Zobrazeno 1 - 10 of 228 pro vyhledávání: '"udc:615"'
1
Population pharmacokinetics of cisplatin in small cell lung cancer patients guided with informative priors
Autor: Jurij Aguiar Zdovc, Mihaela Vaupotič, Gregor Marolt, Lea Knez, Renata Režonja Kukec, Tanja Čufer, Tomaž Vovk, Iztok Grabnar
Publikováno v: Cancer chemotherapy and pharmacology, str. 301-313 : Ilustr., Vol. 90, iss. 4, 2022
COBISS-ID: 25191424
Purpose: Cisplatin-etoposide treatment is recommended as a first line in small cell lung cancer patients (SCLC). However, the prognosis is poor and the dosing is not tailored beyond the body surface area, which is related with indeterminate cisplatin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4af9f8ebc889d7f4a74e1c9263d5dc0
https://doi.org/10.1007/s00280-022-04465-9
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2
The pharmacist's role in the safe and effective use of herbal products
Autor: Bukić, Josipa
Cilj istraživanja: Rastući trend tržišta biljnih proizvoda nije popraćen porastom njihove sigurnosti i učinkovitosti u pacijenata. Biljni lijekovi mogu uzrokovati nuspojave kao i konvencionalna terapija te je nužno da se prijavljuju sve sumnje
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::04556c63947a66038a494937571bcbca
https://urn.nsk.hr/urn:nbn:hr:171:071475
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3
Utjecaj usluge upravljanja farmakoterapijom na kliničke ishode u pacijenata s kardiovaskularnim bolestima na razini primarne zdravstvene zaštite
Autor: Brajković, Andrea
Patients with established cardiovascular diseases (CVDs) often use multiple medications that increase the risk of irrational drug use, subsequently leading to unfavourable clinical and health outcomes. New pharmacist's intervention named Comprehensiv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::afefa2d2bc067283ab99cdfd290912e0
https://repozitorij.pharma.unizg.hr/islandora/object/pharma:2756
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4
High-throughput N-glycosylation analysis of complement component C3 as biomarker of type 1 diabetes
Autor: Šoić, Dinko
Ubrzani razvoj analitičkih tehnika u posljednjih nekoliko desetljeća omogućio je temeljito istraživanje procesa N-glikozilacije u brojnim patofioziološkim stanjima, a uočene promjene u mnogima od njih dovele su do strelovitog rasta interesa za
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c732dd941081a913fda4a983b9be6899
https://repozitorij.pharma.unizg.hr/islandora/object/pharma:2745/datastream/PDF
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5
Aldo-keto reductases and cancer drug resistance
Autor: Tea Lanišnik Rižner, Sravan Jonnalagadda, Trevor M. Penning, Paul C. Trippier
Publikováno v: Pharmacological reviews, vol. 73, no. 3, pp. 1150-1171, 2021.
Pharmacol Rev
Human aldo-keto reductases (AKRs) catalyze the NADPH-dependent reduction of carbonyl groups to alcohols for conjugation reactions to proceed. They are implicated in resistance to cancer chemotherapeutic agents either because they are directly involve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452ea540f0bdd39057a4ef2a678839ff
https://repozitorij.uni-lj.si/IzpisGradiva.php?id=144716
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6
Quantification of serum M-protein by immunosubstraction method
Autor: Šegulja, Dragana
Prisutnost M-proteina u serumu karakterizira stanje monoklonske gamapatije. Koncentracija M-proteina izravno korelira s veličinom tumorske mase, osim u vrlo rijetkim slučajevima nesekrecijske bolesti. Detekcija, tipizacija i kvantifikacija M-protei
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3671::fa8a393d1b8c8ec95c4c1748aee2fb79
https://repozitorij.pharma.unizg.hr/islandora/object/pharma:2730
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7
Discovery and hit-to-lead optimization of benzothiazole scaffold-based DNA gyrase inhibitors with potent activity against Acinetobacter baumannii and Pseudomonas aeruginosa
Autor: Andrej Emanuel Cotman, Martina Durcik, Davide Benedetto Tiz, Federica Fulgheri, Daniela Secci, Maša Sterle, Štefan Možina, Žiga Skok, Nace Zidar, Anamarija Zega, Janez Ilaš, Lucija Peterlin Mašič, Tihomir Tomašič, Diarmaid Hughes, Douglas L. Huseby, Sha Cao, Linnéa Garoff, Talía Berruga Fernández, Paraskevi Giachou, Lisa Crone, Ivailo Simoff, Richard Svensson, Bryndis Birnir, Sergiy V. Korol, Zhe Jin, Francisca Vicente, Maria C. Ramos, Mercedes de la Cruz, Björn Glinghammar, Lena Lenhammar, Sara R. Henderson, Julia E. A. Mundy, Anthony Maxwell, Clare E. M. Stevenson, David M. Lawson, Guido V. Janssen, Geert Jan Sterk, Danijel Kikelj
Publikováno v: Journal of medicinal chemistry, vol. 66, no. 2, 2023.
