogdanova, N, Zalutsky, JV, Rogov, YI, Antonenkova, N, Lindblom, A, Margolin, S, Mannermaa, A, Kataja, V, Kosma, V-M, Hartikainen, J, Chenevix-Trench, G, Chen, X, Peterlongo, P, Bonanni, B, Bernard, L, Manoukian, S, Wang, X, Cerhan, J, Vachon, CM, Olson, J, Giles, GG, Baglietto, L, McLean, CA, Severi, G, John, EM, Miron, A, Winqvist, R, Pylkäs, K, Jukkola-Vuorinen, A, Grip, M, Andrulis, I, Knight, JA, Glendon, G, Mulligan, AM, Cox, A, Brock, IW, Elliott, G, Cross, SS, Pharoah, PP, Dunning, AM, Pooley, KA, Humphreys, MK, Wang, J, Kang, D, Yoo, K-Y, Noh, D-Y, Sangrajrang, S, Gabrieau, V, Brennan, P, McKay, J, Anton-Culver, H, Ziogas, A, Couch, FJ
Publikováno v: British journal of cancer, vol 105, iss 12
BackgroundSomatic mutations in phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) are frequent in breast tumours and have been associated with oestrogen receptor (ER) expression, human epidermal growth factor receptor-2 overexpression, lymph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::335ef5ee3063b931f3ffc48a803c1e54
https://escholarship.org/uc/item/51z268qb
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3
Comparison of gene expression profiles predicting progression in breast cancer patients treated with tamoxifen
Autor: Kok, M, Linn, SC, Van Laar, RK, Jansen, Maurice, Berg, Tineke, Delahaye, LJMJ, Glas, AM, Peterse, JL, Hauptmann, M (Michael), Foekens, John, Klijn, Jan, Wessels, LFA, van 't Veer, LJ (Laura), Berns, Els
Publikováno v: Breast Cancer Research and Treatment, 113(2), 275-283. Springer New York
Background Molecular signatures that predict outcome in tamoxifen treated breast cancer patients have been identified. For the first time, we compared these response profiles in an independent cohort of (neo)adjuvant systemic treatment na < ve breast
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::dcc09e25184965270984e767010e1f94
https://pure.eur.nl/en/publications/e8548bc4-3996-4db1-85b5-d8ffaa7ceb9d
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5
Gene signature evaluation as a prognostic tool: challenges in the design of the MINDACT trial
Autor: Bines J, Marc Buyse, Sherene Loi, Patrick Therasse, Jan Bogaerts, J. Harrison, S. Mook, Decker N, Martine Piccart, Emiel J. Th. Rutgers, Fatima Cardoso, van 't Veer Lj, Peter M. Ravdin, Sofia Braga
Publikováno v: Nature clinical practice. Oncology. 3(10)
This Review describes the work conducted by the TRANSBIG consortium in the development of the MINDACT (Microarray In Node negative Disease may Avoid ChemoTherapy) trial. The goal of the trial is to provide definitive evidence regarding the clinical r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622b434dd5291da8fa446aa43c9b7916
https://pubmed.ncbi.nlm.nih.gov/17019432
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7
Akademický článek
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8
Akademický článek
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9
Akademický článek
ATM germline mutations in classical ataxia-telangiectasia patients in the Dutch population.
Autor: Broeks, A, de Klein, A, Floore, AN, Muijtjens, M, Kleijer, WJ, Jaspers, NG, van 't Veer, LJ
Publikováno v: Human Mutation; 1998, Vol. 12 Issue 5, p330-337, 8p
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