Zobrazeno 1 - 10
of 25 489
pro vyhledávání: '"untranslated region"'
Autor:
Daniel P. Neumann, Katherine A. Pillman, B. Kate Dredge, Andrew G. Bert, Caroline A. Phillips, Rachael Lumb, Yesha Ramani, Cameron P. Bracken, Brett G. Hollier, Luke A. Selth, Traude H. Beilharz, Gregory J. Goodall, Philip A. Gregory
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 199-209 (2024)
Epithelial-mesenchymal transition (EMT) plays important roles in tumour progression and is orchestrated by dynamic changes in gene expression. While it is well established that post-transcriptional regulation plays a significant role in EMT, the exte
Externí odkaz:
https://doaj.org/article/f948ce2e7da94619a7c424e6a9a539bd
Autor:
Eric M. Cockman, Vivek Narayan, Belinda Willard, Sumangala P. Shetty, Paul R. Copeland, Donna M. Driscoll
Publikováno v:
RNA Biology, Vol 16, Iss 12, Pp 1682-1696 (2024)
Selenoproteins are a unique class of proteins that contain the 21st amino acid, selenocysteine (Sec). Addition of Sec into a protein is achieved by recoding of the UGA stop codon. All 25 mammalian selenoprotein mRNAs possess a 3′ UTR stem-loop stru
Externí odkaz:
https://doaj.org/article/13e62b08d7d8470e88c3a2f0917b072a
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1290-1307 (2024)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the coronavirus disease 2019 (COVID-19) pandemic and is continuously spreading globally. The continuous emergence of new SARS-CoV-2 variants keeps posing threats, highlighting th
Externí odkaz:
https://doaj.org/article/aafbf23d340e4dbc9bef5945bcf12f9c
Publikováno v:
Genomics & Informatics, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract The untranslated regions (UTRs) of genes significantly impact various biological processes, including transcription, posttranscriptional control, mRNA stability, localization, and translation efficiency. In functional areas of genomes, non-B
Externí odkaz:
https://doaj.org/article/0b829b77e77242d2bba5aa018fd1c237
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background The 5’ untranslated region of mRNA strongly impacts the rate of translation initiation. A recent convolutional neural network (CNN) model accurately quantifies the relationship between massively parallel synthetic 5’ untransla
Externí odkaz:
https://doaj.org/article/2a26e7d054e444fc8b10d4d212e31d5b
Autor:
Lirong Lin, Yanjing Liu, Rui Liang, Yue Guo, Ruixue Xu, Ruoxi Fan, Zhiwei Jiao, Wenting Zhao, Lixia Yue, Mingke Lu, Shengfa Liu, Xin-zhuan Su, Jian Li
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Background Eukaryotic genes contain introns that are removed by the spliceosomal machinery during mRNA maturation. Introns impose a huge energetic burden on a cell; therefore, they must play an essential role in maintaining genome stability
Externí odkaz:
https://doaj.org/article/303c9e0d8b2b478a845310b46bce9190
Akademický článek
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Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101720- (2024)
We performed single-cell RNA sequencing (scRNA-seq) on a population of 5,000 Tetrahymena thermophila, using the 10x Genomics 3′ gene expression analysis, to investigate gene expression variability within this clonal population. Initially, we estima
Externí odkaz:
https://doaj.org/article/a685a53722974b4681fe1811a2ad89cc
Autor:
Kyung-Ha Lee
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 321-328 (2023)
ABSTRACTThe internal ribosome entry site (IRES) is a unique structure found in the 5’ untranslated region (5'-UTR) of specific messenger RNAs (mRNAs) that allows ribosomes to bind and initiate translation without the need for a cap structure. In th
Externí odkaz:
https://doaj.org/article/9c470d4a55104dce8dc77d80856ab394