Zobrazeno 1 - 10
of 1 856
pro vyhledávání: '"vaccine trial"'
Autor:
Tim R. Mosmann, Jonathan A. Rebhahn, Stephen C. De Rosa, Michael C. Keefer, M. Juliana McElrath, Nadine G. Rouphael, Giuseppe Pantaleo, Peter B. Gilbert, Lawrence Corey, James J. Kobie, Juilee Thakar
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe HVTN 105 vaccine clinical trial tested four combinations of two immunogens - the DNA vaccine DNA-HIV-PT123, and the protein vaccine AIDSVAX B/E. All combinations induced substantial antibody and CD4+ T cell responses in many participa
Externí odkaz:
https://doaj.org/article/52dd5afd41534ef9921ac84b943b0929
Assessing the feasibility of Phase 3 vaccine trials against Marburg Virus Disease: A modelling study
Publikováno v:
Vaccine: X, Vol 14, Iss , Pp 100321- (2023)
Background: Outbreaks of Marburg virus disease (MVD) are rare and small in size, with only 18 recorded outbreaks since 1967, only two of which involved more than 100 cases. It has been proposed, therefore, that Phase 3 trials for MVD vaccines should
Externí odkaz:
https://doaj.org/article/64ca775fe0934a23b580f54d169c8be3
Autor:
Allahna L. Esber, Klaus Jansen, Julie Dorsey-Spitz, Merlin L. Robb, Hendrik Streeck, Trevor A. Crowell
Publikováno v:
Vaccine: X, Vol 14, Iss , Pp 100302- (2023)
Future efficacy testing of interventions to prevent HIV or other infections will require engagement of vulnerable populations. We characterized willingness to participate in a future HIV vaccine trial and barriers to participation among men who have
Externí odkaz:
https://doaj.org/article/175347b45c0a412bb6afa805f6f4467a
Autor:
Lay-Myint Yoshida, Kim Mulholland, Stefan Flasche, Cattram Nguyen, Hien-Anh Nguyen, Duc-Anh Dang, Michiko Toizumi
Publikováno v:
Gates Open Research, Vol 7 (2023)
Introduction: The WHO currently recommends giving pneumococcal conjugate vaccines (PCVs) as three doses – either three doses in infancy with Pentavalent vaccine (3p+0), or two doses in infancy followed by a booster around 12 months (2p+1). However,
Externí odkaz:
https://doaj.org/article/30b90f3aec9a417781601ce9ca0ebf91
Akademický článek
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Autor:
Tonia M. Thomas, Susanne H. Hodgson, Katherine Emary, Maia Patrick-Smith, Rebecca te Water Naude, Arabella S. V. Stuart, John Henry, Marcus English, Maria Moore, Naomi Douglas, Andrew J. Pollard, Samantha Vanderslott
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 1 (2023)
In early 2020, adult volunteers were invited to participate in a first-in-human trial of the COVID-19 vaccine, ChAdOx1 nCoV-19, in the United Kingdom (UK) at the height of the global pandemic when there was uncertainty regarding vaccine efficacy and
Externí odkaz:
https://doaj.org/article/70b051222d1f40fb88bb575ee9083151
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 11, Pp 3907-3912 (2021)
This research aims to understand the level and determinants of people’s willingness to participate in a vaccine trial for COVID-19 in Senegal. We conducted a telephone survey among a marginal quota sample of 607 people over 18 years of age. Only 44
Externí odkaz:
https://doaj.org/article/a196df0dc04a4cec81d50aafb7351388
Publikováno v:
Vaccine: X, Vol 12, Iss , Pp 100238- (2022)
According to the World Health Organization, the American region has the highest coronavirus disease-2019 (COVID-19) cases and deaths since the start of the pandemic. This humanitarian tragedy presented the possibility of generating efficacy data from
Externí odkaz:
https://doaj.org/article/5432060a355f4924bdaacab16e99c3aa
Autor:
Tarun Saluja, Bishnu Rath Giri, Shipra Chaudhary, Dipesh Tamrakar, Piush Kanodia, Sonali Palkar, Sridhar Vemula, Suchada Chinaworapong, Bomi Kim, Birendra Prasad Gupta, Sue Kyoung Jo, Sanet Aspinall, Ganesh Kumar Rai, Duncan Steele, Jerome H. Kim, T. Anh Wartel, Sushant Sahastrabuddhe
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 7, Pp 2149-2157 (2021)
Clinical trials are complicated, time-consuming and costly. From the initial screening, informed consent and recruitment of the participants’ to study completion, the sponsor must undertake a wide array of complex and closely monitored operations,
Externí odkaz:
https://doaj.org/article/e12334ef5c8b46b391245a371de2d894
Autor:
Robert L. Murphy, Eustache Paramithiotis, Scott Sugden, Todd Chermak, Bruce Lambert, Damien Montamat-Sicotte, John Mattison, Steve Steinhubl
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
First-generation anit-SARS-CoV-2 vaccines were highly successful. They rapidly met an unforeseen emergency need, saved millions of lives, and simultaneously eased the burden on healthcare systems worldwide. The first-generation vaccines, however, foc
Externí odkaz:
https://doaj.org/article/134f6bfbc1ec429c92ca0123e403b85b