Journal of medicinal chemistry, str. 1380-1425 : Ilustr., Vol. 66, no. 2, 2023
COBISS-ID: 512806681
Journal of medicinal chemistry, 66(2), 1380-1425. American Chemical Society
Cotman, A E, Durcik, M, Benedetto Tiz, D, Fulgheri, F, Secci, D, Sterle, M, Možina, Š, Skok, Ž, Zidar, N, Zega, A, Ilaš, J, Peterlin Mašič, L, Tomašič, T, Hughes, D, Huseby, D L, Cao, S, Garoff, L, Berruga Fernández, T, Giachou, P, Crone, L, Simoff, I, Svensson, R, Birnir, B, Korol, S V, Jin, Z, Vicente, F, Ramos, M C, De La Cruz, M, Glinghammar, B, Lenhammar, L, Henderson, S R, Mundy, J E A, Maxwell, A, Stevenson, C E M, Lawson, D M, Janssen, G V, Sterk, G J & Kikelj, D 2023, ' Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa ', Journal of medicinal chemistry, vol. 66, no. 2, pp. 1380-1425 . https://doi.org/10.1021/acs.jmedchem.2c01597
We have developed compounds with a promising activity against Acinetobacter baumannii and Pseudomonas aeruginosa, which are both on the WHO priority list of antibiotic-resistant bacteria. Starting from DNA gyrase inhibitor 1, we identified compound 2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20d28e0e61c3b400f08f6903958d25f
https://repozitorij.uni-lj.si/Dokument.php?id=166579&dn=
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8
Pharmacist-led clinical medication review service in primary care
Autor: Nabergoj Makovec, Urška, Tomšič, Tanja, farmacevtka, Kos, Mitja, Stegne Ignjatović, Tea, PoplasSusič, Tonka
Publikováno v: BMC primary care, vol. 24, no. 6, 2023.
BMC primary care, 13 str. : ilustr., Vol. 24, art. 6, 2023
COBISS-ID: 114320643
Background: An advanced level medication review service (CMR) is systematically reimbursed and available nationwide in Slovenian primary care since 2016. CMR is performed by clinical pharmacists (CP). Close collaboration with general practitioner (GP
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b311577badae989873d9a353b149e106
https://hdl.handle.net/20.500.12556/RUL-143745
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9
Modeliranje fotokatalitičke razgradnje farmaceutika u vodi višestranim pristupom
Autor: Tomić, Antonija
Pharmaceuticals, as one of the largest groups of contaminants of emerging concern (CECs), pose a threat to the environment and human health. Advanced Oxidation Processes (AOPs) have proven to be effective in the degradation of persistent, toxic, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::862f28f0fd01b3ca6133428b2a29e799
https://repozitorij.fkit.unizg.hr/islandora/object/fkit:1578
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10
New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus
Autor: Martina Durcik, Andrej Emanuel Cotman, Žan Toplak, Štefan Možina, Žiga Skok, Petra Eva Szili, Márton Czikkely, Elvin Maharramov, Thu Hien Vu, Maria Vittoria Piras, Nace Zidar, Janez Ilaš, Anamarija Zega, Jurij Trontelj, Luis A. Pardo, Diarmaid Hughes, Douglas Huseby, Tália Berruga-Fernández, Sha Cao, Ivailo Simoff, Richard Svensson, Sergiy V. Korol, Zhe Jin, Francisca Vicente, Maria C. Ramos, Julia E. A. Mundy, Anthony Maxwell, Clare E. M. Stevenson, David M. Lawson, Björn Glinghammar, Eva Sjöström, Martin Bohlin, Joanna Oreskär, Sofie Alvér, Guido V. Janssen, Geert Jan Sterk, Danijel Kikelj, Csaba Pal, Tihomir Tomašič, Lucija Peterlin Mašič
Publikováno v: Durcik, M, Cotman, A E, Toplak, Ž, Možina, Š, Skok, Ž, Szili, P E, Czikkely, M, Maharramov, E, Vu, T H, Piras, M V, Zidar, N, Ilaš, J, Zega, A, Trontelj, J, Pardo, L A, Hughes, D, Huseby, D, Berruga-Fernández, T, Cao, S, Simoff, I, Svensson, R, Korol, S V, Jin, Z, Vicente, F, Ramos, M C, Mundy, J E A, Maxwell, A, Stevenson, C E M, Lawson, D M, Glinghammar, B, Sjöström, E, Bohlin, M, Oreskär, J, Alvér, S, Janssen, G V, Sterk, G J, Kikelj, D, Pal, C, Tomašič, T & Peterlin Mašič, L 2023, ' New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus ', Journal of medicinal chemistry, vol. 66, no. 6, pp. 3968-3994 . https://doi.org/10.1021/acs.jmedchem.2c01905
Journal of medicinal chemistry, 66(6), 3968-3994. American Chemical Society
Journal of Medicinal Chemistry
Journal of medicinal chemistry, str. 3968-3994 : Ilustr., Vol. 66, iss. 6, 2023
COBISS-ID: 512806681
Journal of medicinal chemistry, vol. 66, no. 6, pp. 3968-3994, 2023.
A new series of dual low nanomolar benzothiazole inhibitors of bacterial DNA gyrase and topoisomerase IV were developed. The resulting compounds show excellent broad-spectrum antibacterial activities against Gram-positive Enterococcus faecalis, Enter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c3d01f7594899ad1504d0f95893f77
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-501871
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