Zobrazeno 1 - 10
of 4 024
pro vyhledávání: '"ubiquitin-conjugating enzyme"'
LncRNA AFAP1-AS1 Promotes Oral Squamous Cell Carcinoma Development by Ubiquitin-Mediated Proteolysis
Publikováno v:
International Dental Journal, Vol 74, Iss 6, Pp 1277-1286 (2024)
Background and purpose: Long noncoding RNA (lncRNA) dysregulation has been reported to play a pivotal role in the development of cancers. In this study, we aimed to screen the key lncRNA in oral squamous cell carcinoma (OSCC) via bioinformatics analy
Externí odkaz:
https://doaj.org/article/463e13ff71f84c0cbd20dd0a9295ae3d
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract The ubiquitination is crucial for controlling cellular homeostasis and protein modification, in which ubiquitin-conjugating enzyme (E2) acts as the central player in the ubiquitination system. Ubiquitin-conjugating enzymes, which have specia
Externí odkaz:
https://doaj.org/article/2bbe628fc7514146a96e1883b93532d4
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-18 (2023)
Abstract Background Epithelial ovarian cancer (OC) is the fourth leading cause of cancer-related deaths in women, with a 5-year survival rate of 30%-50%. Platinum resistance is the chief culprit for the high recurrence and mortality rates. Several st
Externí odkaz:
https://doaj.org/article/d4aebbef01e34c48bda74135becf498d
Autor:
Samuel O. Lord, Peter W.J. Dawson, Jitpisute Chunthorng-Orn, Jimi Ng, Leslie M. Baehr, David C. Hughes, Pooja Sridhar, Timothy Knowles, Sue C. Bodine, Yu-Chiang Lai
Publikováno v:
Biochemistry and Biophysics Reports, Vol 37, Iss , Pp 101636- (2024)
MuRF1 (Muscle-specific RING finger protein 1; gene name TRIM63) is a ubiquitin E3 ligase, associated with the progression of muscle atrophy. As a RING (Really Interesting New Gene) type E3 ligase, its unique activity of ubiquitylation is driven by a
Externí odkaz:
https://doaj.org/article/57a348147d7a4823b20995284b48205a
Publikováno v:
Phytopathology Research, Vol 5, Iss 1, Pp 1-12 (2023)
Abstract Anthracnose is a common disease found in Camellia oleifera producing areas across China, whose primary pathogen is Colletotrichum fructicola. We previously revealed that autophagy is essential for the pathogenicity of C. fructicola. However,
Externí odkaz:
https://doaj.org/article/317299dcfdc44212a22a1c320aab6f39
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2024)
Protein ubiquitination plays a pivotal role in protein homeostasis. Ubiquitination may regulate the stability, activity, protein–protein interaction, and localization of a protein. Ubiquitination is subject to regulation by two groups of counteract
Externí odkaz:
https://doaj.org/article/b4e5b2cf61444842a46a07ae0e54e6f5
Autor:
Lin-Lin Xu, Ting Gan, Yang Li, Pei Chen, Su-Fang Shi, Li-Jun Liu, Ji-Cheng Lv, Hong Zhang, Xu-Jie Zhou
Publikováno v:
Kidney Diseases, Pp 1-1 (2024)
Introduction: IgA nephropathy (IgAN) is a leading cause of end-stage renal disease. The exact pathogenesis of IgAN is not well defined, but some genetic studies have led to a novel discovery that the (immuno)proteasome probably plays an important rol
Externí odkaz:
https://doaj.org/article/62eaa1af4a7a426aa07fd5836c7c139c
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Autor:
Yunfei Han, Chuanzhong Zhang, Hanjing Sha, Xiaojing Wang, Yue Yu, Jia Liu, Guangxin Zhao, Jingying Wang, Guankai Qiu, Xingjian Xu, Jun Fang
Publikováno v:
Rice, Vol 16, Iss 1, Pp 1-15 (2023)
Abstract Rice has 48 ubiquitin-conjugating enzymes, and the functions of most of these enzymes have not been elucidated. In the present study, a T-DNA insertional mutant named R164, which exhibited a significant decrease in the length of primary and
Externí odkaz:
https://doaj.org/article/6a08f3f2c5fa4d5984cae00f3bbd4f44