Zobrazeno 1 - 10
of 216
pro vyhledávání: '"understudied"'
Autor:
De Wit, Astrid, editor, Brisard, Frank, editor, Madden-Lombardi, Carol, editor, Meeuwis, Michael, editor, Patard, Adeline, editor
Externí odkaz:
https://doi.org/10.1093/oso/9780192849311.001.0001
Autor:
Vincent T. Metzger, Daniel C. Cannon, Jeremy J. Yang, Stephen L. Mathias, Cristian G. Bologa, Anna Waller, Stephan C. Schürer, Dušica Vidović, Keith J. Kelleher, Timothy K. Sheils, Lars Juhl Jensen, Christophe G. Lambert, Tudor I. Oprea, Jeremy S. Edwards
Publikováno v:
PeerJ, Vol 12, p e17470 (2024)
TIN-X (Target Importance and Novelty eXplorer) is an interactive visualization tool for illuminating associations between diseases and potential drug targets and is publicly available at newdrugtargets.org. TIN-X uses natural language processing to i
Externí odkaz:
https://doaj.org/article/960d5f8e591045c1b0baec822e03ab67
Publikováno v:
F1000Research, Vol 13 (2024)
Mosquitoes belonging to the genus Anopheles are the only vectors of human malaria. Anopheles gibbinsi has been linked to malaria transmission in Kenya, with recent collections in Zambia reporting the mosquito species exhibiting zoophilic and exophili
Externí odkaz:
https://doaj.org/article/65df73c9cccc48bd8fd977576a578936
Autor:
Raymond G. Flax, Peter Rosston, Cecilia Rocha, Brian Anderson, Jacob L. Capener, Thomas M. Durcan, David H. Drewry, Panagiotis Prinos, Alison D. Axtman
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Cilia are cellular signaling hubs. Given that human kinases are central regulators of signaling, it is not surprising that kinases are key players in cilia biology. In fact, many kinases modulate ciliogenesis, which is the generation of cilia, and di
Externí odkaz:
https://doaj.org/article/075eef47e68a4433b9e2079571529b77
Autor:
Emmanuel Chabata
Publikováno v:
Studies in African Linguistics, Vol 52, Iss Supplement 13 (2023)
Linguistic corpora are one of the primary research tools in modern-day linguistics. The centrality of corpora derives from the philosophy that data from them is more accurate, observable, objective, reliable and verifiable. However, very little has b
Externí odkaz:
https://doaj.org/article/5eb8b834f3cf4baca32bb01d1ef270df
Publikováno v:
Journal of Zoological and Botanical Gardens, Vol 3, Iss 3, Pp 398-408 (2022)
Exploring the interaction between humans and animals has become increasingly important in the evaluation of well-being for species housed in zoos and aquaria. The COVID-19 pandemic saw the global closure of zoos and aquaria to visitors. Chester Zoo,
Externí odkaz:
https://doaj.org/article/77f1930be17142be8591c42722ce66e0
Autor:
Maria P. Magariños, Anna Gaulton, Eloy Félix, Tevfik Kiziloren, Ricardo Arcila, Tudor I. Oprea, Andrew R. Leach
Publikováno v:
PeerJ, Vol 11, p e15153 (2023)
The patent literature is a potentially valuable source of bioactivity data. In this article we describe a process to prioritise 3.7 million life science relevant patents obtained from the SureChEMBL database (https://www.surechembl.org/), according t
Externí odkaz:
https://doaj.org/article/5dbd917e301f45c7a2da3d708bdd1b1a
Autor:
Travis C. Collier, Yoosook Lee, Mary E. Gebhardt, Douglas E. Norris, Monicah M. Mburu, Limonty Simubali, Sangwoo Seok, Xiaodi Wang, Valerie T. Nguyen
Publikováno v:
F1000Research, Vol 12 (2023)
Despite efforts to minimize the impacts of malaria and reduce the number of primary vectors, malaria has yet to be eliminated in Zambia. Understudied vector species may perpetuate malaria transmission in pre-elimination settings. Anopheles squamosus
Externí odkaz:
https://doaj.org/article/cd40cdbfca774ab1ba5ad53db19746e9
Autor:
Liang-Chin Huang, Rahil Taujale, Nathan Gravel, Aarya Venkat, Wayland Yeung, Dominic P. Byrne, Patrick A. Eyers, Natarajan Kannan
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-25 (2021)
Abstract Background Protein kinases are among the largest druggable family of signaling proteins, involved in various human diseases, including cancers and neurodegenerative disorders. Despite their clinical relevance, nearly 30% of the 545 human pro
Externí odkaz:
https://doaj.org/article/b48b08ad84734cd7aab992cc3ed2eb27
Autor:
Zeina N. Al-Mahayri
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/e3c3dcabb094438db8a9d696dcb3e6fc